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All Journal Jurnal Biogenerasi Jurnal Pengabdian Masyarakat Multidisiplin Jurnal Ilmiah Kesehatan Masyarakat BIO-CONS: Jurnal Biologi dan Konservasi Jurnal Mahasiswa Ilmu Kesehatan Jurnal Ilmiah Manuntung: Sains Farmasi dan Kesehatan
Dini Mardhiyani
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Aerospace Engineering Agriculture, Biological Sciences & Forestry Humanities Astronomy Automotive Engineering Biochemistry, Genetics & Molecular Biology Chemistry Civil Engineering, Building, Construction & Architecture Computer Science & IT Control & Systems Engineering Decision Sciences, Operations Research & Management Dentistry Earth & Planetary Sciences Education Electrical & Electronics Engineering Energy Environmental Science Health Professions Immunology & microbiology Languange, Linguistic, Communication & Media Law, Crime, Criminology & Criminal Justice Materials Science & Nanotechnology Mathematics Medicine & Pharmacology Nursing Public Health Social Sciences Veterinary Other

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FORMULASI SEDIAAN OBAT KUMUR KOMBINASI EKSTRAK DAUN GAMBIR (Uncraina gambir (Hunter) Roxb) dan BIJI PINANG (Areca catechu L.) SEBAGAI ANTIBAKTERI Dini Mardhiyani
Jurnal Biogenerasi Vol. 8 No. 1 (2023): Volume 8 Nomor 1 Tahun 2023
Publisher : Universitas Cokroaminoto Palopo

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.30605/biogenerasi.v8i1.2216

Abstract

Bad breath (Halitosis) is one of the oral health problems that many people complain about after caries and periodontal disease. Plants that have the potential to be used as mouthwash preparations are gambier leaves and areca nut seeds. The content of phenol and catechin compounds has the ability as a bactericidal. Meanwhile, areca nut has the ability to inhibit the release of calcium ions in the tooth demineralization process stimulated by Streptococcus mutans. This study aims to determine the evaluation results of a combination of gambier leaf and areca nut mouthwash preparations with concentrations of 0.5%, 1%, and 1.5% with several physical parameters, namely organoleptic tests, pH tests, clarity tests, and viscosity tests. Physical stability testing was carried out on Day 0 and Day 7. The results of the organoleptic test are liquid, odorless, white and yellowish brown, sweet and bitter taste. ptest day 0 on controls, F1, F2, and F3, namely 6.2, 4.8, 4.8, 4.6, and day 7 on controls, F1, F2, and F3, namely 6.2, 4 ,7, 4,6, 4,4. Clarity test on day 0 and day 7 controls, F1, F2, and F3 were clear. Viscosity test day 0 on controls, F1, F2, and F3, namely 11.40 cPoises, 9.88 cPoises, 7,271 cPoises, 10.13 cPoises and day 7 on controls, F1, F2, and F3, namely 7,725 cPoises, 9,380 cPoises, 10,218 cPoises, 11 cPoises.
PEMBERDAYAAN IBU RUMAH TANGGA DI DESA KARYA INDAH MELALUI PEMBUATAN CEMILAN SEHAT NUGGET KURKUMIN Dini Mardhiyani; Eva Oktariani; Denia Pratiwi; Deri Islami
Jurnal Pengabdian Masyarakat Multidisiplin Vol 6 No 2 (2023): Februari
Publisher : LPPM Universitas Abdurrab

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.36341/jpm.v6i2.3106

Abstract

This community service activity was carried out with PKK mothers in Karya Indah Village, Kec. Tapung, Kab. Kampar, Riau. Law Number 6 of 2014 article 6 concerning Villages states that village arrangements aim to advance the economy of village communities and overcome national development gaps. The village community without exception includes women in the village of Karya Indah Village, Kec. Tapung, Riau is actually a village potential and asset that can help improve family welfare in particular and improve village welfare in general. The service method is carried out by providing counseling, demonstrations and training. The purpose of this service is expected to solve community problems, namely the low ability of the community in entrepreneurship so that they can contribute to increasing the potential of partners, especially the community by improving the quality of human resources. The level of achievement of the goals of this service program can be said to be successful, which can be seen from the enthusiasm of the participants in participating in the service activities and the ability of the service participants to answer questions after completing the counseling and training provided. The recommendation from this community service activity is that it is necessary to have similar repetitive activities related to training which are related to increasing the potential of the community through training.
Aktivitas Antioksidan Ekstrak Etanol Daun Bidara (Ziziphus Mauritiana Lam) dengan Metode DPPH Dini Mardhiyani; Melinda Rehulina
BIO-CONS : Jurnal Biologi dan Konservasi Vol. 5 No. 1 (2023): BIO-CONS: Jurnal Biologi dan Konservasi
Publisher : PROGRAM STUDI PENDIDIKAN BIOLOGI

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.31537/biocons.v5i1.1089

Abstract

Daun bidara memiliki banyak kandungan yang bermanfaat,antara lain; mengandung nutrisi protein, kalsium, zat besi, magnesium, vitamin, senyawa aktif seperti flavonoid, karotenoid, alkaloid, fenol, kuersetin, metil ester, terpenoid, saponin dan lain sebagainya. Penelitian ini bertujuan untuk mengetahui aktivitas antioksidan pada ekstrak daun bidara dengan menggunakan metode DPPH (2-difenil-1-pikrilhidrazi). Penelitian ini menggunakan sampel daun bidara (Ziziphus mauritiana Lam) yang direndam dengan pelarut yang sesuai yaitu etanol 70% dan menggunakan pembanding vitamin C. Pengujian aktivitas antioksidan dalam penelitian ini menggunakan metode penangkap radikal bebas DPPH pada panjang gelombang 520 nm. Berdasarkan hasil penelitian menunjukkan bahwa aktivitas antioksidan daun bidara didapatkan nilai Inhibition Concentration (IC50) sampel daun bidara sebesar 263,2107 ?g/ml dan nilai Antioixidant Activity Index (AAI) yaitu 0,30, dan nilai Inhibition Concentration (IC50) vitamin C sebesar 18,8337 ?g/ml. Hasil tersebut menunjukkan bahwa sampel daun bidara mempunyai aktivitas antioksidan yang rendah.
Literature Review: Pengaruh Edukasi Terhadap Pengetahuan dan Kepatuhan Mengonsumsi Obat pada Pasien Diabetes Mellitus Dini Mardhiyani; Juwana janu
Jurnal Mahasiswa Ilmu Kesehatan Vol. 3 No. 2 (2025): Jurnal Mahasiswa Ilmu Kesehatan
Publisher : STIKes Ibnu Sina Ajibarang

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.59841/jumkes.v3i2.2577

Abstract

Diabetes Mellitus (DM) is a chronic disease that requires long-term adherence to treatment. One of the main challenges in managing type 2 DM is the low level of patient adherence to medication. This literature review aims to analyze the effect of health education on improving patients’ knowledge and medication adherence. The review is based on selected scientific articles that discuss the relationship between education, knowledge, and adherence in patients with DM. Findings indicate that health education-delivered through counseling, printed media, self-instructional modules, or home visits—generally improves patients’ understanding of the disease and the importance of regular treatment. This increase in knowledge contributes to better health behavior, particularly in terms of medication compliance. Interactive educational methods that involve healthcare providers and patient families are more effective than one-way communication approaches. Structured and continuous education tailored to patient characteristics has the potential to significantly enhance disease management. Therefore, health education should be prioritized as a key strategy to improve treatment adherence and prevent long-term complications in patients with diabetes mellitus.
Pengaruh Kehadiran Apoteker terhadap Standar Pelayanan Kefarmasian di Apotek Kabupaten Rokan Hulu Diana Resky; Dini Mardhiyani
SEHATMAS: Jurnal Ilmiah Kesehatan Masyarakat Vol. 4 No. 2 (2025): April 2025
Publisher : Yayasan Literasi Sains Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.55123/sehatmas.v4i2.4890

Abstract

The standard of pharmaceutical services serves as a benchmark, especially for pharmacists, in providing pharmaceutical care. This study aims to examine the impact of pharmacists' presence on pharmaceutical services. The research uses a cross-sectional method with a questionnaire as the measurement tool, conducted from April to May 2023. The study sample consists of 31 respondents who are pharmaceutical personnel in pharmacies in Rokan Hulu Regency. The results show that the percentage of pharmacist presence in pharmacies in Rokan Hulu Regency is only 43.46%, which is still considered low. A simple linear regression analysis indicates that the coefficient value of pharmacist presence is 53.310. The linear regression coefficient for Rokan Hulu Regency is 0.404. Based on the coefficient of determination test, the pharmacist presence variable (X) has a high influence on the quality of pharmaceutical services (Y), with a contribution of 79%. The F-test results show a value of 18.769 with a significance level of 0.007 (p<0.05), concluding that the pharmacist presence variable significantly affects pharmaceutical services. Moreover, pharmacist presence contributes to improving key service aspects, such as pharmaceutical supply management, drug information services, and patient counseling. Therefore, efforts to increase pharmacist presence in pharmacies are necessary to ensure pharmaceutical services are more optimal and comply with established standards.
Kontribusi Kegemukan dan Resistensi Insulin dalam Perkembangan Sindrom Ovarium Polikistik: Suatu Kajian Pustaka Janu, Juwana; Dini Mardhiyani
Jurnal Mahasiswa Ilmu Kesehatan Vol. 3 No. 2 (2025): Jurnal Mahasiswa Ilmu Kesehatan
Publisher : STIKes Ibnu Sina Ajibarang

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.59841/jumkes.v3i2.2581

Abstract

Polycystic Ovary Syndrome (PCOS) is a complex endocrine disorder affecting reproductive-age women and is closely associated with metabolic disturbances such as overweight and insulin resistance. More than 50% of women with PCOS are overweight, which exacerbates ovulatory dysfunction and increases androgen levels. Insulin resistance, found in approximately 50% of PCOS patients—even those with normal body weight—triggers hyperinsulinemia that stimulates androgen production and suppresses ovulation. This study aims to analyze the contribution of overweight and insulin resistance to the development of PCOS through a literature review approach. Scientific articles were retrieved from databases such as PubMed and Google Scholar, focusing on publications from the last five years. The findings indicate that overweight and insulin resistance mutually reinforce hormonal and ovulatory dysfunction typical in PCOS patients. Recent studies show that higher body mass index (BMI) and elevated HOMA-IR levels are strongly associated with menstrual irregularities, hyperandrogenism, and reduced quality of life. In conclusion, overweight and insulin resistance are two major contributing factors to PCOS pathogenesis and influence reproductive success. Clinical management should consider a comprehensive approach targeting both factors through lifestyle interventions and pharmacological therapy.
AKTIVITAS ANTIJAMUR KOMBINASI EKSTRAK ETANOL DAUN MANGGA BACANG (MANGIFERA FOETIDA L.) DAN DAUN BIDARA (ZIZIPHUS MAURITIANA L.) TERHADAP CANDIDA ALBICANS Dini Mardhiyani; Kony Putriani
Jurnal Ilmiah Manuntung: Sains Farmasi Dan Kesehatan Vol. 7 No. 2 (2021): Jurnal Ilmiah Manuntung: Sains Farmasi Dan Kesehatan
Publisher : Sekolah Tinggi Ilmu Kesehatan Samarinda

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.51352/jim.v7i2.501

Abstract

Along with increasing life expectancy, the community tries to find solutions to health problems. One of the health problems that occur in humans is caused by fungi. Candida albicans is one of the fungi that can be found in humans. Candida albicans are normal flora in the vagina, digestive tract, and oral cavity. Nevertheless, it can change into a pathogen and cause changes in the host. Based on compound contained in leaf of mango bacang and leaf of bidara, they have antifungal effect. This study aims to determine the antifungal activity of single ethanol extract of mango bacang leaves and bidara leaves with a combination of bidara leaves ethanol extract and ethanol extract of mango bacang leaves against Candida albicans. The method of this study begins with collecting mango bacang leaves and bidara leaves then extracted maceration with ethanol solvents. The antifungal activity is tested with the disk diffusion method using potato dextrose media. Based on the results of the hypothesis test obtained a significance value of 0.010 <0.05, there was a difference in the diameter of the inhibition zone against the growth of Candida albicans due to a single giving and variations in the combination of ethanol mango bacang leaves and bidara leaves ethanol extract. Extract single antifungal activity after combined experienced a minimum increase of 1.2%. The conclusion of this study shows that the combination of ethanol extract of bacang mango leaves with bidara leaves ethanol extract has a larger inhibiting zone than a single extract and shows the synergy effect. The use of bacang mango leaves as anti-fungal is recommended in combination with bidara leaves.
Co-Authors Diana Resky Eva Oktariani Islami, Deri Janu, Juwana Juwana janu Kony Putriani Melinda Rehulina Pratiwi, Denia