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All Journal INDONESIAN JOURNAL OF MEDICAL LABORATORY SCIENCE AND TECHNOLOGY Jurnal EduHealth PharmaCine: Journal of Pharmacy, Medical and Health Science
Vina Luthfiana Hasna
Universitas Singaperbangsa Karawang
Biochemistry, Genetics & Molecular Biology Chemistry Dentistry Health Professions Immunology & microbiology Medicine & Pharmacology Public Health Social Sciences Veterinary

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Standardization Methods for the Determination of Curcumin in Turmeric and Its Anticancer Activities : A Review Imel Ramelia Hudaya; Vina Luthfiana Hasna; Febi Febriani Hasanah; Khamairah Azzahrawaani Hermawan; Vriezka Mierza
Jurnal EduHealth Vol. 14 No. 01 (2023): Jurnal eduHealth, Periode Januari-Maret, 2023
Publisher : Sean Institute

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (243.465 KB)

Abstract

Cancer is one of the deadliest diseases in the world. Indonesia is a country with cancer rates that ranks 8th in Southeast Asia. Cancer that has the highest number of sufferers in Indonesian men is lung cancer, as much as 19.4 per 100,000 population, with an average death rate of 10.9 per 100,000. Meanwhile, for women, breast cancer is the highest cancer incidence rate, which is 42.1 per 100,000 population, with an average death rate of 17 per 100,000 population. Although chemotherapy remains a highly efficient way to treat cancer, it is the drawbacks related to its side effects that are often feared. Natural products such as plants are more beneficial for improving treatment results because they are safe and can minimize side effects on healthy cells. Herbal plants that are often associated with anticancer drugs are turmeric. Currently, several standardized methods have been developed to analyze curcumin in turmeric, and from these methods, there are advantages and disadvantages of each method. Therefore, selecting the analytical method is very important to get better results.
A Narrative Literature Review : Is Cosmetic Breast Implants Safe for Women? Vina Luthfiana Hasna; Salman Salman; Indah Laily Hilmi
Jurnal EduHealth Vol. 14 No. 01 (2023): Jurnal eduHealth, Periode Januari-Maret, 2023
Publisher : Sean Institute

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In order to maintain, obtain, and take care of beauty from day to day, cosmetics have always played an important role in women’s lives to overcome these problems. The use of cosmetics used by women is based on a beauty standard which of course varies in each country. The most common beauty standards are physical beauty, character beauty (inner beauty), white skin, and proportional body sizes. The existence of these beauty standards sometimes makes women feel dissatisfied with their physique, even for some people, changing their physique or changing body size by performing plastic surgery is a natural thing. One of the most common plastic surgery procedures worldwide is breast augmentation through implants. The frequency of surgical procedures requiring breast implants in recent years has continued to increase. In the 1980s, when the third generation of silicone implants were introduced, widespread public health concerns began to emerge about the adverse effects of breast implants. The purpose of this review article is to discuss the safety of breast implants in women based on the relevant scientific evidence. Although not all symptoms and effects of breast implants can appear in all users of breast implants, this review can help women to make the right decision regarding breast implant procedures.
Metode Isolasi Metabolit Sekunder pada Bahan Bahari Makro Alga Vina Luthfiana Hasna; Nisa Alifia Zahra; Imel Ramelia Hudaya; Herdiana Verliani; Febi Febriani Hasanah
PharmaCine : Journal of Pharmacy, Medical and Health Science Vol. 2 No. 1 (2021): PharmaCine : Journal of Pharmacy, Medical and Health Science
Publisher : Bachelor of Pharmacy Study Program, Faculty of Health Sciences, Universitas Singaperbangsa Karawang

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.35706/pc.v2i1.5580

Abstract

Indonesia merupakan negara yang kaya akan biota laut, salah satunya adalah makro alga. Pembuatan review artikel ini dilakukan untuk menambah pengetahuan tentang ilmu bahari khususnya dalam isolasi metabolit sekunder pada makro alga. Kelompok makro alga atau lebih dikenal dengan sebutan rumput laut merupakan tumbuhan tingkat rendah yang memproduksi senyawa metabolit sekunder. Isolasi pada makro alga menunjukkan adanya senyawa metabolit sekunder yang terkandung (flavonoid, steroid, terpenoid, alkaloid, fenol, saponin). Metode yang digunakan pada review ini merupakan suatu tinjauan literatur (literatur review) terhadap lima jurnal dan berdasarkan teori-teori yang relevan. Adapun untuk mendapatkan ekstrak sampel dilakukan teknik yang sama yaitu maserasi menggunakan pelarut yang sesuai karakteristik zat yang akan diisolasi selama 1-3 hari. Sedangkan untuk mengisolasi senyawa metabolit sekunder digunakan teknik kromatografi kolom, kromatografi gas-spektometri massa (GC-MS) dan kromatografi lapis tipis (KLT).
Molecular identification and antibacterial activity of endophytic bacteria from Bambusa vulgaris leaves as antibacterial potential against phatogenic microoganism Jekmal Malau; Vriezka Mierza; Munir Alinu Mulki; Lestari Mahardika Urbaningrum; Vina Luthfiana Hasna; Priscinya Christiana Debora
JURNAL INDONESIA DARI ILMU LABORATORIUM MEDIS DAN TEKNOLOGI Vol 7 No 2 (2025): From Natural Compounds to Disease Mechanisms: An Integrated Research Outlook
Publisher : Universitas Nahdlatul Ulama Surabaya

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.33086/ijmlst.v7i2.6538

Abstract

The increasing prevalence of antibiotic-resistant bacteria poses a critical global health concern, necessitating the exploration of novel antibacterial solutions. Endophytic bacteria, which colonize plant tissues without causing harm, have gained attention as potential sources of bioactive metabolites. This study aimed to isolate and characterize endophytic bacteria from Bambusa vulgaris leaves and evaluate their antibacterial potential against pathogenic microorganisms. Leaf samples were collected from Bekasi, West Java, and subjected to a surface sterilization process prior to bacterial isolation. A total of 12 bacterial strains were successfully obtained and screened for antibacterial activity against Bacillus subtilis, Propionibacterium acnes, Pseudomonas aeruginosa, and Staphylococcus epidermidis using the agar well diffusion assay. Three isolates exhibited notable inhibitory activity, with P8 demonstrating the strongest antibacterial effects against B. subtilis, P. acnes, and S. epidermidis. The two most potent isolates, P8 and K3, were characterized via 16S rRNA gene sequencing. Genomic DNA extraction was performed, followed by Polymerase Chain Reaction (PCR) amplification using the universal primers 27F (5′-AGAGTTTGATYMTGGCTCAG-3′) and 1492R (5′-GGTTACCTTGTTACGACTT-3′). Sequencing and The Basic Local Alignment Search Tool (BLAST) analysis confirmed that isolate P8 exhibited 100% similarity to B. subtilis strain LZH-H1, whereas isolate K3 shared 99.85% similarity with Pantoea stewartii subsp. indologenes strain SR2-12. These findings suggest that endophytic bacteria from B. vulgaris endohytic bacteria hold promise as potential sources of antibacterial compounds. Further research is necessary to purify and characterize these bioactive metabolites for potential pharmaceutical applications.
Co-Authors Febi Febriani Hasanah Herdiana Verliani Imel Ramelia Hudaya Imel Ramelia Hudaya Indah Laily Hilmi Jekmal Malau Khamairah Azzahrawaani Hermawan Lestari Mahardika Urbaningrum Munir Alinu Mulki Nisa Alifia Zahra Priscinya Christiana Debora Salman Salman Vriezka Mierza