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All Journal Jurnal Penyakit Dalam Indonesia Neurona Acta Neurologica Indonesia
Delarosa, Dinda Olinda
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Health Professions Medicine & Pharmacology Neuroscience Public Health

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Lactate/Albumin Ratio as a Predictor of Mortality in Patients with Sepsis and Septic Shock: A Meta-Analysis Study Baihaqi, Fahri Ahmad; Delarosa, Dinda Olinda; Ramadhan, Rezki
Jurnal Penyakit Dalam Indonesia Vol. 9, No. 3
Publisher : UI Scholars Hub

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Abstract

Introduction. The lactate/albumin ratio is an inflammatory biomarker that has been widely used and suggested as a predictor of mortality in patients with sepsis and septic shock. However, the results are inconsistent. This meta-analysis aimed to evaluate the prognostic value of lactate/albumin ratio as a predictor of mortality in patients with sepsis and septic shock.Methods. The study protocol was registered with PROSPERO (CRD42021286242). A literature search was performed using PubMed, Ovid EMBASE, Ovid MEDLINE, SCOPUS, and Web of Sciences to find all studies evaluating the association between lactate/albumin ratio and mortality in patients with sepsis and septic shock. Meta-analysis was performed to synthesize the overall Standardized Mean Difference (SMD) of the lactate/albumin ratio and the pooled Odds Ratio (OR) for mortality with 95% confidence intervals (95% CI). Heterogeneity was assessed using I2. Publication bias was assessed quantitatively with Egger’s test. Analysis was performed using Stata version 16.Results. Seven studies (n=10,264 patients) were included in the meta-analysis. The meta-analysis results showed that non-survivor had a higher lactate/albumin ratio than survivor (random-effects model; SMD 1.47; 95% CI 0,91-2,04; p <0.001). Higher lactate/albumin ratio was associated with an increased mortality in sepsis and septic shock patients (fixed-effects model; OR 1.49 (95% CI 1.37-1.62); p <0.001).Conclusions. High lactate/albumin ratio was associated with mortality in sepsis and septic shock patients. Thus, lactate/albumin ratio can be used as a predictor biomarker in predicting mortality for sepsis and septic shock patients.
Faktor Risiko Stroke pada Pasien Penyakit Ginjal Kronik di RSUP dr. Sitanala Tangerang Delarosa, Dinda Olinda
Majalah Kedokteran Neurosains Perhimpunan Dokter Spesialis Saraf Indonesia Vol 39 No 3 (2022): Vol 39 No 3 (2022)
Publisher : PERDOSNI

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.52386/neurona.v39i3.234

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Introduction: Chronic Kidney Disease (CKD) is an independent risk factor in cardiovascular disease, leading to stroke incidence. The risk of stroke increased three to seven times in CKD stage 3 to 5 compared with the general population. Risk of stroke increases when the glomerulus filtration rate (GFR) decreases. Aim: This study is to know stroke risk factors in chronic kidney disease patients, especially at RSUP Dr Sitanala. Methods: This study was descriptive-analytic, a case-control study. Data were collected from the medical record from January 2021 to November 2021 at RSUP Dr Sitanala with purposive sampling based on inclusion and exclusion criteria. Data used univariate analysis, bivariate analysis with Chi-square, and logistic regression test. Results: From 100 samples showed that ten patients experienced a stroke. Woman (6%) was higher than man (4%). Hypertension was a higher risk factor (8%). CKD stage 5 was higher (9%) than other stages. Dyslipidemia and hyperuricemia had a significant relation statistically with stroke incidents in CKD patients. Hyperuricemia increased stroke 14 times in CKD patients. Conclusion: CKD is related to stroke by considering its severity based on CKD stages, hemodialysis, and underlying risk factors management.
Balancing Act: Exploring the Complexities of Drug Restriction Policies Ulwanda, Ramadhanti Salma; Nagpal, Chand Dhiraj; Delarosa, Dinda Olinda; Pradiptaloka, Ediva; Ririhena, Fiorentina Cemerlang; Siniwali, Ida Mas Ayu; Rahmadi, Ikhlas; Jeremia, Ivan; Saputri, Liana Alviah; Agustina, Lisa; Alsakina, Nashiha; Marwadhani, Sarah Shafa; Ni'am, Syauqi Faidhun; Pangeran, David
Acta Neurologica Indonesia Vol. 2 No. 02 (2024): Acta Neurologica Indonesia
Publisher : Departemen Neurologi Fakultas Kedokteran Universitas Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.69868/ani.v2i02.28

Abstract

Co-Authors Alsakina, Nashiha Baihaqi, Fahri Ahmad Jeremia, Ivan Lisa Agustina, Lisa Marwadhani, Sarah Shafa Nagpal, Chand Dhiraj Ni'am, Syauqi Faidhun Pangeran, David Pradiptaloka, Ediva Rahmadi, Ikhlas Ramadhan, Rezki Ririhena, Fiorentina Cemerlang Saputri, Liana Alviah Siniwali, Ida Mas Ayu Ulwanda, Ramadhanti Salma