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All Journal Indonesian Journal of Urology Jurnal Ilmu Kedokteran dan Kesehatan
Sherly Yuniarchan, Sherly
Unknown Affiliation
Biochemistry, Genetics & Molecular Biology Health Professions Immunology & microbiology Medicine & Pharmacology Public Health

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RISK FACTORS OF MORTALITY IN CHILDREN WITH WILMS’ TUMOR AT SOETOMO HOSPITAL SURABAYA Shanty, Maria Christina; Yuniarchan, Sherly; Andarsini, Mia Ratwita; Ugrasena, I Dewa Gede; Permono, Bambang; Prasetyo, Risky Vitria
Indonesian Journal of Urology Vol 26 No 2 (2019)
Publisher : Indonesian Urological Association

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.32421/juri.v26i2.469

Abstract

Objective: Wilms’ tumor is the most common childhood renal tumor for about 6% of pediatric malignant disease. The 5-year survival rate in United States increased from approximately from 70% (1970-1973) to 92% (1989-1996). This study was aim to analyze the risk factors of mortality in children with Wilms’ tumor. Material & Methods: A cross-sectional study was conducted in children with Wilms’ tumor at Soetomo Hospital during 2006-2011. The data of demographic, clinical profile, complete blood count, blood urea nitrogen, glomerular filtration rate, histological type, disease stage, metastases and relapse were analyzed as risk factors of mortality using logistic regression. Results: There were 37 Wilms’ tumor children and 5 children were excluded because of incomplete data. The mean age was 3.0 (SD 2.6) years, and male-to-female ratio was 2.5 : 1. There were 5/32 children in stage I, 7/32 children in stage II, 8/32 children in stage III, 11/32 children in stage IV, and 1/32 children in stage V. There were 15/32 children underwent operation. Complete remission occurred in 12/32 children and 1/32 children relapsed. There were 20/32 children died, associated with anemia (P=0.033, OR=6.111, 95% CI=1.056-35.352) and advanced stage (P=0.021, OR=8.000, 95% CI=1.575-40.632). The risk of mortality increased 3.284 folds with every increased stage (P=0.007, 95% CI=1.338-7.775). Conclusion: Disease stage is the significant risk factor of mortality in children with Wilms’ tumor.  
Profil Glomerulonefritis Akut Pasca Streptokokus (GNAPS) Pada Anak Di RSUD Abdoel Wahab Sjahranie Samarinda Cantika, Anindi Faraz; Fitriany, Evi; Yuniarchan, Sherly
Jurnal Ilmu Kedokteran dan Kesehatan Vol 12, No 7 (2025): Volume 12 Nomor 7
Publisher : Prodi Kedokteran Fakultas Kedokteran Universitas Malahayati

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.33024/jikk.v12i7.18823

Abstract

Glomerulonefritis akut pasca streptokokus (GNAPS) adalah peradangan akut pada ginjal yang muncul setelah infeksi Streptokokus β hemolitikus grup A pada saluran pernapasan atas atau kulit. Penelitian ini bertujuan untuk menggambarkan profil epidemiologi, klinis, dan hasil laboratorium pada pasien anak-anak dengan GNAPS yang dirawat di RSUD Abdoel Wahab Sjahranie Samarinda. Penelitian ini menggunakan metode observasional deskriptif dengan pendekatan retrospektif pada anak usia 0-18 tahun yang didiagnosis GNAPS antara Januari 2020 hingga Desember 2023. Data diambil dari rekam medik pasien, dengan total 32 pasien yang memenuhi kriteria penelitian. Hasil menunjukkan bahwa sebagian besar pasien berusia 6-10 tahun (53,1%), dengan mayoritas berjenis kelamin laki-laki (62,5%). Sebanyak 46,9% pasien memiliki status gizi normal, meskipun terdapat juga pasien dengan status gizi kurang dan buruk. Tanda klinis yang paling banyak ditemukan adalah edema (71,9%) dan hipertensi (71,9%). Pemeriksaan laboratorium menunjukkan hasil terbanyak berupa hematuria mikroskopik (90,6%), anemia (87,5%), dan peningkatan kadar ureum (81,2%). Mayoritas hasil ultrasonografi ginjal menunjukkan adanya abnormalitas pada struktur ginjal (62,5%). Gagal ginjal akut (21,9%) dan ensefalopati hipertensi (21,9%) merupakan komplikasi yang paling sering ditemukan.
Co-Authors Bambang Permono Cantika, Anindi Faraz Evi Fitriany I Dewa Gede Ugrasena Mia Ratwita Andarsini Risky Vitria Prasetyo Shanty, Maria Christina