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Metode Analisis Natrium Benzoat pada Makanan dan Minuman: Literatur Review Erlangga Muhamad Prayuda; Febi Febriani Hasanah; Rika Valensia; Nurma Dwi Rahmawati; Marsah Rahmawati Utami
Journal of Pharmaceutical and Sciences JPS Volume 6 Nomor 2 (2023)
Publisher : Fakultas Farmasi Universitas Tjut Nyak Dhien

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (282.504 KB) | DOI: 10.36490/journal-jps.com.v6i2.38

Abstract

Preservatives are food additives that can inhibit the growth of microorganisms so that food does not get stale easily. Sodium benzoate is one of the preservatives that is allowed to be used in food but within a predetermined limit of <1 g / kg according to BPOM RI. The purpose of this review is to find out an overview and provide information about the method of analyzing sodium benzoate levels in food and comparing the results with the provisions. The method used is literature review from various journals with a span of 10 years. The results of this study, the method of analyzing sodium benzoate in food can be carried out qualitatively and quantitatively. Qualitative tests can use the addition of FeCl3, test kits, and KLT, while quantitative tests can use KCKT, spectrophotometry UV-Vis and titration. The samples studied from 11 journals obtained were syrup, sauce (tomato and chili), soy sauce, beverage and strawberry jam products produced industrially and/or home-produced. The conclusion of the various methods tested is that there are still many food producers who use sodium benzoate as a preservative, but not all samples studied are in accordance with the provisions
Metode Analisis Cemaran Mikroba pada Makanan : Review Artikel Aditia Putra Tama; Vina Luthfiana Hasna; Khamairah Azzahrawaani Hermawan; Marsah Rahmawati Utami; Lina Nurfadhila
Journal of Pharmaceutical and Sciences JPS Volume 6 Nomor 2 (2023)
Publisher : Fakultas Farmasi Universitas Tjut Nyak Dhien

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (202.837 KB) | DOI: 10.36490/journal-jps.com.v6i2.46

Abstract

Food is one of the important things in the sustainability of human life. The main function of food for humans is to meet the nutritional needs of the body, where these nutrients must be met according to gender, age, daily physical activity, and body weight. As the main and basic function of food itself, in order to be a good source of nutrients and energy, of course, the food must be ensured to be safe, clean, does not contain harmful food-enhancing ingredients, and is free from sources of disease. The source of this disease can arise from food that has been contaminated, one of which is food contaminated with microbial contamination. This article aims to inform the analysis of microbial contamination methods in various foods. The method used in writing this article review is to search for several references in the form of scientific journals or scientific articles from research with the keyword microbial contamination analysis.
Analisis Senyawa Obat Vankomisin dalam Plasma Darah dengan Berbagai Metode Elvira Julia elvira julia; Arline Rahmadianti Kusumawardhani; Anggraini Anggraini; Nolla Olipia Elva Megrian; Marsah Rahmawati Utami; Lina Nurfadhila
Journal of Pharmaceutical and Sciences JPS Volume 6 Nomor 2 (2023)
Publisher : Fakultas Farmasi Universitas Tjut Nyak Dhien

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (219.884 KB) | DOI: 10.36490/journal-jps.com.v6i2.138

Abstract

Vancomycin is one of antibiotic that used to treat infections caused by methicillin-resistant Staphylococcus aureus (MRSA). The recommended concentration for vancomycin is 15-20 mg/L every 8-12 hours in the blood. Vancomycin has a narrow therapeutic index so that small changes in dose can lead to significant changes in drug response. Therefore, monitoring of drug therapy is recommended to optimize vancomycin concentrations. Vancomycin levels in blood plasma have been measured using a variety of analytical techniques, the two that are most frequently employed are high performance liquid chromatography (HPLC) and immunoassay methods. This review intends to give information on the two analytical methods and what is appropriate to learn about the comparison of the two analytical methods on vancomycin levels in blood plasma. The results of the review that has been carried out are that the main difference between the HPLC method and the immunoassay is in the basic principles of the analytical technique. The immunoassay method (FPIA and RIA methods) is more appropriate to use than the HPLC method because it conforms the results of the analysis, especially in the range of concentrations and sensitivities obtained.