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Peran Kopeptin Serum pada Anak dengan Pneumonia -, Carolina; Dalimunthe, Wisman
Cermin Dunia Kedokteran Vol 46, No 8 (2019): Kesehatan Anak
Publisher : PT. Kalbe Farma Tbk.

Pneumonia masih merupakan masalah kesehatan utama pada anak. Kopeptin merupakan rantai glikopeptida-asam amino dari prekursor hormon vasopresin arginin (AVP) yang juga dikenal sebagai hormon anti diuretik (ADH). Pada anak dengan pneumonia, dijumpai peningkatan kadar kopeptin serum yang berhubungan dengan tingkat keparahan pneumonia dan komplikasinya. Penelitian lanjutan terkait peran kopeptin sebagai uji diagnostik dan prediktor prognostik pneumonia pada anak masih dibutuhkan.Pneumonia remains as the major cause of health problem in children. Copeptin is an amino acids-glycopeptides precursor of arginine vasopressin (AVP), also known as anti-diuretic hormone. Children with pneumonia have increased level of serum copeptin which correlates with the severity and complications of pneumonia. Further investigations regarding the role of copeptin as diagnostic test and predictor of prognostic in childhood pneumonia are warranted.Â

Factors Influencing Tuberculosis Infection in Children with Close Contact of Adult Pulmonary Tuberculosis Patients Mayasri, Fadhliani; Dalimunthe, Wisman; Sianturi, Pertin; Amelia, Rina; Daulay, Rini Savitri; Meirina, Fathia
Jurnal Keperawatan Priority Vol. 8 No. 2 (2025)
Publisher : Universitas Prima Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.34012/jukep.v8i2.6647

This research aims to determine the factors that influence tuberculosis infection in children with close contact with adult pulmonary tuberculosis sufferers. This research is an analytical observational study with a consecutive sampling method at the Glugur Darat Health Center in November 2024 until January 2025. Bivariate analysis using chi-square to determine whether there is a relationship between the independent and dependent variables. The type of test used is the Fisher Exact and Kruskal Wallis Test. There is no multivariate test because there are no significant variables in the bivariate test. In total, in 42 samples there were 10 children with positive Mantoux tests. Of the 23 female children there were 7 (30.4%) with positive results and of the 19 male children there were 3 (15.8%) positive results. Of the 39 children with a history of BCG immunization, there were 10 (25.6%) with tuberculosis infection. Of the 37 children with parents whose income was <UMR, 10 children (27%) had tuberculosis infection. 37 children whose parents had junior high school education, 9 people (24.3%) had tuberculosis infection. 10 children aged 1-5 years and 6-10 years, there were 2 (20%) each with tuberculosis infection. 26 children aged 11-18 years, there were 6 people (27.3%) with tuberculosis infection. There was no significant relationship between age, gender, immunization status, nutritional status, parental income and parental education level in this research.

Factors Influencing Tuberculosis Infection in Children with Close Contact of Adult Pulmonary Tuberculosis Patients Mayasri, Fadhliani Putri; Dalimunthe, Wisman; Sianturi, Pertin; Amelia, Rina; Daulay, Rini Savitri; Meirina, Fathia
Jurnal Keperawatan Priority Vol. 8 No. 2 (2025)
Publisher : Universitas Prima Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.34012/jukep.v8i2.6647

This research aims to determine the factors that influence tuberculosis infection in children with close contact with adult pulmonary tuberculosis sufferers. This research is an analytical observational study with a consecutive sampling method at the Glugur Darat Health Center in November 2024 until January 2025. Bivariate analysis using chi-square to determine whether there is a relationship between the independent and dependent variables. The type of test used is the Fisher Exact and Kruskal Wallis Test. There is no multivariate test because there are no significant variables in the bivariate test. In total, in 42 samples there were 10 children with positive Mantoux tests. Of the 23 female children there were 7 (30.4%) with positive results and of the 19 male children there were 3 (15.8%) positive results. Of the 39 children with a history of BCG immunization, there were 10 (25.6%) with tuberculosis infection. Of the 37 children with parents whose income was <UMR, 10 children (27%) had tuberculosis infection. 37 children whose parents had junior high school education, 9 people (24.3%) had tuberculosis infection. 10 children aged 1-5 years and 6-10 years, there were 2 (20%) each with tuberculosis infection. 26 children aged 11-18 years, there were 6 people (27.3%) with tuberculosis infection. There was no significant relationship between age, gender, immunization status, nutritional status, parental income and parental education level in this research.

The Impact of Age on Seizure Severity Characteristics in Children With Drug Resistant Epilepsy Lestari, Tria Diana; Tanjung, Ika Citra Dewi; Lubis, Syamsidah; Harahap, Juliandi; Saing, Johannes Harlan; Dalimunthe, Wisman
Indonesian Journal of Global Health Research Vol 7 No 3 (2025): Indonesian Journal of Global Health Research
Publisher : GLOBAL HEALTH SCIENCE GROUP

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.37287/ijghr.v7i3.5890

Drug-resistant epilepsy (DRE) is found in up to one-third of individuals with epilepsy who have received appropriate therapy and this condition causes significant child morbidity and mortality. Epilepsy that appears at an early age is at higher risk of developing DRE. Objective to assess the effect of age on the characteristics of seizure severity in children with DRE. This study used a cross-sectional design involving 36 DRE patients aged 2-18 years at the Child Neurology Polyclinic, Adam Malik Hospital Medan, from September to October 2024. Seizure severity characteristics were assessed using the Global Assessment of the Severity of Epilepsy (GASE) questionnaire instrument. The categorical data are presented in the form of proportions and the effect of age on seizure severity characteristics was analyzed using the chi-square test. There were 36 children with DRE in this study, predominantly aged ≥ 10 years. Bivariate analysis showed a significant effect of age in children with drug resistant epilepsy only on the disruption of activity experienced by children with a p value = 0.036 (p <0.05). Most patients aged ≥ 10 years did not experience activity disorders or experienced mild activity disorders (73.9%), while in patients aged <10 years, most patients experienced severe activity disorders (61.5%). The age of children with drug resistant epilepsy have a significant effect on daily activity disorders.

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