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Pengaruh Pemberian Obat Antidepresan terhadap Risiko Bunuh Diri: Literatur Review Febi Febriani Hasanah; Indah Laily Hilmi; Salman Salman
Journal of Pharmaceutical and Sciences JPS Volume 6 Nomor 2 (2023)
Publisher : Fakultas Farmasi Universitas Tjut Nyak Dhien

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (302.458 KB) | DOI: 10.36490/journal-jps.com.v6i2.37

Abstract

Depression is a mental health disorder that often occurs to anyone regardless of age. Treatment of depression can be done with psychotherapy, administration of antidepressants, or a combination of both. However, the use of antidepressants is believed to increase the risk of suicidal behavior and ideation, especially in adolescent patients. The purpose of this study was to determine the effect of antidepressant therapy on the risk of suicide in adolescents. This research was conducted using the Literature Review method using the Google Scholar database. Articles obtained from the search process were then re-selected based on inclusion and exclusion criteria, so that 5 articles that match the criteria were obtained. The results of the study show that giving antidepressant drugs to patients can increase or decrease the risk of suicide in patients. Patients aged <18 years (children and adolescents) are considered to have a greater risk of suicide compared to adult and geriatric patients. Based on these results, it can be concluded that the use of antidepressant drugs must be done wisely. Patients need to receive supervision and support from the closest people in using antidepressant drugs to avoid the risk of suicide in patients.
Metode Analisis Natrium Benzoat pada Makanan dan Minuman: Literatur Review Erlangga Muhamad Prayuda; Febi Febriani Hasanah; Rika Valensia; Nurma Dwi Rahmawati; Marsah Rahmawati Utami
Journal of Pharmaceutical and Sciences JPS Volume 6 Nomor 2 (2023)
Publisher : Fakultas Farmasi Universitas Tjut Nyak Dhien

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (282.504 KB) | DOI: 10.36490/journal-jps.com.v6i2.38

Abstract

Preservatives are food additives that can inhibit the growth of microorganisms so that food does not get stale easily. Sodium benzoate is one of the preservatives that is allowed to be used in food but within a predetermined limit of <1 g / kg according to BPOM RI. The purpose of this review is to find out an overview and provide information about the method of analyzing sodium benzoate levels in food and comparing the results with the provisions. The method used is literature review from various journals with a span of 10 years. The results of this study, the method of analyzing sodium benzoate in food can be carried out qualitatively and quantitatively. Qualitative tests can use the addition of FeCl3, test kits, and KLT, while quantitative tests can use KCKT, spectrophotometry UV-Vis and titration. The samples studied from 11 journals obtained were syrup, sauce (tomato and chili), soy sauce, beverage and strawberry jam products produced industrially and/or home-produced. The conclusion of the various methods tested is that there are still many food producers who use sodium benzoate as a preservative, but not all samples studied are in accordance with the provisions