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Journal : SOCIAL CLINICAL PHARMACY INDONESIA JOURNAL

The Relationship Of Allergies With The Covid-19 Booster Vaccine In Communities In The Taman Sari District Area, West Jakarta In 2022 Astiani, Rangki; Luthfiana, Farisa; Ramatillah, Diana Laila; Vivian, Maria
SOCIAL CLINICAL PHARMACY INDONESIA JOURNAL Vol 8, No 2 (2023)
Publisher : Universitas 17 Agustus 1945 Jakarta

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.52447/scpij.v8i2.7449

Abstract

In the era of the Covid-19 pandemic, various preventive measures are needed against the transmission of the corona virus, namely by wearing masks, washing hands, staying away from crowds, avoiding physical contact and byincreasing the body's immune system through vaccination, which is one of the prevention measures to reduce the transmission/transmission of Covid-19. 19 so as to reduce morbidity and mortality. The research was conducted to obtain an overview of the use of vaccination and the relationship between allergies to Booster vaccines in the Taman Sari Village Community, West Jakarta in 2022. The type of research used in this research is quantitative, namely using a cross-sectional analytical descrip- tive method. The population in this study was the people of Taman Sari Village, West Jakarta and the sample was taken as many as 124 people using a sampling technique, namely accidental sampling. From this research, results were obtained regarding the existence of a relationship between the Covid-19booster vaccine and allergies in the Taman Sari sub-district community north Jakarta.
Clinical Pharmacy Services at The Central Public Hospital "X" Luthfiana, Farisa; Astiani, Rangki; piter, piter; Sukartiningsih, Yulita
SOCIAL CLINICAL PHARMACY INDONESIA JOURNAL Vol 8, No 2 (2023)
Publisher : Universitas 17 Agustus 1945 Jakarta

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.52447/scpij.v8i2.7440

Abstract

Background: Pharmaceutical service is a direct and responsible service to patients related to pharmaceutical preparations with the aim of achieving definite results to improve the patient's quality of life.Objective: The aim is to find out how clinical pharmacy services are at “X” Hospital with eleven clinical pharmacyservice indicators based on Minister of Health Regulation Number 72 of 2016.Methods: The method used is descriptive, which aims to obtain a realistic and objective picture of pharmaceuticalservices at “X” Center General Hospital.Results: The results of the study found that eleven indicators of clinical pharmacy services were Assessment and Prescription Services, Tracing Drug Use History, Drug Reconciliation, Drug Information Services (PIO), Counseling, Visitation, Drug Therapy Monitoring (PTO), Drug Side Effects Monitoring (MESO), Evaluation Medication Use(EPO), Dispensing of Sterile Preparations, and Monitoring Blood Drug Levels (PKOD) have been carried out properly in accordance with Minister of Health Regulation No. 72 of 2016, except for PKOD because there is no request from the doctor or pharmacist's initiative to do so.
DRUG THERAPY IN PATIENTS WITH GRADE 4 DEXTRA HIP OSTEOARTHRITIS WITH COMORBID HYPERTENSION AND TYPE 2 DIABETES MELLITUS Astiani, Rangki; Piter, Piter; Anggraeni, Ria; Luthfiana, Farisa; Sari, Dini Permata; Ramatillah, Diana Laila; Khan, Khasif
SOCIAL CLINICAL PHARMACY INDONESIA JOURNAL Vol 10, No 2 (2025)
Publisher : Universitas 17 Agustus 1945 Jakarta

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.52447/scpij.v10i2.8977

Abstract

Osteoarthritis (OA) is a chronic degenerative disease that affects the joints, especially heavy joints such as the knees and hips. OA often causes chronic pain and limited mobility, which is even more complex when accompanied by comorbid hypertension and type 2 diabetes mellitus. These comorbidities increase the risk of pharmacotherapy side effects and drug interactions, requiring a multidisciplinary approach and careful clinical pharmacy monitoring. The purpose of this report is to review the pharmacotherapy management of grade 4 OA Hip Dextra with comorbid HT and DMT2, assessing the safety, effectiveness, and role of clinical pharmacists in therapy optimization. A retrospective case study was conducted by analyzing the patient's medical records, including anamnesis, physical examination, laboratory, pharmacological therapy, and clinical response. The analysis was conducted based on the national guidelines of the Indonesian Ministry of Health, the 2021 National Formulary, PERKENI 2023, and PAPDI 2021. The patient was given combination therapy of NSAIDs, analgesics, prophylactic antibiotics, muscle relaxants, gastric protection, and supplementation for anemia. Therapeutic adjustments were made according to the patient's response and laboratory parameters. Clinical pharmacy monitoring ensures pain control, mobility, hemoglobin, and blood sugar. A multidisciplinary approach based on national guidelines has been shown to improve the safety and effectiveness of OA therapy with multiple comorbidities.
Resistensi Clopidogrel pada Pasien Penyakit Jantung Koroner di Asia Tenggara: Sebuah Narrative Review Luthfiana, Farisa
SOCIAL CLINICAL PHARMACY INDONESIA JOURNAL Vol 10, No 1 (2025)
Publisher : Universitas 17 Agustus 1945 Jakarta

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.52447/scpij.v10i1.9135

Abstract

Clopidogrel is a commonly used antiplatelet agent for the prevention of thrombotic events in patients with coronary artery disease (CAD), particularly in acute coronary syndrome and after percutaneous coronary intervention. However, interindividual variability in clopidogrel response, known as clopidogrel resistance or high on-treatment platelet reactivity (HPR), is associated with increased risks of adverse cardiovascular outcomes. This issue is especially relevant in Southeast Asia, where genetic and clinical factors may influence drug response.Objective: This narrative review aims to summarize current evidence regarding the mechanisms, prevalence, and clinical implications of clopidogrel resistance in patients with coronary artery disease in Southeast Asia. Methods: A narrative review of peer-reviewed literature was conducted focusing on clopidogrel resistance, platelet reactivity, CYP2C19 genetic polymorphisms, and cardiovascular outcomes in Asian and Southeast Asian populations. Results:Evidence indicates that CYP2C19 loss-of-function alleles are highly prevalent in Southeast Asia, resulting in a substantial proportion of patients classified as intermediate or poor metabolizers. These genetic variants are associated with reduced clopidogrel activation, increased platelet reactivity, and a higher risk of major adverse cardiovascular events, including stent thrombosis and recurrent myocardial infarction. Non-genetic factors such as diabetes mellitus, drug–drug interactions, and medication non-adherence further contribute to clopidogrel resistance. Pharmacogenetic-guided antiplatelet therapy and the use of alternative P2Y12 inhibitors, such as ticagrelor or prasugrel, have shown potential to improve clinical outcomes. Conclusion:Clopidogrel resistance represents a significant clinical challenge among patients with coronary artery disease in Southeast Asia. Integration of pharmacogenetic-guided strategies may enhance the effectiveness of antiplatelet therapy in this region.