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All Journal Jurnal Ilmu Kedokteran (Journal of Medical Science) Jurnal Kedokteran Syiah Kuala Jurnal Kedokteran Brawijaya Majalah Kedokteran Bandung Jurnal Online Mahasiswa (JOM) Bidang Kedokteran Jurnal Kesehatan Andalas Biomedika Chimica et Natura Acta Abdimas Talenta : Jurnal Pengabdian Kepada Masyarakat Indonesian Journal of Obstetrics & Gynecology Science Acta Biochimica Indonesiana Bioscientia Medicina : Journal of Biomedicine and Translational Research Indian Journal of Forensic Medicine & Toxicology Narra J Bioscientia Medicina : Journal of Biomedicine and Translational Research
Maya Savira
Mikrobiologi Fakultas Kedokteran Universitas Riau Pekanbaru
Agriculture, Biological Sciences & Forestry Biochemistry, Genetics & Molecular Biology Chemistry Dentistry Environmental Science Health Professions Immunology & microbiology Law, Crime, Criminology & Criminal Justice Materials Science & Nanotechnology Medicine & Pharmacology Neuroscience Public Health Social Sciences

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GAMBARAN PENGETAHUAN IBU TERHADAP DIARE AKUT BALITA DI RSUD ARIFIN ACHMAD PROVINSI RIAU DAN PUSKESMAS RAWAT INAP PEKANBARU Dwiriyanti H, Dhita Natasha; Savira, Maya; ", Suyanto
Jurnal Online Mahasiswa (JOM) Bidang Kedokteran Vol 2, No 1 (2015): Wisuda Februari 2015
Publisher : Jurnal Online Mahasiswa (JOM) Bidang Kedokteran

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Abstract

ABSTRACTDiarrhea is the most cases that has increased morbidity and mortality, especially children under five year. Diarrhe was the second largest after pneumonia disease. Diarrhea disease in Indonesia is a major cause of infant mortality is approximately 31.4% and 25.2% in children under five years. Riau is a province that has a prevalence rate of diarrhea above the national average. There are several causes of diarrhea and for developing countries such as Indonesia the majority caused by infection. Infection can be derived from environmental factors, especially the children and mothers who are less hygienic. Diarrhea in children require extra attention because more than 70 % of the body of water and likely to fall to dehydration of the weight and the role of mother to know and take care of diarrhoea in the house is very necessary. This study will show reveal the mother's knowledge towards acute diarrhea in toddler. This research was a descriptive prospective with cross-sectional approach. This study used interviews and questionnaire instruments about knowledge of the mother. These samples included 105 respondents from Riau Province Arifin Achmad Hospital and Health Center Inpatient Pekanbaru. The results showed that both the mother's knowledge as much as 67 mothers (63.8%), quite as much as 24 mothers (22.9%) and who have less knowledge as much as 14 mothers (13.3%).Keywords: Diarrhea, morbidity, mortality, knowledge, cross-sectional
PROFIL PENDERITA TUBERKULOSIS PARU YANG DI RAWAT INAP DI BAGIAN PARU RUMAH SAKIT UMUM DAERAH ARIFIN ACHMAD PROVINSI RIAU PERIODE 01 JANUARI - 31 DESEMBER 2013 Mallinda, Erfina; Af, Zarfiardy; Savira, Maya
Jurnal Online Mahasiswa (JOM) Bidang Kedokteran Vol 3, No 1 (2016): Wisuda Februari 2016
Publisher : Jurnal Online Mahasiswa (JOM) Bidang Kedokteran

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ABSTRACT Mycobacterium tuberculosis has been infecting one-third of world population, World Health Organization (WHO) report about 8 milion of world population suffered from tuberculosis with 3 milion people death in a year. The disease is pertained cruetly, but the awareness of sosiety is still low. It can be seen from the finding number of lungs tuberculosis patient. This study intended to look at the profile of lung tuberculosis patients who were stayed at department of respiratory medicine Arifinn Achmad general hospital Riau Province period of 01 january – 31 december 2013. The research used descriptive method which is done by retrospective approach. The result of this study shown that most of lung tuberculosis patient were male 35 people (70%), with range of age 55-64 years old. The average patient was not working around 30 people (60%). The mayority of the patient had BTA (acid-fast bacillus) positive result of their sputum test 44 people (88%). Most of the patient have comorbidities around 26 people (52%), and 10 people (20%) had suspected of MDR TB.Keywords: profile, lung tuberculosis, research
Prevalensi dan Pola Sensitivitas Enterobacteriaceae Penghasil ESBL di RSUD Arifin Achmad Pekanbaru Anggraini, Dewi; Sholihin, Uswathun Hasanah; Savira, Maya; Djojosugito, Fauzia Andrini; Irawan, Dino; Rustam, Ruza Prima
Jurnal Kedokteran Brawijaya Vol 30, No. 1 (2018)
Publisher : Fakultas Kedokteran Universitas Brawijaya

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.21776/ub.jkb.2018.030.01.9

Abstract

Resistensi antibiotik merupakan masalah besar baik di rumah sakit maupun di masyarakat, resistensi menyebabkan pilihan terapi infeksi menjadi terbatas. Prevalensi resistensi antibiotik cenderung makin meningkat, salah satu diantaranya adalah bakteri ESBL (extended spectrum beta lactamases), suatu kelompok bakteri penghasil enzim yang dapat menghidrolisis antibiotik beta laktam yang mengandung grup oxyimino seperti sefalosporin generasi satu sampai ketiga dan aztreonam. Penelitian ini  dilakukan secara deskriptif retrospektif yang bertujuan untuk mengetahui prevalensi ESBL pada Klebsiella pneumoniae dan Escherichia coli, serta pola sensitivitasnya di RSUD Arifin Achmad Pekanbaru. Data diambil dari hasil kultur bakteri dan uji resistensi antibiotik dari berbagai spesimen klinik yang diperiksa di Laboratorium Mikrobiologi RSUD Arifin Achmad selama tahun 2015. Uji ESBL dilakukan dengan alat VITEK 2 compact yang membandingkan antara proporsi penurunan pertumbuhan bakteri terhadap antibiotik sefalosporin saja dengan antibiotik kombinasi sefalosporin ditambah asam klavulanat. Hasil penelitian menunjukkan ESBL-K. pneumoniae sebesar 66,2%, dan ESBL-E. coli 62,2%, dan total rata-rata pada kedua bakteri 65,2%. Prevalensi ESBL-K. pneumoniae dan ESBL-E. coli paling tinggi berasal dari ruangan Instalasi Perawatan Intensif Anak dan berasal dari spesimen sputum dan pus, namun secara statistik tidak didapatkan perbedaan bermakna proporsi ESBL positif dan negatif berdasarkan asal ruangan dan jenis spesimen. Sensitivitas ESBL-K. pneumoniae dan ESBL-E. coli paling baik dengan antibiotik golongan karbapenem, amikasin dan tigesiklin. Penelitian ini menunjukkan tingginya prevalensi K. pneumoniae dan E. coli penghasil ESBL di RSUD Arifin Achmad dibanding beberapa rumah sakit rujukan nasional dii Indonesia. Saran untuk menurunkan angka ESBL dengan cara mencegah transmisi melalui penerapan kewaspadaan kontak dan kewaspadaan berbasis transmisi, aspek pencegahan dan pengendalian infeksi dan peningkatkan rasionalisasi penggunaan antimikroba harus dilakukan.
Prevalensi dan Pola Sensitivitas Antimikroba Multidrug Resistant Pseudomonas aeruginosa di RSUD Arifin Achmad Anggraini, Dewi; Gusti Yulindra, Utari; Savira, Maya; Djojosugito, Fauzia Andrini; Hidayat, Nopian
Majalah Kedokteran Bandung Vol 50, No 1 (2018)
Publisher : Faculty of Medicine, Universitas Padjadjaran

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (427.057 KB) | DOI: 10.15395/mkb.v50n1.1150

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Resistensi antimikrob merupakan salah satu masalah kesehatan masyarakat yang besar yang dihadapi manusia sejak era ditemukan antimikrob. Angka multidrug resistant P. aeruginosa salah satunya semakin meningkat di berbagai belahan dunia yang berdampak pada kesulitan penanganan infeksi oleh bakteri ini. Penelitian deskriptif retrospektif ini bertujuan mengetahui prevalensi MDR P.aeruginosa dan pola sensitivitasnya. Data diambil dari hasil kultur bakteri dan uji resistensi antibiotik dari berbagai spesimen klinis pasien di RSUD Arifin Achmad sepanjang tahun 2015. Uji resistensi dilakukan dengan menggunakan alat Vitek 2 compact. MDR P. aeruginosa didefinisikan sebagai P. aeruginosa yang tidak sensitif terhadap tiga atau lebih golongan antibiotik berikut: meropenem atau imipenem, siprofloksasin, gentamisin atau amikasin, seftazidim atau sefepim, dan piperasilin/tazobaktam. Prevalensi MDR P. aeruginosa adalah 45,5%. Isolat MDR P. aeruginosa serta paling banyak berasal dari instalasi perawatan surgikal dan instalasi perawatan intensif, dan paling banyak berasal dari spesimen pus dan sputum. Sensitivitas P. aeruginosa paling baik dengan amikasin (76,9%), piperasilin/tazobaktam (57,2%), meropenem (57,0%), gentamisin (54,5%), sefepim (53,7%), seftazidim (49,6%), ciprofloksasin (48,8%) dan aztreonam (35,5%). Sensitivitas MDR P.aeruginosa terhadap antibiotik jauh lebih rendah dibanding dengan P. aeruginosa. Penelitian ini menunjukkan angka MDR P. aeruginosa tinggi khususnya di Pekanbaru. Pola sensitifas P. aeruginosa dapat menjadi pedoman dalam memilih antibiotik yang sesuai untuk infeksi karena P. aeruginosa.Kata kunci: Multidrug resistant, Pekanbaru, pseudomonas aeruginosa, sensitivitas antibiotik Prevalence and Antimicrobial Susceptibility Profile of Multidrug Resistant Pseudomonas aeruginosa in Arifin Achmad General HospitalAntimicrobial resistance is one of major public health problems since the era of antimicrobial discovery, inclusing multidrug resistant (MDR) P. aeruginosa. The prevalence of this resistance  is increasing in different parts of the world, leading to the difficulties in dealing with this bacteria. The aim of this descriptive retrospective study was to determine the prevalence of MDR P. aeruginosa and its susceptibility profile. Data were collected from the bacteria cultures and antibiotic susceptibility test results from various clinical specimens in Arifin Achmad General Hospital throughout 2015. The test was performed in VITEK 2 Compact. MDR P. aeruginosa is defined as P. aeruginosa which is not sensitive to three or more following antibiotics: meropenem or imipenem, ciprofloxacin, gentamicin or amikacin, ceftazidime or cefepime, and piperacilin/tazobactam. The prevalence of MDR P. aeruginosa was 45.5%. The isolates of MDR P. aeruginosa was mostly derived from pus and sputum specimens from the surgical ward and intensive care unit. .  The most sensitive antibiotics was amikacin (76.9%) followed by piperacilin/tazobactam (57.2%), meropenem (57.0%), gentamicin (54.5%), cefepime (53.7%), ceftazidime (49.6%), ciprofloxacin (48.8%), and aztreonam (35.5%). Antibiotic sensitivity in MDR P. aeruginosa was much lower than in P. aeruginosa. This study shows a high prevalence of MDR P. aeruginosa, especially in Pekanbaru. This susceptibility profile can serve as a guideline for the selection of appropriate antibiotics for infections caused by P. aeruginosa.Key words: Antibiotic susceptibility, multidrug resistant, Pekanbaru, pseudomonas aeruginosa
PENCEGAHAN DAN PENATALAKSANAAN INFEKSI HIV/AIDS PADA KEHAMILAN Suhaimi, Donel; Savira, Maya; Krisnadi, Sofie R.
Majalah Kedokteran Bandung Vol 41, No 2
Publisher : Faculty of Medicine, Universitas Padjadjaran

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Abstract

Acquired immunodeficiency syndrome (AIDS) adalah penyakit yang disebabkan oleh infeksi virus human immunodeficiency virus (HIV). AIDS dikarakteristikkan sebagai penyakit imunosupresif berat yang sering dikaitkan dengan infeksi oportunistik dan tumor ganas serta degenerasi susunan saraf pusat. Penyebaran HIV ini berkembang dengan cepat dan mengenai wanita dan anak-anak. AIDS menyebabkan kematian lebih dari 20 juta orang setahun. Tahun 2003 diperkirakan 700.000 bayi baru lahir terinfeksi HIV di seluruh dunia. Angka morbiditas dan mortalitas yang disebabkan oleh HIV semakin meningkat dan merupakan masalah kesehatan masyarakat yang paling penting di semua negara. Penggunaan obat antivirus seperti highly active antiretroviral therapy (HAART) dan persalinan berencana dengan seksio sesaria telah menurunkan angka transmisi perinatal mother to child trasmission (MTCT) penyakit ini dari 30% menjadi 20%. Manejemen antenatal, persalinan, dan perawatan pascasalin yang terkontrol dengan baik pada ibu hamil dengan HIV dapat mencegah transmisi perinatal.Kata kunci : AIDS, HAART, MTCTPREVENTION AND MANAGEMENT OF HIV INFECTION (AIDS) IN PREGNANCYAcquired immunodeficiency syndrome (AIDS) is a disease which caused by human immunodeficiency virus (HIV). Characteristic of AIDS is due to severe immunosupresive disease which related to opportunistic infection, malignant tumour and central nervous system degeneration. HIV spread widely and mostly infect women and children. Mortality rate of AIDS are more than 20 million people per year. In 2003, 700,000 newborn were infected by HIV in the world. Morbidity and mortality rate of HIV are highly increase dan become an important public health problem in all around the world. Using of antiviral drugs like highly active antiretroviral therapy (HAART) and ceasarean labor has decreased the perinatal transmission (mother-to-child trasmission=MTCT) rate of this disease from 30% to 20%. The intensive control in management of antenatal care, labor and delivery for the pregnant women with HIV can prevent the perinatal transmission.Key words: AIDS, HAART, MTCT DOI: http://dx.doi.org/10.15395/mkb.v41n2.184
Amniotic Band Syndromewith Unique Clinical Presentations: A Case Report Donel Suhaimi; Maya Savira; ShintaPuja Tilusari
Indian Journal of Forensic Medicine & Toxicology Vol. 15 No. 4 (2021): Indian Journal of Forensic Medicine & Toxicology
Publisher : Institute of Medico-legal Publications Pvt Ltd

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.37506/ijfmt.v15i4.16839

Abstract

Amniotic band syndromeis a rare congenital disorder which associated with physical abnormalities suchas disruption, deformation, and malformations of organs. The most common abnormalities usually involvethe limbs that could range from simple constriction rings to complete amputation.In this case report, wereport anamniotic band syndrome with unique clinical presentations. The case was a new born male babywho was normally delivered and presented with a ring-like constriction at over middle right lower limband fusion (syndactyly) of left lower limb and right arm. In this report we also discuss different diagnosticmodalities which could be used in diagnosingamniotic band syndrome, the risk factors, type of amnioticband syndrome, post-natal diagnose, as well as the therapy.
Imunologi Human Immunodeficiency Virus (HIV) dalam Kehamilan Maya Savira
Jurnal Ilmu Kedokteran Vol 8, No 1 (2014): Jurnal Ilmu Kedokteran
Publisher : Fakultas Kedokteran Universitas Riau

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (33.085 KB) | DOI: 10.26891/JIK.v8i1.2014.1-7

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Human Immunodeficiency Virus can be spread through sexual contact , blood products and vertical transmission ofthe mother to the fetus . The high incidence of HIV / AIDS around the world in women over 15 years old and childrenunder the age of 15 years gives an overview of HIV / AIDS cases in pregnant women likely to have a high incidence.HIV viral RNA viruses belonged to two different types , namely HIV - 1 and HIV - 2 . Most cases are caused by HIV- 1. HIV primarily infects CD4 lymphocytes or T helper ( Th ), the numbers will decrease , as well as the function ofthe immune system will decrease. During pregnancy occurs emphasis on immune cells, with or without HIV infection.Study in France showed no significant progression between the immune system of pregnant women with HIV andnormal pregnant women . T reg on HIV infection in lymphoid tissue accumulated and the number of T reg postpartum was higher in patients with HIV infection compared to HIV- negative . Human Leukocyte antigen - G ( HLA- G ) inhibits cell-mediated immune response and can penetrate the placenta spread of HIV - 1 infection and increasethe risk of vertical transmission . Major histocompatibility complex ( MHC ) encodes HLA - G to inhibit natural killercells ( NK cells) that supports the entry of the virus passes through the placental barrier in HIV- 1 positive pregnantwomen . HIV infection activates CD8 expressing HLA - DR antigen . CD8 immune activation in chronic HIV becomesa factor decreasing CD4 count . The expression of HLA - DR and CD38 on CD8 T lymphocytes that recognize CD4eliminated by HIV infection Total CD8 , CD38 , and HLA - DR is reduced in HIV- positive pregnant women may bea prognostic parameters of immune status.
Biologi Molekuler Human Papilloma Virus Maya Savira
Jurnal Ilmu Kedokteran Vol 11, No 1 (2017): Jurnal Ilmu Kedokteran
Publisher : Fakultas Kedokteran Universitas Riau

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (232.866 KB) | DOI: 10.26891/JIK.v11i1.2017.1-6

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Persistent infection of the high-risk group Human Papilloma Virus (hrHPV) has been known to cause cervical cancer. Currently cervical cancer still ranks as the number two of most malignant disease in women. The infection of HPV that lead to cancer cells to form can be known through the structure of the HPV virus itself and what particles in the virus play a role in initiating the carcinogenic process of its host cell.
Luaran Kehamilan Dengan Sistemik Lupus Eritematosus Maya Savira
Jurnal Ilmu Kedokteran Vol 5, No 2 (2011): Jurnal Ilmu Kedokteran
Publisher : Fakultas Kedokteran Universitas Riau

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (37.993 KB) | DOI: 10.26891/JIK.v5i2.2011.63-70

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Systemic lupus erythematosus often abbreviated to SLE or lupus, is a systemicautoimmune disease (or autoimmuneconnective tissue disease) that can affect any part ofthe body. As occurs in other autoimmune diseases, the immunesystem attacks the body’scells and tissue, resulting in inflammation and tissue damage. It is a type IIIhypersensitivityreaction caused by antibody-immune complex formation. Women with lupus are at risk for various complications ofpregnancy, and those with antiphospholipid antibodies may have an increased risk of miscarriage. Systemic lupuserythematosus increases the risk of spontaneous abortion, intrauterine fetal death, preeclampsia, intrauterine growthretardation, and preterm birth. The outcome for both mother and child is best when systemic lupus erythematosus hasbeen under good control for at least six months before pregnancy and when the kidney disease is in remission.
Validitas Metode Konvensional Modifikasi Terhadap Metode Konvensional Dan ChromidTM Esbl Untuk Deteksi Bakteri-bakteri Penghasil Extended-spectrum Beta-lactamases Maya Savira
Jurnal Ilmu Kedokteran Vol 8, No 2 (2014): Jurnal Ilmu Kedokteran
Publisher : Fakultas Kedokteran Universitas Riau

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (67.502 KB) | DOI: 10.26891/JIK.v8i2.2014.81-90

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Extended spectrum beta lactamases (ESBL) enzymes producing microorganisms are a major problem in increasingof betalactamases antibiotics resistance include cephalosporins. These enzymes are produced by gram negativesbacilli especially a variety of Enterobacteriaceae, however the most common ESBL producing microorganisms areKlebsiella spp and Escherichia coli. Detection and identification of gram negatives bacilli producing ESBL arechallenging for clinical microbiology laboratory to determine the best method to get the optimal results. The objectiveof this study was to determine the sensitivity and specificity of conventional method modification using MacConkeyadded with cefpodoxim disc 10 μg, 2 mg/l to conventional method and ChromIDTM ESBL. The method of this studywas an observasional analytical study using cross sectional design on 200 isolates, which were Escherichia coli,Klebsiella spp, Salmonella typhi, Proteus mirabilis, Pseudomonas aeruginosa, Serratia spp, and Enterobacter spp.The sensitivity of conventional method modification was 93,8%, conventional method was 68,8% and ChromIDTMESBL method was 100%. The spesificity of conventional method modification was 98,7%, conventional method was11,2% and ChromIDTM ESBL method was 100%. The sensitivity of conventional method modification was higherthan conventional method and as good as ChromIDTM ESBL for detecting ESBL producing bacterias.
Co-Authors Admiral, Muhammad Z. Afief, Arief R. Ahmad Fahruddin Amalia, Aisyah Sabrina Amelia, Putri Amru Sofian Boby Franswinsly Ritonga Citra Ayu Anggreli Darmawi Darmawi Dewi Anggraini Dhini Aiyulie Novri Dhita Natasha Dwiriyanti H Dino Irawan Donel S Donel S Enikarmila Asni Erfina Mallinda, Erfina Farah Mardhiyah Farniga, Arnaldi Fauzia Andrini Gusti Yulindra, Utari Hidayat, Nopian Ika A. Rini, Ika A. Ilmiah, Zidny Inayah Inayah Inglin, Mark Irham, Lalu M. Kemal, Rahmat A. Lubis, Nenni Dwi Aprianti M. Yulis Hamidy Machyuddin T.M Pangaribuan Mahargyarani, Azza E. Maryanti, Yossi Muhammad Ihsan Nurfi Pratiwi, Nurfi Putra, Andani E. Rachmadina, Rachmadina Rahmat Azhari Kemal Rangkuti, Ina F. Ratu Astuti Dwi Putri Razali, Renardy R. Resty Yuwandari rusdiana Ruza Prima Rustam Ruza Prima Rustam, Ruza Prima S, Donel Sabella Gustika Vernanda ShintaPuja Tilusari Sholihin, Uswathun Hasanah Sofie R. Krisnadi Suyanto " Tobing, Tina CL. Ulfah, Aida J. Vani Ardiani Viandy , Vincent Wardana, Rexi Dwi Widjaja, Sry Suryani Wirawan Adikusuma Yosephine, Astrid G. Yossi Maryanti Yuana Nurulita Yuwandari, Resty Zarfiardy Af, Zarfiardy Zulmaeta