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All Journal Paediatrica Indonesiana Majalah Kedokteran Nusantara The Journal Of Medical School Jurnal Respirasi (JR) Jurnal Keperawatan Priority Indonesian Journal of Global Health research Asian Australasian Neuro and Health Science Journal (AANHS-J) Journal of Endocrinology, Tropical Medicine, and Infectious Disease (JETROMI) Jurnal Al Ulum: LPPM Universitas Al Washliyah Medan

Rini Savitri Daulay, Rini Savitri

Department Of Child Health, University Of Sumatera Utara Medical School/H. Adam Malik Hospital, Medan, North Sumatera.

Author-ID : 3451844

Agriculture, Biological Sciences & Forestry Biochemistry, Genetics & Molecular Biology Chemical Engineering, Chemistry & Bioengineering Dentistry Economics, Econometrics & Finance Education Health Professions Immunology & microbiology Industrial & Manufacturing Engineering Languange, Linguistic, Communication & Media Mechanical Engineering Medicine & Pharmacology Neuroscience Nursing Public Health

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Mantoux test results and BCG vaccination status in TB-exposed children Fadilah Harahap; Ridwan M. Daulay; Muhammad Ali; Wisman Dalimunthe; Rini Savitri Daulay
Paediatrica Indonesiana Vol 55 No 1 (2015): January 2015
Publisher : Indonesian Pediatric Society

Background Tuberculosis (TB) infection is highly prevalent in Indonesia. The source of transmission of TB to a child is usually via an adult with sputum smear-positive pulmonary tuberculosis. The Mantoux test is a diagnostic tool for tuberculosis infection. The BCG vaccine has been used for the prevention of TB, but its efficacy is still debated. Objective To assess for an association between Mantoux test results and BCG vaccination in children who had contact with adult pulmonary tuberculosis and to assess for differences in Mantoux test induration with regards to nutritional status, age, type of TB contact, and time duration since BCG vaccination in BCG-vaccinated and BCG-unvaccinated children. Methods A cross-sectional study was conducted in FebruaryMarch 2011 on infants and children (aged 3 months to five years), who had household contact with adult pulmonary TB. We performed tuberculin (Mantoux) skin tests to detect TB infection in the children. Subjects were consisted of two groups: BCG-vaccinated and BCG-unvaccinated. Results Subjects were 100 children (50 BCG-vaccinated and 50 BCG-unvaccinated subjects). Positive Mantoux test results were observed in 9 vaccinated subjects and 33 unvaccinated subjects. The mean diameters of induration in the vaccinated and unvaccinated groups were 7.6 mm and 9.6 mm, respectively (95%CI of difference -4.25 to 0.20; P=0.074). In children who had household contact with sputum smear-positive adult pulmonary TB, BCG vaccination was a protective factor against TB infection, with an odds ratio (OR) of 0.113 (95%CI 0.045 to 0.286; P=0.0001). There were no significant differences in Mantoux test induration associated with nutritional status, age, type of TB contact, and duration since BCG vaccination, between the two groups. Conclusion BCG vaccination has a protective effect on TBexposed children, based on Mantoux test results. However, there are no differences in Mantoux test induration associated withÂ nutritional status, age, type of TB contact, or duration since BCG vaccination, between the BCG-vaccinated and BCGunvaccinated groups.

Association between passive smoking and Mycobacterium tuberculosis infection in children with household TB contact Novaily Zuliartha; Ridwan M. Daulay; Melda Deliana; Wisman Dalimunthe; Rini Savitri Daulay
Paediatrica Indonesiana Vol 55 No 1 (2015): January 2015
Publisher : Indonesian Pediatric Society

Background Tuberculosis (TB) and cigarette consumption are relatively high in Indonesia. Passive smoking may increase the risk of infection and disease in adults and children exposed to TB. An association between passive smoking and Mycobacterium tuberculosis infection in children has not been well documented. Objective To assess for an association between passive smoking and M. tuberculosis infection in children who had household contact with a TB patient. Methods This cross-sectional study was conducted in February and March 2011. Children aged 5 to 18 years who had household contact with a TB patient underwent tuberculin testing for M. tuberculosis infection. Subjects were divided into two groups: those exposed to passive smoke and those not exposed to passive smoke. Chi-square test was used to assess for an association between passive smoking and M. tuberculosis infection. Results There were 140 children enrolled in this study, with 70 exposed to passive smoke and 70 not exposed to passive smoke. Prevalence of M. tuberculosis infection was significantly higher in the passive smoking group than in those not exposed to passive smoke [81.4% and 52.9%, respectively, (P= 0.0001)]. In the passive smoking group there were significant associations between nutritional state, paternal and maternal education, and M. tuberculosis infection. But no associations were found between M. tuberculosis infection and familial income or BCG vaccination. Conclusion Among children who had household contact with a TB patient, they who exposed to passive smoke are more likely to have M. tuberculosis infection compared to they who not exposed to passive smoke.

Mantoux tests of children in household contact with adult acid fast bacilli-positive or -negative pulmonary tuberculosis Wardah Wardah; Ridwan Muktar Daulay; Emil Azlin; Wisman Dalimunthe; Rini Savitri Daulay
Paediatrica Indonesiana Vol 57 No 6 (2017): November 2017
Publisher : Indonesian Pediatric Society

Background Tuberculosis (TB) is the leading cause of mortality and morbidity in developing countries. In children, the major source of TB transmission is adults with pulmonary TB who have acid fast bacilli (AFB)-positive sputum. However, tuberculosis infection can also occur in children in household contact with adults who have AFB-negative pulmonary TB. Objective To compare Mantoux test results and induration diameters in children with adult pulmonary TB household contact who were either positive or negative for AFB, and to assess for possible associations between Mantoux test results with age, family income, and house ventilation in both groups. Methods A cross-sectional study was conducted from January to March 2014. Mantoux test was performed in children aged 3 months to 18 years who had household contact with either AFB-positive or -negative adult pulmonary TB patients. Results A total of 106 children were enrolled in the study. All subjects had household contact with adult pulmonary TB patients who were either AFB-positive (54 children) or AFB-negative (52 children). Mean Mantoux test induration diameters were significantly different between groups (10.9 (SD 6.55) mm vs. 6.2 (SD 5.91) mm, respectively; P=0.001). In addition, there was significantly higher risk of positive Mantoux test in children in contact with adult AFB-positive TB patients than in the AFB-negative group (OR 5.66; 95%CI 2.36-13.59; P=0.0001). However, there were no significant differences in positive Mantoux test results in each of the AFB-positive and -negative groups, with regards to age, family income, or house ventilation. Conclusion Mean Mantoux test induration diameter in children who had household contact with AFB-positive adults is significantly larger than that of the AFB-negative group. Positive Mantoux test results in children are associated with AFB-positive adult TB in the household. There is no association between positive Mantoux test results and age, family income, or house ventilation in both groups. Â

Decreased peak expiratory flow in pediatric passive smokers Fitri Yanti; Muhammad Ali; Ridwan M. Daulay; Wisman Dalimunthe; Rini Savitri Daulay
Paediatrica Indonesiana Vol 51 No 4 (2011): July 2011
Publisher : Indonesian Pediatric Society

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.14238/pi51.4.2011.198-201

Background Indonesia ranks fifth among countries with the highest aggregate levels of tobacco consumption in the world. Infants and children exposed to environmental tobacco smoke have increased rates of asthma, respiratory and ear infections, as well as reduced lung function. The effects of tobacco smoke exposure on lung function in children have been reported to be dependent on the source of smoke and the length and dose of exposure. Lung function may also be affected by a childâ€™s gender and asthma status.Objective To compare peak expiratory flow (PEF) in pediatric passive smokers to that of children not exposed to second hand smoke, and to define factors that may affect PEF in passive smokers.Methods In August 2009 we conducted a cross-sectional study at an elementary school in the Langkat district. Subjects were aged 6 to 12 years, and divided into two groups: passive smokers and those not exposed to secondhand smoke. Subjectsâ€™ PEFs were measured with a Mini-Wright peak flow meter. Measurements were performed in triplicate with the highest value recorded as the PEF. Demographic data including age, sex, weight, height, family income, parental education levels and occupations were obtained through questionnaires.Results Of the 170 participants, 100 were passive smokers and 70 were not exposed to secondhand smoke. Age distribution, weight and height were similar in both groups. We observed a significant difference in PEFs between the group of passive smokers and the group not exposed to secondhand smoke, 211.3 L/minute (SD 61.08) and 242.7 L/minute (SD 77.09), respectively (P < 0.005). The number of years of exposure to smoke (P = 0.079) and the number of cigarettes smoked daily in the household (P = 0.098) did not significantly influence PEF.Conclusion The PEF in pediatric passive smokers was significantly lower than that of children not exposed to secondhand smoke. PEF in passive smokers was not influenced by the number of years of smoke exposure or the number of cigarettes smoked daily in the household.

Tuberculosis risk factors in children with smear-positive tuberculosis adult as household contact Nora Hajarsjah; Ridwan M. Daulay; Oke Rina Ramayani; Wisman Dalimunthe; Rini Savitri Daulay; Fathia Meirina
Paediatrica Indonesiana Vol 58 No 2 (2018): March 2018
Publisher : Indonesian Pediatric Society

Background Children in household contact of adults with smear-positive tuberculosis (TB) are at higher risk of TB infection. Screening of these children is a main strategy for eliminating childhood TB.Objective To determine risk factors of TB among children in household contact with smear-positive adult TB patients.Methods This case-control study was conducted in 5 public health centers at Batu Bara District, North Sumatera. We studied children from birth to 18 year-old living in the same house as adults with smear-positive TB. A tuberculosis scoring system was used to diagnosis TB in the children. Associations between risk factors and the incidence of TB were analyzed using Chi-square, Mann-Whitney U, and logistic regression tests.Results We enrolled 145 children who had household contact with smear-positive adult TB patients. Subjects were allocated to either the case group [TB score >6; 61 subjects (42.0%)] or the control group [TB score <6; 84 subjects (58.0%)]. Bivariate analysis revealed that nutritional status, immunization status, number of people in the house, sleeping in the same bed, and duration of household contact had significant associations with the incidence of TB. By multivariate logistic regression analysis, nutritional status and duration of household contact were significant risk factors for TB, with OR 5.89 and 8.91, respectively.Conclusion Malnutrition and duration of household contact with smear-positive adult TB patients of more than 6 hours per day were risk factors for TB among children.

Tuberkulosis laten pada anak Flora Mindo Panjaitan; Ridwan M. Daulay; Wisman Dalimunthe; Rini Savitri Daulay
Majalah Kedokteran Nusantara The Journal Of Medical School Vol 46, No 1 (2013): The Journal of Medical School
Publisher : Fakultas Kedokteran USU

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Nowadays, TB continues to be a major health problem and a global public health issue. Latent tuberculosis is the clinical state characterized by the presence of lasting mycobacteria specific T-cell responses, assessed by tuberculin skin test (TST), in case of the absence of clinical and radiological manifestation of tuberculosis. Detection and treatment of latent tuberculosis is a key strategy in the control of TB. The Quantiferon TB Gold and T-Spot TB did not show higher sensitivity neither specificity than TST in detection latent TB in children. Tuberculin skin test is remain a recommended method to diagnose latent TB in children. Keywords : latent tuberculosis; children

Penanda infeksi bakteri pada pneumonia anak Wardah .; Nurjannah .; Bakhtiar .; Rini Savitri Daulay
Majalah Kedokteran Nusantara The Journal Of Medical School Vol 46, No 2 (2013): The Journal of Medical School
Publisher : Fakultas Kedokteran USU

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Pneumonia is the main health problem and the major causes of children’s death, particularly in children under five years old. Etiology of pneumonia are varried but it is very difficult to identify the etiology of pneumonia in children. The examination of lung’s secretory is very difficult to be performed in children. The examination of leucocyte, erythrocyte sedimentation rate, C-reactive protein and procalcitonin level can be used as bacterial infection’s marker to be treated with antibiotics. In addition, procalcitonin clinically proven more sensitive and spesific to identifying the infection caused by bacteria, compare to another marker.Keywords : pneumonia; children; marker; procalcitonin

Potential risk factors of pediatric acute respiratory distress syndrome in sepsis Saragih, Kezia Theofani; Malisie, Ririe Fachrina; Daulay, Rini Savitri; Sitepu, Bobby Ramses Erguna
Paediatrica Indonesiana Vol. 64 No. 3 (2024): May 2024
Publisher : Indonesian Pediatric Society

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.14238/pi64.3.2024.193-201

Background Sepsis in children is characterized by a dysregulated host response to infection and life-threatening organ dysfunction. Pediatric acute respiratory distress syndrome (PARDS) is a severe complication of sepsis. Several known risk factors of PARDS are immunodeficiency, obesity, source of infection, and genetic factors. Objective To describe the potential risk factors of PARDS in septic children at Haji Adam Malik General Hospital, Medan, North Sumatera. Methods This descriptive study using eligible medical record data from sepsis patients aged 1 month – 18 years was conducted at Haji Adam Malik General Hospital in 2020–2022. A total sampling method was used for subject selection. Patients’ demographic and clinical characteristics, mechanical ventilation modes and parameters, laboratory results, and outcomes were collected from medical records. Patients were classified as having sepsis with PARDS if Pediatric Acute Lung Injury Consensus Conference (PALICC) criteria of ARDS was met. Results Of 112 pediatric sepsis patients, 33.9% developed PARDS. The mortality rates for PARDS was 73.7%. Of the patients with PARDS, 57.9% had immunodeficiency, 60.5% patients had an intrapulmonary infection, 39.5% had an extrapulmonary infection, and 23.7% of patients had a suspected genetic disorder. In addition, 39.5% had good nutritional status, followed by 21.1% with obese. Conclusion The majority of patients with PARDS have intrapulmonary infection and immunodeficiency. Some of patients with PARDS have suspected genetic disorders and well nourished.

HUBUNGAN PEMBELAJARAN DARING MASA PANDEMI COVID-19 TERHADAP STRES SISWA SMA NEGERI 1 MEDAN Hia, Sukmawati; Adriztina, Indri; Wahyuni, Arlinda Sari; Amin, Mustafa Mahmud; Daulay, Rini Savitri
Jurnal Al Ulum LPPM Universitas Al Washliyah Medan Vol. 12 No. 1 (2024): Jurnal Al Ulum
Publisher : UNIVERSITAS AL WASHLIYAH (UNIVA) MEDAN

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.47662/alulum.v12i1.590

Pandemi Covid-19 telah memberikan dampak besar pada sistem pendidikan di seluruh dunia. Pembatasan sosial dan fisik yang diterapkan untuk memutus rantai penularan virus telah memaksa institusi pendidikan untuk beralih ke pembelajaran daring. Meskipun pembelajaran daring jauh lebih aman dari segi kesehatan, ini telah membawa tantangan baru bagi siswa, di mana mereka harus menyesuaikan diri dengan lingkungan belajar yang berbeda dan menavigasi kurikulum baru melalui platform virtual serta kurangnya interaksi langsung dengan guru dan teman sekelas, dan tuntutan akademis yang lebih berat di rumah. Jenis penelitian ini bersifat kuantitatif dengan desain penelitian cross sectional yang dilaksanakan di Sekolah Menengah Atas Negeri 1 Kota Medan. Sampel dalam penelitian ini sebanyak 158 siswa. Metode analisis data dalam penelitian ini menggunakan analisis regresi logistik. Hasil penelitian menunjukkan terdapat pengaruh variabel pengaruh yang signifikan (p<0,05) antara variabel pembelajaran daring terhadap variabel stres pada siswa pada masa pandemi Covid-19.

Drug-resistant Tuberculosis in Pediatric: A Case Report Lubis, Halisyah Hasyim; Daulay, Rini Savitri
Asian Australasian Neuro and Health Science Journal (AANHS-J) Vol. 5 No. 03 (2023): AANHS Journal
Publisher : Talenta Universitas Sumatera Utara

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.32734/aanhsj.v5i03.14329

Introduction:Â Drug-resistant tuberculosis (DR TB) is a condition where Mycobacterium tuberculosis is resistant to isoniazid, rifampicin or resistant to isoniazid and rifampin as well as other first-line anti-tuberculosis drugs (OAT). Tuberculosis (TB) is a contagious infectious disease, caused by Mycobacterium tuberculosis germs where the source of transmission is through droplets containing TB germs. Case Report: A 10 years 7 months girl, came to the MDR Polyclinic at the Haji Adam Malik Medan Central General Hospital (RSUP HAM Medan) on March 21 2023 bringing the results of the TB Molecular Rapid Test (TCM-TB) examination from the Teladan Barat Health Center with Rifampicin results were resistant and on March 24 2023 the patient was hospitalized. Currently, the patient is complaining of a cough that has been experiencing for Â± 3 weeks. Cough with the impression of a dry cough and is continuous so that it interferes with daily activities. The cough does not improve even though the patient has taken cough medicine. There is no fever, there is also no history of previous fever. According to the anamnesis from the patient's parents, there has been a weight loss in the last 2 months, around Â± 4 kg. There is no family history of long-term cough, but according to parents, there is a neighbor of the patient who suffers from pulmonary TB and is undergoing treatment. Discussion:Â After the diagnosis of drug-resistant tuberculosis is confirmed, an evaluation is carried out whether the patient meets the criteria for drug-resistant TB treatment guided by short-term or long-term oral drug-resistant tuberculosis. Patients who meet the evaluation criteria for treatment can immediately be given short-term oral drug-resistant tuberculosis therapy. If the patient does not meet the criteria for short-term treatment, long-term drug-resistant tuberculosis treatment is given. Routine evaluations are carried out during treatment and when the results of drug sensitivity tests are available, treatment is adjusted according to the examination results. Conclusion: A case of drug-resistant tuberculosis in a girl aged 10 years 7 months has been reported which was diagnosed based on anamnesis, physical examination, and supporting examinations, there was also a history of close contact with TB sufferers, and the results of TCM examination of sputum fluid showed rifampicin resistant MTB growth. Patients are treated as drug-resistant TB cases with a short-term regimen with regular monitoring of treatment response and side effects. Â Â

Co-Authors Bakhtiar Bakhtiar Bobby Ramses Erguna Sitepu Emil Azlin Fadilah Harahap Fathia Meirina, Fathia Fitri Yanti Flora Mindo Panjaitan Harahap, Juliandi Hia, Sukmawati Indri Adriztina Kusumawati, R. Lia Lubis, Halisyah Hasyim Malisie, Ririe Fachrina Mayasri, Fadhliani Mayasri, Fadhliani Putri Melda Deliana Muhammad Ali Muhammad Ali Mustafa Mahmud Amin Nora Hajarsjah Novaily Zuliartha Nurjannah . Oke Rina Ramayani OLGA RASIYANTI SIREGAR, OLGA RASIYANTI Pasaribu, Hotma Partogi Pertin Sianturi Riano, Dwika Intania Ridwan M. Daulay Ridwan M. Daulay Ridwan M. Daulay Ridwan M. Daulay Ridwan Muktar Daulay Rina Amelia Samodra, Yoseph Leonardo Saragih, Kezia Theofani Siagian, Beby Febyola Sinaga, Bintang Yinke Magdalena Siregar, Jelita Tako, Frida Welhelmina Tanjung, Ika Citra Dewi Wahyuni, Arlinda Sari Wardah . Wardah Wardah Wisman Dalimunthe Wisman Dalimunthe Wisman Dalimunthe Wisman Dalimunthe Wisman Dalimunthe, Wisman

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