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Uji Aktivitas Antibakteri Ekstrak Etanol Daun Matoa (Pometia Pinnata J. R & G.Forst.) terhadap Pertumbuhan Staphylococcus Aureus dan Escherichia Coli Risna Risna
Jurnal Keperawatan Silampari Vol 6 No 2 (2023): Jurnal Keperawatan Silampari
Publisher : Institut Penelitian Matematika, Komputer, Keperawatan, Pendidikan dan Ekonomi (IPM2KPE)

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (300.648 KB) | DOI: 10.31539/jks.v6i2.4725

Abstract

This study aims to determine the antibacterial activity, effective concentration, and secondary metabolites in the ethanol extract of matoa left against the test bacteria Staphylococcus aureus and Escherichia coli. The research method extracts matoa leaf samples by maceration using 70% ethanol solvent, testing the antibacterial activity using the paper disk diffusion method. The results of the antibacterial activity test were then analyzed using the One way ANOVA method. The results showed that the diameter of the inhibition zone of the ethanol extract of matoa leaves on the growth of Staphylococcus aureus appeared to have a clear area at a concentration of 1%, 1.5%, and 2%, respectively, of 12.88 mm, 13.15 mm, 11.36 mm. In comparison, the results of measuring the diameter of the inhibition zone of the ethanol extract matoa leaf on the growth of Escherichia coli bacteria were seen to have a clear area at a concentration of 1%, 1.5%, and 2% of 9.5 mm, 10.23 mm, 12.1 mm respectively. This activity is thought to be due to the effects of alkaloid compounds, flavonoids, tannins, saponins, and steroids in the ethanol extract of matoa leaves. Based on the ANOVA test, a significance value of 0.000 <0.05 was obtained, so the results were significant. In conclusion, there are substantial differences in the use of various concentrations of matoa leaf extract on the growth of Staphylococcus aureus and Escherichia coli bacteria. Keywords: Antibacterial Activity, Matoa Leaves, Secondary Metabolites
FORMULASI DAN EVALUASI KRIM EKSTRAK DAUN KETEPENG CINA (CASSIA ALATA L.) DENGAN VARIASI KONSENTRASI BASIS ASAM STEARAT DAN TRIETANOLAMIN Risna Risna; Gabriela Litaay
Journal of Nursing and Health Vol. 9 No. 4 (2024): Journal of Nursing and Health
Publisher : Yakpermas Press

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.52488/jnh.v9i4.440

Abstract

Ketepeng Cina (Cassia alata L.) merupakan tumbuhan yang hidup liar di ekosistem hutan hujan tropis yang lembab yaitu di area pinggiran rawa hingga di tepi jalan, tersebar luas di Pulau Papua dan disebut “Daun Kaskado” karena dimanfaatkan bagian daunnya sebagai obat tradisional untuk mengobati penyakit “Kaskado” atau penyakit tinea imbrikata. Tujuan penelitian ini adalah untuk memformulasikan dan mengevaluasi krim ekstrak daun ketepeng cina (Cassia alata L) dengan variasi konsentrasi basis asam starat dan trietanolamin, Pembiuatan ekstrak ketepeng cina dilakukan dengan metode maserasi menggunakan pelarut etanol 70%. Formulasi sediaan krim ketepeng cina dengan memvariasikan konsentrasi asam sterat dan trietanolamin sebanyak 3 variasi konsentrasi. Berdasarkan hasil penelitian yang dilakukan dapat disimpulkan bahwa ekstrak daun ketepeng cina dapat diformulasikan menjadi sediaan krim menggunakan basis asam stearate dan trietanolamin dan menghasilkan sifat fisik krim yang baik.
Pharmaceutical Service Standards at Inpatient Health Center Farhan Imba; Nawang Wulan Nago Pita Sari; Ferdinta D. Setyawan; Yance R Rainuny; Risna Risna
Indonesian Journal of Global Health Research Vol 7 No 1 (2025): Indonesian Journal of Global Health Research
Publisher : GLOBAL HEALTH SCIENCE GROUP

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.37287/ijghr.v7i1.5512

Abstract

Pharmaceutical services are direct and accountable assessments of patients' pharmaceutical needs, with the objective of enhancing their quality of life by achieving positive results. The objective of this investigation is to investigate pharmaceutical services in the Kerem district in accordance with the Regulation of the Minister of Health No 2012 and Regulation No 74 of 2016 regarding the requirements for pharmaceutical services in medical centers. A cross-sectional methodology is employed in this descriptive study. The data obtained via surveys and checklists was derived from direct observation at Puskesmas pharmacies during the presence of pharmacists or pharmacy technicians. The collected data were analysed in conjunction with the established standards in the literature and evaluated using the Chi-Square test. The study's findings indicate that the Kerom Regency Health Centre attained a score of 64 in the execution of pharmaceutical service criteria. The category exhibiting the greatest level of satisfaction was the satisfied category, with a percentage of 74.7%. The chi-square test is employed in statistical analysis to examine the correlation between patient demographic variables, including age, gender, occupation, and patient satisfaction. This study yielded statistically significant results with a P-value less than 0.05.
Evaluation of Antibiotic use with the ATC/DDD Method and DU 90% on Respiratory Tract Infection Patients Nawang Wulan Nago Pita Sari; Farhan Imba; Risna Risna; Gabriela Welma Litaay
Indonesian Journal of Global Health Research Vol 7 No 1 (2025): Indonesian Journal of Global Health Research
Publisher : GLOBAL HEALTH SCIENCE GROUP

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.37287/ijghr.v7i1.5513

Abstract

Drug availability is one of the factors in the success of pharmaceutical services at the community health center (Puskesmas) as a Primary Health Facility (FKTP). The aim of this study was to determine the quantity of antibiotic use using the ATC/DDD method and DU 90%, as well as the percentage of antibiotic prescription conformity with the National Formulary (Fornas). The method used was an observational cross-sectional study with a descriptive approach. Data were collected retrospectively for the period of May to October 2024 at Khomba Health Center, Jayapura Regency. The results of this study indicate that the most commonly used antibiotic was Amoxicillin with a value of (1996.36 DDD/1,000/year). The antibiotic included in the DU 90% segment was Amoxicillin, and the level of prescription conformity with the National Formulary (Fornas) reached 100%.