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Overview of Visfatin Levels in Pregnant Women as a Stunting Biomarker Ni Nyoman Astika Dewi; Luh Putu Rinawati; Ni Putu Ditya Prabandari Dewi; I Made Krishna Paramartha; Ni Putu Intan Maha Ayu Diyanti; Aprilia Rakhmawati; Heri Setiyo Bekti
JURNAL KEBIDANAN Vol 12, No 1 (2022): April 2022
Publisher : Politeknik Kesehatan Kementerian Kesehatan Semarang

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.31983/jkb.v12i1.8018

Stunting is one of the malnutrition problems experienced by toddlers in the world. Indonesia is the third country in the prevalence of stunting in the Southeast Asian region. Visfatin is one of the molecules that play a role in fetal development during the womb. Reports related to visfatin in pregnant women are still very few, and mention visfatin plays a role in the incidence of preeclampsia (PE), fetal growth restriction, and gestational diabetes mellitus (GDM). This study aims to determine the level of visfatin in pregnant women as a biomarker of stunting in Bangli Regency, Bali Province. This research is a descriptive study, with an observational design. Blood samples were taken from the median cubital vein. Samples were examined by ELISA method. In the examination of vistafin levels in 30 pregnant women, the lowest level being 0.53 ng/ml and the highest level being 56.72 ng/ml. From the results obtained and compared with previous studies, the visfatin levels obtained were lower than the visfatin levels in normal pregnant women. Many studies have shown that increased levels of visfatin in maternal plasma are associated with low birth weight and intrauterine growth restriction (IUGR). Babies born with LBW have a risk of stunting.

Gambaran Kadar Glukosa dan Total Kolesterol pada Wanita Hamil di Kabupaten Bangli, Bali: An Overview of Glucose Levels and Total Cholesterol Levels among Pregnant Women in Bangli District, Bali Heri Setiyo Bekti; Ni Nyoman Astika Dewi; Luh Putu Rinawati; Luh Ade Wilankrisna; I Made Suarjana; I Made Yogi Hardiyanta; Ni Putu Lisa Anjani; Aprilia Rakhmawati
Jurnal Bidan Cerdas Vol. 4 No. 2 (2022)
Publisher : Poltekkes Kemenkes Palu

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.33860/jbc.v4i2.1024

Introduction: Gestational diabetes mellitus (GDM) is a state of glucose intolerance that was first detected during pregnancy. GDM is increasing worldwide, it is estimated that 15% to 22% of all pregnancies are affected by GDM. GDM can be associated with many consequences, such as fetal macrosomia, preeclampsia, and high caesarean rates. The purpose of this study was to determine the description of glucose and total cholesterol levels in pregnant women in Bangli Regency, Bali. Methods: This research method is descriptive by checking glucose and total cholesterol levels using the enzymatic-colorimetric method. The subjects in this study were 33 pregnant women, with sampling method using the probability sampling method, with a simple random sampling technique. Results: The result of this study is, glucose levels in all samples were in the normal category, while for total cholesterol levels 48,48% were in the normal category and 42,42% were in the abnormal category. Conclusion: Normal glucose levels can be caused by several factors such as the age of the respondent under 40 years, gestational age at term, and the hormones that regulate blood glucose in the body functioning properly. An increase in cholesterol levels can be caused by an increase in sexsteroid hormones, as well as changes in liver and adipose tissue metabolism. An increase in total cholesterol levels in pregnant women needs to be watched out for because it can be on of the markers of the incidence of GDM. ABSTRAK Pendahuluan: Diabetes melitus gestasional (DMG) merupakan keadaan intoleransi glukosa yang pertama kali terdeteksi selama kehamilan. DMG meningkat di seluruh dunia, diperkirakan 15% sampai 22% dari semua kehamilan dipengaruhi oleh DMG. DMG dapat dikaitkan dengan banyak konsekuensi, seperti makrosomia janin, preeklampsia, dan tingkat operasi caesar yang tinggi. Tujuan dari penelitian ini adalah untuk mengetahui gambaran kadar glukosa sewaktu dan kolesterol total pada ibu hamil di Kabupaten Bangli, Bali. Metode: Metode penelitian ini adalah deskriptif dengan memeriksa kadar glukosa sewaktu dan kolesterol total menggunakan metode enzimatik kolorimetri. Subyek pada penelitain 33 ibu hamil, dengan cara penarikan sampel dengan mengunakan metode probality sampling, dengan teknik simple random sampling. Hasil: Hasil dari penelitian ini, diperoleh kadar glukosa sewaktu seluruh sampel berada pada kategori normal sedangkan untuk kadar kolesterol total sebanyak 48,48% berada pada kategori normal dan 42,42% pada kategori abnormal. Kesimpulan: Kadar glukosa yang normal dapat disebabkan oleh usia repsonden di bawah 40 tahun, usia kehamilan yang cukup bulan, dan hormon pengatur glukosa yang berfungsi dengan baik. Peningkatan kadar kolesterol total dapat disebabkan oleh peningkatan hormon steroid seks, perubahan metabolisme hati dan jaringan adipose. Peningkatan kadar kolesterol total pada ibu hamil perlu diwaspadai karena dapat menjadi salah satu penanda kejadian DMG.

GAMBARAN KADAR GLUKOSA DARAH SEWAKTU PADA WANITA MENOPAUSE DI KELURAHAN BITERA KECAMATAN GIANYAR Kadek Aprilya; I Nyoman Gede Suyasa; Ni Nyoman Astika Dewi
Jurnal Skala Husada : The Journal of Health Vol 19, No 2 (2022): Jurnal Skala Husada: The Journal of Health
Publisher : Poltekkes Kemenkes Denpasar

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.33992/jsh:tjoh.v19i2.2309

energy which is absorbed in large quantities into the blood and converted in the liver. Increased body fat in menopausal women has an important role in the development of insulin resistance after menopause which can increase blood glucose levels. Purpose The purpose of this study was to determine the description of blood glucose levels in menopausal women in Bitera Village, Gianyar District. Method used in is a descriptive research conducted in January – May 2022 with a total of 60 respondents obtained by random sampling technique. Blood glucose levels were measured by the Point Of Care Testing (POCT) method. Result showed that menopausal women with blood glucose levels (1.67%) in the low category, (56.67%) in the normal category, and (41.67%) in the high category. Age group Blood Glucose levels When high the age group 50-54 years as much as (36.00%). Blood Glucose Levels When high were more commonly found in the fat BMI category (72.00%). Based on physical activity, menopausal women who sometimes have blood glucose levels while doing sports (80.00%). Menopausal women who do not have a hereditary history of diabetes are more dominant in having blood glucose levels over time as much as (52.00%). Conclusion The categories of respondents who have high blood glucose levels of age group 50-54 years, fat BMI, moderate physical activity, and no hereditary history of diabetes.

FAKTOR INDIVIDU, FAKTOR LINGKUNGAN DAN KEKURANGAN ENERGI KRONIS (KEK) PADA IBU HAMIL DI PUSKESMAS MENGWI I Ni Wayan Eka Krisna Putri; A.A. Ngurah Kusumajaya; Ni Nyoman Astika Dewi
Jurnal Ilmu Gizi : Journal of Nutrition Science Vol 8, No 4 (2019): November 2019
Publisher : Poltekkes Kemenkes Denpasar dan DPD PERSAGI Bali

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.33992/jig.v8i4.767

The nutritional status of pregnant women is one indicator in measuring the nutritional status of the community. If the input of nutrition for pregnant women from food is not balanced with the needs of the body there will be a deficiency of nutrients. Chronic energy deficiency can occur in women of childbearing age and in pregnant women. A person is said to suffer the risk of Chronic Energy Deficiency when the Upper Arm Circumference is 23.5 cm. The purpose of this study was to determine the relationship between individual factors and environmental factors that affect the lack of chronic energy (kek) in the Mengwi I Public Health Center. This type of research was observational with a cross-sectional design. The sample obtained was 57 pregnant women. Statistical tests using chi-square. Age of risky pregnant women is 7 people (12.3%). Low maternal education is 14 people (24.6%). The work of pregnant women who work is 37 people (64.9%). The family income of pregnant women UMR is 28 people (49.1%). There were 10 pregnant women (17.5%). Parity pregnant with a multipara category of 20 people (35.1%). Pregnant women with less attitudes as many as 26 people (45.6%). Pregnant women who behave less as many as 38 people (66.7%). Pregnant women with less family support are 29 people (50.9%). On all individual factor variables and environmental factors that affect the health of pregnant women p value α (p 0.05), which means there is no relationship between maternal age and mortality, education with income, employment with income, income with income, parity with kek, attitude with kek, and family support with kek.Keywords: Individual, Enviromental Factors, Chronic energy deficiency

MEMBANTU PENANGANAN MASALAH KESEHATAN MASYARAKAT DENGAN INTERPROFESIONAL EDUCATION (IPE) Mochammad Choirul Hadi; Anak Agung Ngurah Kusumajaya; Gusti Ayu Marhaeni; I Wayan Mustika; I Nyoman Gejir; Ketut Sudiantara; I Wayan Suardana; I Gusti Putu Sudita Puryana; Ni Nyoman Astika Dewi; Nur Habibah
Jurnal Pengabmas Masyarakat Sehat Vol 5, No 1 (2023)
Publisher : Poltekkes Kemenkes Denpasar

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.33992/jpms.v5i1.2115

An integrated manner of Community Engagement Activities done by using the concept of Interprofessional Education (IPE) engages health workers and village midwives in the work area of Puskesmas Kerambitan I as the target. This activity aims to apply the IPE to improve community health status in the working area of Puskesmas Kerambitan I Tabanan Regency. In the implementation of community service activities used several methods, such as structured interview methods to explore public health problems, methods of extension for giving some health materials as well as, and methods of direct practice to the community during the day of health services. This activity successfully involves the target of training of 30 people consisting of Village Midwife and Community Health Center Staff and Health Workers from 7 villages as many as 21 people, and target of public health service as much as 98 out of 100 people invited Community Service Activity with IPE method is completed by involving all departments in Poltekkes Kemenkes Denpasar.

MEMBANTU PENANGANAN MASALAH KESEHATAN MASYARAKAT DENGAN INTERPROFESIONAL EDUCATION (IPE) Mochammad Choirul Hadi; Anak Agung Ngurah Kusumajaya; Gusti Ayu Marhaeni; I Wayan Mustika; I Nyoman Gejir; Ketut Sudiantara; I Wayan Suardana; I Gusti Putu Sudita Puryana; Ni Nyoman Astika Dewi; Nur Habibah
Jurnal Pengabmas Masyarakat Sehat Vol 5, No 1 (2023)
Publisher : Poltekkes Kemenkes Denpasar

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.33992/jpms.v5i1.2115

An integrated manner of Community Engagement Activities done by using the concept of Interprofessional Education (IPE) engages health workers and village midwives in the work area of Puskesmas Kerambitan I as the target. This activity aims to apply the IPE to improve community health status in the working area of Puskesmas Kerambitan I Tabanan Regency. In the implementation of community service activities used several methods, such as structured interview methods to explore public health problems, methods of extension for giving some health materials as well as, and methods of direct practice to the community during the day of health services. This activity successfully involves the target of training of 30 people consisting of Village Midwife and Community Health Center Staff and Health Workers from 7 villages as many as 21 people, and target of public health service as much as 98 out of 100 people invited Community Service Activity with IPE method is completed by involving all departments in Poltekkes Kemenkes Denpasar.

Gambaran Kadar Hemoglobin pada Remaja Putri (Studi Kasus di SMA Negeri 2 Denpasar) Kadek Indra Trisna Dewi; Heri Setiyo Bekti; Luh Ade Wilan Krisna; Ni Nyoman Astika Dewi
Jurnal Skala Husada : The Journal of Health Vol 20, No 2 (2023): JSH: Jurnal Skala Husada-The Journal of Health
Publisher : Poltekkes Kemenkes Denpasar

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.33992/jsh:tjoh.v20i2.2758

Prevalensi anemia pada remaja putri di dunia dilaporkan berkisar 40-88%. Remaja putri dengan anemia dapat mempengaruhi penurunan produktivitas kerja atau kemampuan akademik di sekolah karena kurangnya semangat belajar dan fokus. Anemia pada remaja putri dapat berlanjut selama kehidupan remaja putri tersebut dan berisiko menjadi ibu hamil dengan anemia yang dapat melahirkan bayi prematur dan berujung stunting. Penelitian ini bertujuan untuk mengetahui gambaran kadar hemoglobin pada remaja putri di SMA Negeri 2 Denpasar. Jenis penelitian yang digunakan adalah deskriptif dengan sampel sebanyak 42 orang remaja putri yang dipilih dengan teknik proportionate stratified random sampling. Pemeriksaan kadar hemoglobin dilakukan menggunakan metode Point of Care Testing (POCT) dengan menggunakan darah kapiler. Hasil penelitian menujukan bahwa kadar hemoglobin paling banyak normal yaitu sebanyak 29 responden (69,0%), kadar hemoglobin rendah sebanyak 7 responden (16,7%), dan kadar hemoglobin tinggi sebanyak 6 responden (14,3%). Gambaran kadar hemoglobin pada remaja putri di SMA Negeri 2 Denpasar sebagian besar memiliki kadar hemoglobin normal.

IRRITATION TEST OF LIQUID ANTIBACTERIAL SOAP COMBINING LEGUNDI AND GREEN BETEL LEAVE EXTRACTS ON WHITE RATS (Rattus norvegicus) Ida Bagus Oka Suyasa; Ni Nyoman Astika Dewi; Made Delia Budi Apriliapatni; Surya Natallia Bryan
Meditory : The Journal of Medical Laboratory Vol 13, No 1 (2025): Meditory, Volume 13 No. 1 Tahun 2025
Publisher : Jurusan Teknologi Laboratorium Medis, Poltekkes Kemenkes Denpasar

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.33992/meditory.v13i1.4067

Background: Soap is a cleanser that is made with a chemical reaction. Soap preparations with active ingredients derived from nature are also widely circulated. Natural ingredients that have many active substances are legundi leaves and green betel leaves. Two antimicrobial agents from these ingredients working simultaneously on a homogeneous microbial population will have a synergistic effect.Objective: This study aims to determine the safety of using an antibacterial liquid soap formula with a combination of legundi and betel leaf extracts.Methods: This study is an experimental research that includes physicochemical testing of the soap formula, organoleptic evaluation, and irritation testing on white rats (Rattus norvegicus) using the Draize method with a posttest-only control group design. This research was analyzed descriptively. This study adheres to the ethical principle of beneficence, prioritizing the well-being and safety of all participants.Results: Organoleptic test, pH test, homogeneity test, and water content test meet Indonesian National Standard requirements, and there is no irritation in experimental animals.Conclusions: An antibacterial liquid soap formula with a combination of legundi and betel leaf extracts is safe.

PHYTOCHEMICAL PROFILING AND ANTIOXIDANT PROPERTIES OF ETHANOL EXTRACT OF TAKOKAK EGGPLANT LEAVES (Solanum torvum) Ni Wayan Mita Efianti; Gusti Ayu Made Ratih; Ni Nyoman Astika Dewi
Meditory : The Journal of Medical Laboratory Vol 13, No 1 (2025): Meditory, Volume 13 No. 1 Tahun 2025
Publisher : Jurusan Teknologi Laboratorium Medis, Poltekkes Kemenkes Denpasar

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.33992/meditory.v13i1.3980

Background: Takokak eggplant (Solanum torvum) has been traditionally used in medicine, and its secondary metabolites possess antioxidant potential.Objective: This study aimed to determine the phytochemical profiling and analyze the antioxidant properties of Takokak eggplant leaf extract (Solanum torvum) using ethanol solvent.Methods: An experimental research design was used. Antioxidant activity was tested using the DPPH method.Results: Phytochemical screening test of the 70% ethanol extract revealed the presence of flavonoids, terpenoids, saponins, and tannins, while the 96% ethanol extract of Takokak eggplant leaves (Solanum torvum) contained only flavonoids, terpenoids, and tannins. Antioxidant activity tests showed that the IC50 (Inhibition Concentration) value of 70% ethanol extract was 49.9 ppm (very active), and 96% ethanol extract was 65.7 ppm (active). The AAI (Antioxidant Activity Index) value of the 70% ethanol extract was 0.80, while the 96% ethanol extract was 0.60.Conclusions: Takokak eggplant leaf extract (Solanum torvum) with 70% ethanol had higher phytochemical content and antioxidant activity than 96% ethanol.

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