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All Journal Indonesian Journal of Pharmaceutical Science and Technology Jurnal Fitofarmaka Indonesia As-syifaa Jurnal Farmasi Window of Health : Jurnal Kesehatan Jurnal Mandala Pengabdian Masyarakat Indonesian Community Journal Pharmaceutical Reports MPSJ
Muzakkir Baits, Muzakkir
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Agriculture, Biological Sciences & Forestry Biochemistry, Genetics & Molecular Biology Chemistry Computer Science & IT Economics, Econometrics & Finance Environmental Science Health Professions Immunology & microbiology Medicine & Pharmacology Nursing Public Health Social Sciences Other

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Journal : Window of Health : Jurnal Kesehatan

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Kersen (Cherry) (Muntingia calabura L) Leaves as an Alternative Plant Free Radical Scavenger in Improving the Immune System St. Maryam; Baits, Muzakkir; Tahir, Masdiana
Window of Health : Jurnal Kesehatan Vol 6 No 4 (October 2023)
Publisher : Fakultas Kesehatan Masyarakat Universitas Muslim Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.33096/woh.vi.703

Abstract

Kersen (Cherry) (Muntingia calabura L) leaves are empirically used to treat various diseases because they contain flavonoid and tannin compounds. Based on previous research, it was reported that phenolic compounds, tannins, and flavonoids can potentially counteract free radicals so that they can improve the body's immune system. The purpose of this study was to determine the antioxidant activity of extracts of methanol, ethyl acetate, and n-hexane from cherry leaves (Muntingia calabura L.). The DPPH free radical scavenging method is based on the reduction of the colored DPPH free radical methanol solution by free radical inhibition. The extraction process of a compound is carried out to separate the material from the mixture using a suitable solvent. The existence of a level of polarity of a solvent used to attract the components of active compounds in plants is a guide for the search for new compounds in a plant. The potential of a compound to counteract free radicals can be determined by calculating the IC50. The results showed that the extract of methanol, ethyl acetate, and n-hexane of the cherry leaf (Muntingia calabura L.) had inhibitory activity against DPPH free radicals with IC50 values of 8.67; 9,097, and 18.17 g/mL. Meanwhile, gallic acid has inhibitory activity with an IC50 value of 1.77 g/mL. Methanol and ethyl acetate extracts of cherry leaves were able to inhibit DPPH activity in a very strong category, which was almost comparable to gallic acid, while n-hexane extract had antioxidant activity in a strong category.
Co-Authors Abdul Malik aenung, nurul Amalia, Alifya Ananda, Savitri Anggrayni, Anggi Aris, Arru'nnisa Ika Nur Ilmi arniati, arniati Asriani Suhaenah Ayu Andini Dahlia, Andi Faradiba Harti Widiastuti Herwin Herwin, Herwin Ismail, Normawati Mamat Pratama, Mamat Masdiana Tahir, Masdiana Mochammad Imron Awalludin Muammar Fawwaz Muflihunna, A Nur Fadillah, Nur Nurhikmah Nurhikmah Nurung, Ayyub Harly Praditha, Elyana putri, Hemalia Rachmat Kosman, Rachmat Rahmawati, Rahmawati Rezky M, Mega Ririn Ririn Sari, Wina Astri St Maryam, St St. Maryam, St. Syam, Nurizzah Aulia Syarif, Rezki Tadjuddin Naid Trihadi, Andi Yenni Triana, Yenni Yusuf, Rudy Zainal Abidin