Risna Risna
Sekolah Tinggi Ilmu Kesehatan Jayapura

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Uji Aktivitas Antibakteri Ekstrak Etanol Daun Matoa (Pometia Pinnata J. R & G.Forst.) terhadap Pertumbuhan Staphylococcus Aureus dan Escherichia Coli Risna Risna
Jurnal Keperawatan Silampari Vol 6 No 2 (2023): Jurnal Keperawatan Silampari
Publisher : Institut Penelitian Matematika, Komputer, Keperawatan, Pendidikan dan Ekonomi (IPM2KPE)

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (300.648 KB) | DOI: 10.31539/jks.v6i2.4725

Abstract

This study aims to determine the antibacterial activity, effective concentration, and secondary metabolites in the ethanol extract of matoa left against the test bacteria Staphylococcus aureus and Escherichia coli. The research method extracts matoa leaf samples by maceration using 70% ethanol solvent, testing the antibacterial activity using the paper disk diffusion method. The results of the antibacterial activity test were then analyzed using the One way ANOVA method. The results showed that the diameter of the inhibition zone of the ethanol extract of matoa leaves on the growth of Staphylococcus aureus appeared to have a clear area at a concentration of 1%, 1.5%, and 2%, respectively, of 12.88 mm, 13.15 mm, 11.36 mm. In comparison, the results of measuring the diameter of the inhibition zone of the ethanol extract matoa leaf on the growth of Escherichia coli bacteria were seen to have a clear area at a concentration of 1%, 1.5%, and 2% of 9.5 mm, 10.23 mm, 12.1 mm respectively. This activity is thought to be due to the effects of alkaloid compounds, flavonoids, tannins, saponins, and steroids in the ethanol extract of matoa leaves. Based on the ANOVA test, a significance value of 0.000 <0.05 was obtained, so the results were significant. In conclusion, there are substantial differences in the use of various concentrations of matoa leaf extract on the growth of Staphylococcus aureus and Escherichia coli bacteria. Keywords: Antibacterial Activity, Matoa Leaves, Secondary Metabolites
FORMULASI DAN EVALUASI KRIM EKSTRAK DAUN KETEPENG CINA (CASSIA ALATA L.) DENGAN VARIASI KONSENTRASI BASIS ASAM STEARAT DAN TRIETANOLAMIN Risna Risna; Gabriela Litaay
Journal of Nursing and Health Vol. 9 No. 4 (2024): Journal of Nursing and Health
Publisher : Yakpermas Press

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.52488/jnh.v9i4.440

Abstract

Ketepeng Cina (Cassia alata L.) merupakan tumbuhan yang hidup liar di ekosistem hutan hujan tropis yang lembab yaitu di area pinggiran rawa hingga di tepi jalan, tersebar luas di Pulau Papua dan disebut “Daun Kaskado” karena dimanfaatkan bagian daunnya sebagai obat tradisional untuk mengobati penyakit “Kaskado” atau penyakit tinea imbrikata. Tujuan penelitian ini adalah untuk memformulasikan dan mengevaluasi krim ekstrak daun ketepeng cina (Cassia alata L) dengan variasi konsentrasi basis asam starat dan trietanolamin, Pembiuatan ekstrak ketepeng cina dilakukan dengan metode maserasi menggunakan pelarut etanol 70%. Formulasi sediaan krim ketepeng cina dengan memvariasikan konsentrasi asam sterat dan trietanolamin sebanyak 3 variasi konsentrasi. Berdasarkan hasil penelitian yang dilakukan dapat disimpulkan bahwa ekstrak daun ketepeng cina dapat diformulasikan menjadi sediaan krim menggunakan basis asam stearate dan trietanolamin dan menghasilkan sifat fisik krim yang baik.