Inayah Inayah
Department Of Pharmacology, Faculty Of Medicine, Universitas Riau

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EOSINOPHILS PROFILE AND LUND-MACKAY SCORE OF NASAL POLYPS IN ARIFIN ACHMAD HOSPITAL, RIAU PROVINCE Yolazenia Yolazenia; Inayah Inayah; Febri Romaito Romaito; Retni Tri Handayani; Novisa Dwi Utami
Berkala Kedokteran Vol 18, No 1 (2022)
Publisher : Fakultas Kedokteran Universitas Lambung Mangkurat

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (212.457 KB) | DOI: 10.20527/jbk.v18i1.12820

Abstract

Abstract: Theories suggest that nasal polyps occur as a result of chronic inflammation of the nasal and sinus mucosa. Eosinophils are the main inflammatory cells found in nasal polyp tissue. The severity of nasal polyps can be seen from the CT Scan of the Paranasal Sinus (PNS) using the Lund-Mackay score. The purpose of this study was to determine the description of the eosinophil count of nasal polyp tissue and the Lund-Mackay score of CT Scan PNS of nasal polyps patients in Arifin Achmad Hospital, Riau Province. Examination of the eosinophil count was carried out microscopically using histopathological preparations of nasal polyp tissue with semiquantitative assessment, and Lund-Mackay score was assessed from the CT Scan of the PNS. From the 14 samples collected, there were 8 men (57.1%) more than 6 women (42.9%) with an average age of 30.43 ± 17.36 years old. Eosinophil counts were obtained in 5  (35,7%) samples 1/2+,  5 (35.7%) samples 1+, and negative in 4 samples (28,6%). While the Lund-Mackay score obtained an average value of 10.21 ± 6.87 with a low category in 11 (78.6%) and high in 3 (21.4%) samples. Patients with high Lund-Mackay scores tend to have higher eosinophil counts which reflect a more severe degree of disease severity in nasal polyps.Keywords: Eosinophil; Lund-Mackay Score; Nasal polyp; Paranasal sinus
Effectiveness of Vitamin D Suplementation in Pregnant Women with Vitamin D Deficiency to Improved Fetal Biometry Donel S.; Ruza Prima Rustam; Inayah Inayah; M. Yulis Hamidy; Ratu Astuti Dwi Putri; Machyuddin T.M Pangaribuan; Ahmad Fahruddin; Maya Savira
Indonesian Journal of Obstetrics & Gynecology Science Volume 6 Nomor 1 Maret 2023
Publisher : Dep/SMF Obstetri & Ginekologi Fakultas Kedokteran Universitas Padjadjaran

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.24198/obgynia/v6n1.461

Abstract

Objective: The aim of this study was to determine the effect and effectiveness of vitamin D on fetal biometry.Method: This study was a Quantitative Study of two quasi-experimental groups. The research was conducted in Rupat District, Bengkalis Regency, Riau Province from June 2022 to August 2022. The research sample was pregnant women with vitamin D deficiency who were divided into an intervention group of 20 subjects and a control group of 20 subjects.Results: Examination of vitamin D levels in pregnant women and examination of fetal biometry was carried out. Then given a 1000 IU vitamin D supplement to pregnant women with vitamin D deficiency levels, re-evaluated after 3 months vitamin D levels in pregnant women and re-measured fetal biometry. There were significant differences in Fetal Biometrics between the pre-Intervention and post-Intervention studies in the intervention group with p=0.001. The intervention group also showed that there was an increase in the proportion of Normal Biometrics from 8 subjects before the intervention compared to 13 subjects after 3 months of vitamin D supplementation interventionConclusion: Vitamin D supplementation for 3 months in pregnant women with Vitamin D deficiency is proven to improve fetal health through Fetal Biometry examination.Efektivitas Suplemen Vitamin D dalam Meningkatkan Biometri Janin pada Wanita Hamil dengan Defisiensi Vitamin DAbstrakTujuan: Studi ini bertujuan mengetahui dampak dan efektivitas vitamin D terhadap biometri janin.Metode: Studi kuantitatif ini mengunakan dua grup dengan pendekatan kuasi-eksperimental. Penelitian ini dilaksanakan di Rupat, Kabupaten Bengkalis, Provinsi Riau dari Juni 2022 hingga Agustus 2022. Sampel penelitian ini adalah Wanita hamil dengan defisiensi vitamin D yang dibagi menjadi grup intervensi sebanyak 20 orang dan grup kontrol sebanyak 20 orang.Hasil: Dilakukan pengukuran kadar vitamin D pada Wanita hamil dan biometri janin. Pada grup intervensi diberikan suplementasi vitamin D 1000IU dan dievaluasi kembali kadar vitamin D setelah tiga bulan dan dilakukan kembali biometri janin. Terdapat perbedaan signifikan pada biometri janin sebelum dan sesudah intervensi dengan p=0.001. Grup intervensi juga menunjukkan peningkatan proprorsi biometri normal dari 8 orang menjadi 13 orang setelah tiga bulan suplementasi vitamin DKesimpulan: Suplementasi vitamin D selama tiga bulan pada Wanita hamil dengan defisiensi vitamin D terbukti membantu kesehatan janin melalui pemeriksaan biometri janin.Key words: Biometri, Defisiensi Vitamin D, Kehamilan