Article Per Year (5 Year)
p-Index From 2021 - 2026
0.444
P-Index
This Author published in this journals
All Journal Jurnal Kedokteran Diponegoro Medica Hospitalia Magna Neurologica
Hexanto Muhartomo, Hexanto
Unknown Affiliation
Dentistry Health Professions Immunology & microbiology Medicine & Pharmacology Neuroscience Nursing Public Health

Published : 3 Documents Claim Missing Document
Claim Missing Document
Check
Articles

Found 3 Documents
Search

 1 
THE RELATIONSHIP BETWEEN ESR, HEMATOCRIT, PLATELETS COUNT AND OUTCOME OF CNS TUMOR PATIENTS WHO RECEIVED CHEMOTHERAPY AT RSUP DR. KARIADI SEMARANG Budi, Hyasinta Paramita; Rahmawati, Maria Belladona; Budisulistyo, Trianggoro; Muhartomo, Hexanto
DIPONEGORO MEDICAL JOURNAL (JURNAL KEDOKTERAN DIPONEGORO) Vol 9, No 2 (2020): DIPONEGORO MEDICAL JOURNAL ( Jurnal Kedokteran Diponegoro )
Publisher : Faculty of Medicine, Diponegoro University, Semarang, Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (407.555 KB) | DOI: 10.14710/dmj.v9i2.27097

Abstract

Background : Central nervous system tumors, both primary and secondary tumor, are malignancies which result in mental disorder, and neurological deficit. Therefore, the patients can end up being social burden for their environment. Hematological laboratory test including ESR, hematocrit, and platelets count are very practical. However, they are functional for predicting outcome. Aim: The current study aimed to determine the relationship between ESR, hematocrit, platelets count, and outcome of CNS tumor patients who received chemotherapy at RSUP dr. Kariadi Semarang. Method : This recent study was conducted at Medical Record Installation by collecting data from patient’s medical record. Data taken by researcher were hematologic profile (ESR, hematocrit, and platelets count), demographic data (age, gender, type of tumor, symptomatic treatment, and comorbidity), and outcome. Data were analyzed using univariate analytical method to show data distribution, bivariate analytical method to determine the relationship with outcome, and multivariate analytical method to determine which variable had the most significant relation. Result : Bivariate analytical method using chi-square test showed insignificant p value for hematocrit (p=0,541 total data, p=0,960 case, p=0,518 control). Platelets count analysis didn’t give significant p value either (p=0,541 total, p=0,790 case, p=0,292 control). There were no data could be obtained about ESR. Conclusion : The current study showed no relationship between hematocrit and outcome, neither the relationship between platelets count and outcome.Keywords : ESR, hematocrit, platelets count, outcome
The Relationship Between Serum Folic Acid Levels With The Cognitive Function of The Elderly Hermanto, Hermanto; Muhartomo, Hexanto; Husni, Amin; Widiastuty, Maria Immaculata; Suryawati, Herlina; Wati, Arinta Puspita
Medica Hospitalia : Journal of Clinical Medicine Vol. 10 No. 2 (2023): Med Hosp
Publisher : RSUP Dr. Kariadi

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.36408/mhjcm.v10i2.891

Abstract

Background: Cognitive decline is a common condition that occurs in the elderly. One of the early indicators of senility is a decrease in cognitive function. Folic acid is thought to protect the arteries from damage because of homocysteine by converting homocysteine into cysteine and then excreted in the urine. Increased levels of homocysteine can interfere with vascular function and cause toxic effects on neurons thereby increasing the risk of cognitive decline. Objective: To determine the relationship between serum folic acid levels and cognitive function of the elderly. Method: Analytical descriptive research with a cross-sectional approach. The research subjects were the elderly who met the inclusion criteria and did not have exclusion criteria. The research was conducted from May to July 2022 at the Pucang Gading Nursing Home, Semarang. Serum folic acid levels were examined using the ELISA (Enzyme-linked immunosorbent assay) method. Cognitive function was assessed using the Indonesian version of the Montreal Cognitive Assessment (MoCA) simultaneously on the subject. Cognitive function is normal if the MoCA-INA value is ≥ 26 and it is said to be cognitive dysfunction if the MoCA-INA value is < 26. Data were analyzed using the Spearman test. Results are considered significant if the value of p <0.05.  Result: There is a strong positive correlation between serum folic acid levels and cognitive function in the elderly (r=0.914, p<0.001). There is a relationship between educational level and cognitive function (r=0.922, p<0.001) where higher education correlates with increased cognitive function in the elderly. Conclusion: There is a significant positive correlation between serum folic acid levels and cognitive function in the elderly
A 22-Years-Old Male with Tuberculoma of the Brain and Spinal Cord with Miliary Tuberculosis Simamora, Rosinondang Deolita; Retnaningsih; Pasmanasari, Elta Diah; Muhartomo, Hexanto
Magna Neurologica Vol. 3 No. 1 (2025): January
Publisher : Department of Neurology Faculty of Medicine Universitas Sebelas Maret

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.20961/magnaneurologica.v3i1.1782

Abstract

Background: Tuberculosis (TB) remains a significant health issue in Indonesia. Central nervous system (CNS) tuberculoma is one of the extrapulmonary TB diseases and accounts for approximately 1% of all cases. The emergence of this disease is primarily associated with a weakened immune system. However, several other factors, such as comorbidities, a history of inadequate TB treatment, and poor nutrition, also play a role in the development of tuberculoma. Case: A 22-year-old male complained of weakness in all four limbs for the past month, accompanied by tingling and numbness from both feet up to the T10-11 dermatome level. The patient has a history of seizures from one year ago, interrupted treatment for military tuberculosis, and malnutrition. An MRI of the head and whole spine with contrast revealed tuberculomas. The patient was treated with medication, including intravenous dexamethasone 5 mg every 8 hours, oral phenytoin 200 mg every 24 hours, and anti-tuberculosis therapy. Discussion: Tuberculoma in the central nervous system is rare, especially multiple tuberculomas co-occurring in the brain and spinal cord. MRI is a sensitive tool for diagnosing tuberculomas, characterized by the presence of a target sign. The combination of corticosteroids, antiepileptic drugs, and an entire course of anti-tuberculosis medications aims to address both the immediate neurological symptoms and the underlying infection. Conclusion: TB can present as lesions in the brain and spinal cord, requiring the ability to correlate clinical manifestations and radiological features to establish a diagnosis and necessitating adequate therapy.
Co-Authors Amin Husni Arinta Puspita Wati, Arinta Puspita Budi, Hyasinta Paramita Budisulistyo, Trianggoro Hermanto Hermanto Pasmanasari, Elta Diah Rahmawati, Maria Belladona Retnaningsih Simamora, Rosinondang Deolita Suryawati, Herlina Widiastuty, Maria Immaculata