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Empirical Antibiotic Therapy Assessment of Patients diagnosed with Sepsis in Intermediate Care Ward of Internal Medicine Department of Dr. Soetomo General Hospital according to Gyssens Method Adiwinoto, Ronald Pratama; Sustini, Florentina; Hardiono, Hardiono; Widodo, Agung Dwi Wahyu; Hidajat, Boerhan; Hadi, Usman
Oceana Biomedicina Journal Vol 1, No 2 (2018): Oceana Biomedicina Journal
Publisher : Universitas Hang Tuah

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (546.601 KB) | DOI: 10.30649/obj.v1i2.17

Abstract

Rational empirical antimicrobial therapy is an important component of sepsis patient management. This study aimed to assess the rationality of empirical antimicrobial therapy in patients diagnosed with sepsis admitted in intermediate care ward of internal medicine department (RPI) of Dr. Soetomo General Hospital from January 2016 to July 2017. Medical records of 91 patients diagnosed with sepsis were collected and studied retrospectively in period from July 2017 to November 2017. 91 (85.05%) medical records from 107 sepsis patients were evaluated. Cultures and antimicrobial sensitivity tests were carried out in 21 (23.07%) patients. 14 patients yielded positive culture results, 9 of which were MDRO positive with ESBL as resistant marker. Empirical antibiotic therapies for these patients were reviewed according to Gyssens method.73 (80.2%) of 91 patients were deemed receiving appropriate empirical antibiotic therapies. Ceftriaxone IV injection as monotherapy or combination therapy were the most common empirical antibiotic therapies (82 in 91 patients, 90.1%), despite local microbiologic flora and antibiogram show most pathogens were resistant to ceftriaxone. Mortality rate in this study was high, 92.3% (84 patients died) despite rational empirical antibiotic therapies were high. This study concluded that empirical antibiotic therapies in sepsis patients according to guidelines adopted in Soetomo General Hospital, albeit deemed rational, was no longer appropriate according to local antibiogram issued by microbiological department of Soetomo General Hospital. Keywords: Empirical Antibiotics Therapy, Gyssens criteria, Intermediate Care Ward, Sepsis, Septic Shock
SUMBER ETIKA DALAM ISLAM Hardiono, Hardiono
JURNAL AL-AQIDAH Vol 12, No 2 (2020)
Publisher : Universitas Islam Negeri Imam Bonjol Padang

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (738.742 KB) | DOI: 10.15548/ja.v12i2.2270

Abstract

In this paper, we will discuss the ethical problems generated by Islam as was directly exemplified by the pioneer, enlightener and role model of all followers, namely the Prophet Muhammad SAW. The source of ethics in Islam (Islamic ethics) is the al-Qur'an and the Sunnah, both of which are always a measure of the merits of the actions committed by the Muslims. These two sources are a guide for human life to achieve happiness in this world and in the hereafter.    The Prophet's behavior is the most factual interpretation of the Koran. In fact, in many narrations it is emphasized that the Prophet did not act / behave but because of the guidance of revelation, and the Prophet's morals were al-Qur'an. That is why in Islamic scholarship, including Islamic ethics, it does not give up its premises from the Qur'an and the Sunnah of the Prophet SAW. In Islam, the Quran and Sunnah will teach adherents from all sides, be it social, religious, cultural and so on. So in this paper we will discuss the sources of ethics in Islam (Islamic Ethics).            The method of this research is library research (library research), namely research that uses literature in the form of books, notes and reports on the results of previous research which will later become an analysis tool regarding ethics in Islam.     The conclusion of this paper is that the source of ethics in Islam is al-Quran and as-Assunah, which  will be the life guide for Muslims and non-Muslims to achieve true happiness, which the Prophet had exemplified directly from the above source.