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All Journal MAHESA : Malahayati Health Student Journal KOLONI
Paskalis Andrew Gunawan
Universitas Tarumanagara
Civil Engineering, Building, Construction & Architecture Dentistry Health Professions Law, Crime, Criminology & Criminal Justice Nursing Public Health Social Sciences Other

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Correlation between Muscle Strength, Calf Circumference, Vitamin D, and IGF-1 on Depression in the Elderly Paskalis Andrew Gunawan; Anastasia Ratnawati Biromo; Alexander Halim Santoso; Bryan Anna Wijaya; Kasvana Kasvana; Louise Audrey Sukianto; Yohanes Firmansyah
MAHESA : Malahayati Health Student Journal Vol 6, No 5 (2026): Volume 6 Nomor 5 (2026)
Publisher : Universitas Malahayati

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.33024/mahesa.v6i5.22435

Abstract

ABSTRACT Depression in the elderly is a multifaceted issue influenced by various physiological factors. This study investigates the correlation between muscle strength, calf circumference, Vitamin D, and Insulin-like Growth Factor 1 (IGF-1) levels and their collective impact on depression among the elderly.  This study aims to understand the correlation between muscle strength, calf circumference, Vitamin D, and IGF-1 levels on depression to develop targeted interventions to improve mental health outcomes in this demographic. This cross-sectional study involved 82 older people at RPTRA Krendang. Depression is measured using the Geriatric Depression Scale (GDS). Data were analyzed using Spearman's Rho to see the Correlation between Muscle Strength, Calf Circumference, Vitamin D, and IGF-1 on Depression in the Elderly. The study found most respondents were female (78%), with an average age of 74.34 years, and according to the Geriatric Depression Scale, the majority (59.8%) of respondents were normal. This study highlighted significant correlations between muscle strength, calf circumference, and decreased Vitamin D and IGF-1 levels with higher depression scores. These findings suggest that diminished physical health markers and nutrient deficiencies are associated with increased depressive symptoms in the elderly. Measuring muscle strength, calf circumference, Vitamin D, and IGF-1 levels is a good approach to understanding depression in the elderly that will lead to effective interventions by health workers and improve quality of life. Keywords: Calf Circumference; Depression; IGF-1; Muscle Strength; Vitamin D. 
Hepatitis Iskemik Akibat Syok Hipovolemik dengan Trombositopenia dan Disfungsi Renal: Sebuah Laporan Kasus Muhammad Agus Putra; Syaifun Niam; Paskalis Andrew Gunawan
KOLONI Vol. 5 No. 3 (2026): SEPTEMBER 2026
Publisher : Universitas Pahlawan Tuanku Tambusai

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.31004/koloni.v5i3.1068

Abstract

Hypovolemic shock is a condition that may lead to systemic hypoperfusion and subsequently result in multiorgan dysfunction. This case report describes a 32-year-old man who presented to the emergency department with recurrent vomiting approximately 30 times within one day, accompanied by generalized weakness, dyspnea, and abdominal pain. Physical examination revealed severe hypotension (73/44 mmHg), tachycardia, and signs of dehydration, supporting the diagnosis of hypovolemic shock. Laboratory investigations demonstrated hemoconcentration, severe thrombocytopenia (15 ×10³/µL), elevated serum creatinine and urea levels, hyperbilirubinemia, and markedly increased aminotransferase levels (AST 1088 U/L; ALT 852 U/L). Abdominal ultrasonography revealed grade 1 hepatic steatosis, cholecystitis with cholelithiasis, bilateral chronic kidney disease, and a right renal cyst. The patient received fluid resuscitation and supportive therapy, resulting in clinical and hemodynamic improvement. Serial laboratory evaluations showed an increase in platelet count to 118 ×10³/µL and a decline in AST and ALT levels to 222 U/L and 607 U/L, respectively, by the sixth day of hospitalization. This case highlights the importance of comprehensive evaluation in hypovolemic shock, as systemic hypoperfusion may lead to simultaneous dysfunction of multiple organ systems.
Co-Authors Alexander Halim Santoso Anastasia Ratnawati Biromo Bryan Anna Wijaya Kasvana Kasvana Louise Audrey Sukianto Muhammad Agus Putra Syaifun Niam Yohanes Firmansyah