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All Journal Jurnal Ilmu Kedokteran (Journal of Medical Science) Berkala Kedokteran Jurnal Kesehatan Melayu BERDIKARI : Jurnal Inovasi dan Penerapan Ipteks Jurnal Epidemiologi Kesehatan Komunitas Jurnal Kreativitas PKM Oto Rhino Laryngologica Indonesiana

Yolazenia Yolazenia

Bagian Telinga Hidung Tenggorok - Bedah Kepala Leher Fakultas Kedokteran Universitas Riau

Author-ID : 3641664

Biochemistry, Genetics & Molecular Biology Computer Science & IT Dentistry Education Health Professions Immunology & microbiology Medicine & Pharmacology Nursing Public Health

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Articles

Biofilm Bakteri pada Penderita Rinosinusitis Kronis Dolly Irfandy; Yolazenia Yolazenia; Bestari Jaka Budiman; Dolly Irfandy
Jurnal Kesehatan Melayu Vol 1, No 2 (2018): April 2018
Publisher : Fakultas Kedokteran Universitas Riau

Banyak dilaporkan kegagalan pengobatan pada rinosinusitis kronis (RSK) disebabkan resistensi terhadap antibiotik. Beberapa penelitian menunjukkan bahwa biofilm bakteri berperan penting pada etiologi dan persistensi dari RSK. Penulisan tinjauan pustaka ini adalah untuk mengetahui implikasi biofilm bakteri pada penderita RSK. Rinosinusitis kronis adalah penyakit inflamasi mukosa hidung dan sinus paranasal yang berlangsung dalam waktu lebih dari 12 minggu. Biofilm adalah suatu struktur komunitas sel-sel bakteri yang ditutupi oleh matriks polimer yang dihasilkan sendiri dan menempel pada permukaan. Berbagai penelitian menunjukkan terdapatnya biofilm bakteri pada mukosa sinonasal penderita RSK dan berhubungan dengan resistensi terhadap pengobatan dengan antibiotika. Berbagai pemeriksaan untuk mendeteksi biofilm yaitu Scanning Electron Microscopy (SEM), Transmission Electron Microscopy (TEM), Confocal Scanning Laser Microscopy (CSLM), modifikasi Calgary Biofilm Device Assay, Tube Method dan Congo Red Agar Method. Beberapa terapi potensial untuk mengatasi biofilm pada RSK sedang berkembang.

Gambaran Kepadatan Tungau Debu Rumah Sebagai Pencetus Rinitis Alergi pada Anak Panti Asuhan Pekanbaru Yolazenia Yolazenia; Harianto Harianto; Iqbal Teguh Riady
Jurnal Ilmu Kedokteran Vol 13, No 1 (2019): Jurnal Ilmu Kedokteran
Publisher : Fakultas Kedokteran Universitas Riau

Allergic rhinitis should be considered as a serious condition because it can affect the quality of life of patients. In many cases, the most common allergen is house dust mites (HDM). The purpose of this study was to describe the density of house dust mites as triggers of allergic rhinitis in Pekanbaru orphanage children. This is a descriptive study with a cross sectional approach. Data obtained from interviews using the modified International Study of Asthma and Allergies of Childhood (ISAAC) questionnaire to know the allergic rhinitis status and examination of house dust samples to identify HDM in the parasitology laboratory. Sampling was carried out in 4 orphanages Pekanbaru. Allergic rhinitis symptoms were experienced by 81.2% of children in the orphanages and HDM was found with the mean density 9.11/g of dust. HDM was found in all four orphanages and was found to have a high incidence of allergic rhinitis.

EOSINOPHILS PROFILE AND LUND-MACKAY SCORE OF NASAL POLYPS IN ARIFIN ACHMAD HOSPITAL, RIAU PROVINCE Yolazenia Yolazenia; Inayah Inayah; Febri Romaito Romaito; Retni Tri Handayani; Novisa Dwi Utami
Berkala Kedokteran Vol 18, No 1 (2022)
Publisher : Fakultas Kedokteran Universitas Lambung Mangkurat

Abstract: Theories suggest that nasal polyps occur as a result of chronic inflammation of the nasal and sinus mucosa. Eosinophils are the main inflammatory cells found in nasal polyp tissue. The severity of nasal polyps can be seen from the CT Scan of the Paranasal Sinus (PNS) using the Lund-Mackay score. The purpose of this study was to determine the description of the eosinophil count of nasal polyp tissue and the Lund-Mackay score of CT Scan PNS of nasal polyps patients in Arifin Achmad Hospital, Riau Province. Examination of the eosinophil count was carried out microscopically using histopathological preparations of nasal polyp tissue with semiquantitative assessment, and Lund-Mackay score was assessed from the CT Scan of the PNS. From the 14 samples collected, there were 8 men (57.1%) more than 6 women (42.9%) with an average age of 30.43 ± 17.36 years old. Eosinophil counts were obtained in 5 (35,7%) samples 1/2+, 5 (35.7%) samples 1+, and negative in 4 samples (28,6%). While the Lund-Mackay score obtained an average value of 10.21 ± 6.87 with a low category in 11 (78.6%) and high in 3 (21.4%) samples. Patients with high Lund-Mackay scores tend to have higher eosinophil counts which reflect a more severe degree of disease severity in nasal polyps.Keywords: Eosinophil; Lund-Mackay Score; Nasal polyp; Paranasal sinus

Gambaran Profil dan Infeksi Cacing Usus pada Pekerja di Tiga Rumah Potong Hewan Provinsi Riau Esy Maryanti; Yola Zenia; Afrinaldi Aldi; Fadly Mulia; Mislindawati Linda
Jurnal Epidemiologi Kesehatan Komunitas Vol 6, No 1: Februari 2021
Publisher : Master of Epidemiology, School of Postgraduate Studies, Diponegoro University, Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.14710/jekk.v6i1.9337

Background: Intestinal worm infestation is still a health problem in Indonesia that is often neglected. This disease is chronic in nature and is strongly influenced by factors of environmental hygiene and sanitation. Slaughterhouses are places where animals in the form of cows, goat/ sheep and pigs are slaughtered to be distributed to meat sellers or to reataurants. This study aims to determine the profil description and incidence of intestinal worm infestations in workers in three slaughterhouses in Riau Province.Methods: This study was a cross-sectional descriptive study in August – October 2020 in three slaughterhouses in Riau Province ( Pekanbaru, Duri and Dumai city). Stool examination was carried out using the Kato Katz Method at the Parasitology Laboratory Medical Faculty, Universitas Riau. Result: Do A total 37 workers who were examined found 35 men, age range 21 – 30 yo as much as 38% with latest education 46% was high school, length of work 1 – 5 years as much as 57% and as much as 41% have normal nutriotional status. Six workers found positive for intestinal worm infections (16%), there were three hookworm infections and one each to Trichuris trichiura, Oxyuris vermicularis and Hymenolepis diminuta.Conclusion : There were still intestinal worm infections among workers in the three slaughterhouses. Intestinal worm infection usually occurs in children and rarely occurs in adults and if it occurs in adults this may be due to poor hygiene and sanitation of the slaughterhouse workers.

Peran biofilm bakteri terhadap derajat keparahan rinosinusitis kronis berdasarkan skor Lund-Mackay Dolly Irfandy; Y Yolazenia; Bestari Jaka Budiman; Effy Huriyati; Aziz Djamal; Rizanda Machmud; Dolly Irfandy
Oto Rhino Laryngologica Indonesiana Vol 47, No 2 (2017): Volume 47, No. 2 July - December 2017
Publisher : PERHATI-KL

Latar belakang: Rinosinusitis kronis (RSK) adalah penyakit inflamasi mukosa hidung dan sinus paranasal yang berlangsung lebih dari 12 minggu. Berbagai kondisi telah dikaitkan dengan patogenesis penyakit ini, seperti infeksi bakteri, jamur, superantigen, dan biofilm. Banyak penelitian telah menunjukkan terdapatnya biofilm bakteri pada pasien dengan RSK. Biofilm bakteri dapat memfasilitasi terjadinya resistensi pada antibiotik. CT Scan sinus paranasal (SPN) merupakan pemeriksaan penunjang pilihan untuk diagnosis radiologik RSK. Lund dan Mackay telah mengembangkan suatu sistem berdasarkan skor dari CT Scan SPN untuk menilai kuantifikasi proses peradangan pada sinus paranasal. Beberapa penelitian menunjukkan bahwa pasien dengan biofilm bakteri memiliki skor Lund-Mackay CT Scan SPN yang lebih tinggi pada saat pra operatif. Tujuan: Penelitian ini bertujuan untuk mengetahui peran biofilm bakteri terhadap derajat keparahan RSK berdasarkan skor Lund-Mackay. Metode: Penelitian ini adalah penelitian cross-sectional dengan jumlah total sampel adalah 48 orang pasien RSK. Sekret hidung diambil menggunakan kapas lidi steril dengan swab pada meatus medius lalu dilakukan identifikasi bakteri dan pemeriksaan biofilm dengan tube method. Skor Lund-Mackay dihitung dari CT Scan SPN potongan koronal. Data dianalisis dengan uji Fisher. Hasil: Proporsi pasien RSK dengan skor Lund-Mackay yang tinggi lebih banyak pada pasien dengan biofilm (46,2%), dibandingkan tanpa biofilm (44,4%). Secara statistik tidak terdapat perbedaan bermakna pada skor Lund-Mackay antara pasien dengan biofilm dan tanpa biofilm (p=1,000). Kesimpulan: Tidak terdapat hubungan antara biofilm bakteri dengan derajat keparahan RSK berdasarkan skor Lund-Mackay. Kata Kunci: Rinosinusitis kronis, biofilm bakteri, tube method, skor Lund-Mackay ABSTRACT Background: Chronic rhinosinusitis (CRS) is inflammation of the nose and paranasal sinuses with the symptoms duration more than 12 weeks. Many conditions have been linked to its pathogenesis such as bacterial and fungal infection, superantigens and biofilm. Many studies showed the presence of bacterial biofilms in patients with CRS. Bacterial biofilms can facilitate the resistance to antibiotics. Paranasal sinuses (PNS) CT scan is the method of choice for radiological diagnosis of CRS. Lund and Mackay has developed a scoring system based on the CT finding to assess the quantification of inflammatory process in PNS. Some research suggested that patients with bacterial biofilms have higher Lund-Mackay score pre-operatively. Purpose: To determine the role of bacterial biofilms to the severity of CRS according to Lund-Mackay score. Methods: This was a cross-sectional study with 48 CRS patient’s sample. Nasal discharges were taken by swab in middle meatal using sterile cotton buds, followed by identification of bacteria and detection of bacterial biofilms using tube method. Lund-Mackay score was counted from coronal section of PNS CT Scan. Data was analyzed by Fisher’s exact test. Results: Proportion of patients CRS with high Lund-Mackay score was more common in patient with biofilm (46.2%) compared to patients without biofilm (44.4%). Statistically, there was no significant difference of Lund-Mackay score between patient with biofilm and without biofilm (p=1.00). Conclusion: There was no relationship between the bacterial biofilm with the severity of CRS according to Lund-Mackay score. Keywords: Chronic rhinosinusitis, bacterial biofilm, tube method, Lund-Mackay scores

Efek Larvasida Ekstrak Etanol Daun Sirih (Piper betle.L) terhadap Larva Aedes aegypti Esy Maryanti; John Rico Manalu; Yolazenia Yolazenia; Suri Dwi Lesmana; Mislindawati Mislindawati
Jurnal Ilmu Kedokteran Vol 16, No 1 (2022): Jurnal Ilmu Kedokteran
Publisher : Fakultas Kedokteran Universitas Riau

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.26891/JIK.v16i1.2022.36-40

Betel a leaf is a medicinal plant and consists of alkaloids, saponins and eugenol. Based on the experiment done to mosquito larvae by Cheng et al. resulted the extract of betel leaf has LD50 was 33 ppm. This research aimed to determine LC50 and LC90 of ethanolic extract of betel leaf (Piper betle L.) on the larvae of Aedes aegypti. The preliminary test had done to determine 10-90% mortality. Following concentrations that used for the final test were 300 ppm, 400 ppm, 600 ppm, 800 ppm, 1000 ppm, 1200 ppm, 1400 ppm, and one negative control. LC50 value from ethanolic extract of betel leaf was 467,441 ppm and LC90 value was 869,412 ppm. Larvicides effect from betel leaf because of chemical compound which had positive allosteric modulator of GABA mechanism. In conclusion, ethanolic extract of betel leaf (Piper betle L.) is potential to develop as mosquito larvicides.

Edukasi Menjaga Kesehatan Telinga dan Pemeriksaan Telinga pada Anak Panti Asuhan di Desa Rimbo Panjang, Kecamatan Tambang, Kabupaten Kampar Yolazenia Yolazenia; Asmawati Asmawati; Loriana Ulfa
Jurnal Kreativitas Pengabdian Kepada Masyarakat (PKM) Vol 5, No 4 (2022): Volume 5 No 4 April 2022
Publisher : Universitas Malahayati Lampung

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.33024/jkpm.v5i4.5418

ABSTRAK Kesehatan telinga yang tidak dijaga dengan baik, dapat menyebabkan gangguan pendengaran. Gangguan pendengaran pada anak dapat menyebabkan sulit berkomunikasi dan menerima pelajaran sehingga prestasi menurun. Kegiatan ini bertujuan memberikan pengetahuan mengenai menjaga kesehatan telinga dan melakukan pemeriksaan telinga. Kegiatan dilakukan di Panti Asuhan Baiturrahmah yang berlokasi di Desa Rimbo Panjang, Kecamatan Tambang, Kabupaten Kampar, Riau. Kegiatan diawali dengan memberikan penyuluhan mengenai menjaga kesehatan telinga dilanjutkan dengan pemeriksaan telinga. Kegiatan diikuti oleh 42 orang anak. Sebelum dan sesudah penyuluhan diberikan pre dan post test dengan hasil rata-rata 46,67 dan 70,48, terdapat peningkatan pengetahuan yang signifikan pada anak mengenai kesehatan telinga. Dari hasil pemeriksaan didapatkan 15 orang anak dengan serumen baik pada satu atau kedua telinga diantaranya 3 orang berupa serumen prop, dan 1 orang terdapat benda asing semut di liang telinga. Melalui kegiatan ini terdapat peningkatan pengetahuan dari anak-anak penghuni panti asuhan mengenai cara menjaga kesehatan telinga dan memiliki telinga yang lebih bersih dan sehat setelah dilakukan pemeriksaan. Kata kunci: panti asuhan, pendengaran, serumen, telinga ABSTRACT Ear health if not maintained properly, can cause hearing loss. Hearing loss in children can cause difficulties in communicating and receiving lessons so that achievement decrease. The aims of this activity was to provide knowledge about ear health and conduct ear examinations. The activity was carried out at the Baiturrahmah Orphanage located in Rimbo Panjang Village, Tambang District, Kampar Regency, Riau. The activity began with providing counseling on how to maintain ear health followed by ear examination. This activity was attended by 42 children living in the orphanage. Before and after being given education we provided pre and post test with the average result 46.67 and 70.48, there was a significant increase in children's knowledge about ear health. From the results of the examination, it was found that 15 children had cerumen in one or both ears, including 3 in the form of cerumen prop, and 1 person with a foreign body ants in the ear canal. Through this activity there was an increase in the knowledge of the children living in the orphanage about how to maintain healthy ears and have cleaner and healthier ears after the examination. Keywords: cerumen, ear, hearing, orphanage

Cutaneus Horn pada Aurikula Yolazenia Yolazenia; Harianto Harianto; Elva Rosiana
Jurnal Ilmu Kedokteran Vol 16, No 2 (2022): Jurnal Ilmu Kedokteran
Publisher : Fakultas Kedokteran Universitas Riau

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.26891/JIK.v16i2.2022.130-133

A cutaneous horn is a hard cone-shaped protrusion consisting of dense keratin resembling animal horns, which occurs due to abnormalities in the spinous layer of the epidermis, causing excess keratin accumulation. This disease can be found in any body part, especially in regions exposed to a lot of sunlight, such as the ears. Surgical excision is the treatment of choice for this disease. One case was reported in a male patient aged 75 years with a bulge on the left auricle. The patient underwent surgical excision as management and histopathological examination confirmed the diagnosis of the cutaneous horn with mild-moderate squamous epithelial cell dysplasia. Because of the high association with premalignant and malignant conditions, patients should be followed up regularly to prevent a recurrence.

Pemeriksaan dan Edukasi Gangguan Pendengaran Pada Anak Panti Asuhan Yolazenia Yolazenia; Asmawati Asmawati; Harianto Harianto
Berdikari: Jurnal Inovasi dan Penerapan Ipteks Vol 11, No 1 (2023): February
Publisher : Universitas Muhammadiyah Yogyakarta

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.18196/berdikari.v11i1.16639

Unhealthy ears may cause hearing loss. This issue may affect children to have difficulty communicating with others and decrease learning achievement at school. This community service activity aimed to give knowledge about hearing loss and conduct hearing examinations in orphanage children. This community service was held at the Aulia Al-Ikhlas Orphanage in Sungai Pagar Village, Kampar Kiri Hilir District, Kampar Regency, Riau. At the beginning of the activity, we provided counseling about hearing loss, followed by ear and hearing examinations using a tuning fork. Before and after the counseling, respondents filled out a questionnaire to assess knowledge about hearing loss. Twenty-four residents of the orphanage attended this activity. The questionnaires found that children's knowledge about hearing loss and ear health increased significantly after the counseling. The examination results found cerumen in 14 children, 4 with conductive hearing loss and 2 with sensory neural hearing loss. As a result, this community service activity can increase the knowledge of orphanage children about hearing loss and make their ears cleaner and healthier.

Gambaran Penggunaan Insektisida Rumah Tangga di Kelurahan Tangkerang Barat Kecamatan Marpoyan Damai, Pekanbaru Elva Susanty; Yolazenia Yolazenia; Dedi Afandi; Suri Dwi Lesmana; Mislindawati Mislindawati; M.Farhan Akhyar; M.Randy Kurniadi; M.Teguh Hutomo
Jurnal Ilmu Kedokteran Vol 17, No 2 (2023): Jurnal Ilmu Kedokteran
Publisher : Fakultas Kedokteran Universitas Riau

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.26891/JIK.v17i2.2023.121-126

Dengue Hemorrhagic Fever (DHF) is a potentially fatal disease that threatening global health, including Indonesia. Various efforts have been made to control DHF, one of them is by means of vector control. Household based insecticides are widely used by the community in controlling insect vectors, including Ae.aegypti as the main vector of DHF. This study aimed to describe the use of household insecticides in the Tangkerang Barat Sub District, Marpoyan Damai District. This study was conducted in September-November 2022 with a total of 100 respondents. The sample selection technique used was simple random sampling from 4 RWs. Data collection was carried out using guided interviews with 4 questions to respondents who used insecticides. Data analysis was carried out using univariate analysis. This study showed that almost all respondents (98%) used household insecticides, the most widely used type of formulation was aerosol (51%), active ingredient was dimeflutrin 0.02%; cypermethrin 0.10% (25.5%), used once a day (75.5%) and used at night (98%). Improper use of household insecticides can have negative effects on the environment, humans, and the occurrence of resistance. Mosquito Nest Eradication needs to be further improved in controlling Ae.aegypti.

Co-Authors Afrinaldi Aldi Asmawati Asmawati Asmawati Asmawati Aziz Djamal Bestari Jaka Budiman Dedi Afandi Dolly Irfandy Effy Huriyati Elva Rosiana Elva Susanty Esy Maryanti Fadly Mulia Febri Romaito Romaito Harianto Harianto Harianto Harianto Harianto Harianto Inayah Inayah Iqbal Teguh Riady John Rico Manalu Loriana Ulfa M.Farhan Akhyar M.Randy Kurniadi M.Teguh Hutomo Mislindawati Linda Mislindawati Mislindawati Novisa Dwi Utami Retni Tri Handayani Rizanda Machmud Suri Dwi Lesmana

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