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All Journal HAYATI Journal of Biosciences Indonesian Journal of Tropical and Infectious Disease Sari Pediatri Jesya (Jurnal Ekonomi dan Ekonomi Syariah) Oceana Biomedicina Journal Biomolecular and Health Science Journal JUXTA: Jurnal Ilmiah Mahasiswa Kedokteran Universitas Airlangga Indonesian Journal of Clinical Pathology and Medical Laboratory (IJCPML) CURRENT INTERNAL MEDICINE RESEARCH AND PRACTICE SURABAYA JOURNAL Indian Journal of Forensic Medicine & Toxicology Griya Journal of Mathematics Education and Application Narra J Folia Medica Indonesiana
Usman Hadi
Dept. Of Internal Medicine School Of Medicine Airlangga University/Dr. Soetomo Hospital
Agriculture, Biological Sciences & Forestry Biochemistry, Genetics & Molecular Biology Decision Sciences, Operations Research & Management Dentistry Earth & Planetary Sciences Education Health Professions Immunology & microbiology Mathematics Medicine & Pharmacology Neuroscience Nursing Public Health

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Medical Audit of the Management of Patients with Sepsis in the Intermediate Care Unit of Department Internal Medicine School of Medicine Airlangga University/Dr. Soetomo Hospital Hadi, Usman; Triyono, Erwin Astha
Indonesian Journal of Tropical and Infectious Disease Vol 1, No 1 (2010)
Publisher : Institute of Topical Disease

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Abstract

Sepsis and septic shock is one of the highest causes of death in patients treated in hospitals. Research Objectives: to evaluate the quality of the management of sepsis patients in Intermediate Care Unit, Department of Internal Medicine Dr. Soetomo Hospital Surabaya, Indonesia. This study was a retrospective study to re-evaluate the patient medical record. The number of patients treated: 275 patients, sepsis patients: 80 patients, the number of patients who entered the study 50 patients, 30 (60%) female and 20 (40%) men, most age groups aged 60 -70 years (32%), Mean 54 Median 56. Diagnostic accuracy according to the criteria of sepsis 45 (90%) patients, compliance with taking blood culture 2 (4%) patients, appropriate antibiotic selection 49 (98%) patients, the number of patients who should not be given antibiotics (4 patients), but given the antibiotic is 3 (75%) patients, the number of patients who should be given antibiotics (46 patients) but were not given antibiotics 1 (2%) patient. The reason of patients discharged: 27 had died (54%), 13 cured (26%), not yet recovered 10 (20%). The reason of patients discharged forcibly: to feel recovered 2 (20%), the condition gets worse 3 (30%), no cost 2 (20%), not clear 3 (30%). Patients with sepsis remain a big problem, and it still needs to improve the management of sepsis on existing guidelines.
PROBLEM OF ANTIBIOTIC USE AND ANTIMICROBIAL RESISTANCE IN INDONESIA: ARE WE REALLY MAKING PROGRESS? Hadi, Usman; Kuntaman, Kuntaman; Qiptiyah, Mariyatul; Paraton, Hari
Indonesian Journal of Tropical and Infectious Disease Vol 4, No 4 (2013)
Publisher : Institute of Topical Disease

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Background: Based on the results Antimicrobial Resistance in Indonesia: prevalence and prevention-study (AMRIN-study), the Ministry of Health of Indonesia in 2005 began a program antibiotic resistance control (PPRA) in some government hospitals, and is currently developing to all government teaching hospitals in Indonesia. Aim: The core activities of the PPRA are to implement standardized surveillance emergence of antibiotic resistant bacteria, and the surveillance of antibiotic use in terms of quantity and quality. Method: Our research in the years 2003 showed the proportion of antibiotic use 84% of patients in a hospital. The use of inappropriate antibiotics was very high, 42% no indication. Result: In 2012 the results of surveillance showed decline of inappropriate use of antibiotic, but prevalence extended-spectrum b-lactamase (ESBL)-producing K.pneumoniae (58%), and E.coli (52%) andmethicillin-resistant S.aures (MRSA) (24%) were increasing. Conclusion: It was needed to implement the most appropriate programs to prevent the growth and development of bacteria resistant to antibiotics.
Empirical Antibiotic Therapy Assessment of Patients diagnosed with Sepsis in Intermediate Care Ward of Internal Medicine Department of Dr. Soetomo General Hospital according to Gyssens Method Adiwinoto, Ronald Pratama; Sustini, Florentina; Hardiono, Hardiono; Widodo, Agung Dwi Wahyu; Hidajat, Boerhan; Hadi, Usman
Oceana Biomedicina Journal Vol 1, No 2 (2018): Oceana Biomedicina Journal
Publisher : Universitas Hang Tuah

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (546.601 KB) | DOI: 10.30649/obj.v1i2.17

Abstract

Rational empirical antimicrobial therapy is an important component of sepsis patient management. This study aimed to assess the rationality of empirical antimicrobial therapy in patients diagnosed with sepsis admitted in intermediate care ward of internal medicine department (RPI) of Dr. Soetomo General Hospital from January 2016 to July 2017. Medical records of 91 patients diagnosed with sepsis were collected and studied retrospectively in period from July 2017 to November 2017. 91 (85.05%) medical records from 107 sepsis patients were evaluated. Cultures and antimicrobial sensitivity tests were carried out in 21 (23.07%) patients. 14 patients yielded positive culture results, 9 of which were MDRO positive with ESBL as resistant marker. Empirical antibiotic therapies for these patients were reviewed according to Gyssens method.73 (80.2%) of 91 patients were deemed receiving appropriate empirical antibiotic therapies. Ceftriaxone IV injection as monotherapy or combination therapy were the most common empirical antibiotic therapies (82 in 91 patients, 90.1%), despite local microbiologic flora and antibiogram show most pathogens were resistant to ceftriaxone. Mortality rate in this study was high, 92.3% (84 patients died) despite rational empirical antibiotic therapies were high. This study concluded that empirical antibiotic therapies in sepsis patients according to guidelines adopted in Soetomo General Hospital, albeit deemed rational, was no longer appropriate according to local antibiogram issued by microbiological department of Soetomo General Hospital. Keywords: Empirical Antibiotics Therapy, Gyssens criteria, Intermediate Care Ward, Sepsis, Septic Shock
Varicella Pneumonia in an Elderly Patient Isidro Lumanpauw; Usman Hadi
Indian Journal of Forensic Medicine & Toxicology Vol. 15 No. 4 (2021): Indian Journal of Forensic Medicine & Toxicology
Publisher : Institute of Medico-legal Publications Pvt Ltd

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.37506/ijfmt.v15i4.16918

Abstract

Varicella pneumonia is a common complication in adults, while it is a mild and self-limiting disease inchildren. Elderly patients may have severe manifestations compared to adults due to the weakening oftheir immune system in clearing the virus. Treatment with intravenous acyclovir and varicella-zosterimmunoglobulin (VZIG) offers a good prognosis, while the use of steroids is still debated. Despite standardmanagement, our case presents a fatality in an older woman with varicella pneumonia.
Physical Exercise in Clinical Stage IIhuman Immunodeficiency Virus Infection Patients’ Increasesskeletal Muscle MAss Through the Increasing of Myogenic Regulatory Factors Expression Sri Mardjiati Mei Wulan; Hening Laswati; Usman Hadi; Nasronudin Nasronudin
Indian Journal of Forensic Medicine & Toxicology Vol. 15 No. 4 (2021): Indian Journal of Forensic Medicine & Toxicology
Publisher : Institute of Medico-legal Publications Pvt Ltd

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.37506/ijfmt.v15i4.17091

Abstract

Background: Human Immunodeficiency Virus infection is a chronic diseasethat threatensthe health ofmillionsof people inthe worldand causing disability. One of the factors that causedisabilityis HIVmusclewasting,causing a decrease inthe quality of lifethat interferethe daily activitiesand evenincreased mortality. Properphysical exercise is needed to prevent and treat muscle wasting.Methods: This studyusinghuman subjectswithclinicalstageII HIVinfection. Subjectswere groupedinto two:Intervention (n =9) that subjects whogetmoderate-intensity physicalexercise (HIVA) for 8weeks andControl (n=9) as subjects wereobservedfor 8 weeks. Muscles samples were taken fromthe vastuslateralismusclebiopsiesthat performed24 hoursafterthe lastphysical exercise,immunohistochemicalexaminationwithmonoclonalantibodyanti-Pax7, anti-MyoD1 andanti-myogenin and measurement of thigh circumference.Results: Therewere significant increase in regeneration of skeletal muscle in the intervention group(increasing of Pax7, MyoD1 and myogenin) than the control groupand significant increase in quadricepsmuscles mass as measured by thigh circumference (p < 0.001).Conclusion: HIVA physical exerciseof moderate intensityincreasesskeletal muscleregenerationinclinicalstageII HIVinfectionthroughthe increasingPax7, MyoD1, myogeninexpression and followed by an increaseof quadriceps muscles mass.
Post Traumatic Tuberculous Tenosynovitis in a Patient that Manifests as Soft Tissue Tumor: A Case Report Haryo N. Yahya; Hadi, Usman
Indian Journal of Forensic Medicine & Toxicology Vol. 16 No. 1 (2022): Indian Journal of Forensic Medicine & Toxicology
Publisher : Institute of Medico-legal Publications Pvt Ltd

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.37506/ijfmt.v16i1.17554

Abstract

Mycobacterium tuberculosis infection is one of the oldest diseases of the human race. This bacteriacan attack any organ in the human body. Extra Pulmonary Tuberculosis (EPTB) infection diagnosis arerarely straightforward, and in many cases, delayed due to various reasons. Tuberculous tenosynovitis(inflammation of the tendon and its capsule because of Mycobacterium tuberculosis complex infection)is a rare form of EPTB. Tuberculosis infection at sites of previous trauma have been reported consistentlythough rarely. We present the case of a 48 years old male with complains of lumps on his lower left arm(with prior history of blunt trauma on the location) and progressive inability to flex the fingers of his lefthand. Early examinations suggest the diagnosis to be a soft tissue tumour. However, tissue biopsy latershowed that the patient was actually suffering from tuberculosis infection. The patient later showedsatisfying response to tuberculosis medication on subsequent follow ups.
Successful Treatment of Cerebral Tuberculoma and Tuberculous Lymphadenitis in an HIV/AIDS Patient: A Case Report Tenta Hartian Hendyatama; Usman Hadi
Indian Journal of Forensic Medicine & Toxicology Vol. 16 No. 1 (2022): Indian Journal of Forensic Medicine & Toxicology
Publisher : Institute of Medico-legal Publications Pvt Ltd

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.37506/ijfmt.v16i1.17654

Abstract

Tuberculosis is one opportunistic infection that may occur in HIV/AIDS patients. Its clinical presentation may depend on infected organs. A 37-years old man complained of left limb weakness followed by mild fever, weight loss of more than 10 kgs within two months, and swelling in his left submandibular region. Laboratory tests showed mild anemia, hypoalbuminemia, and positive serology HIV test. Histopathological examination of neck swelling showed inflammation of chronic granulomatous tuberculous with acid-fast bacilli positive in Ziehl Nielsen staining. Head CT scan with contrast, showed multiple isodense lesions with rim contrast enhancement accompanied by perifocal edema. Anti-Tuberculosis Drug and Anti-Retroviral Therapy were given as a combination treatment for this patient. Clinical and radiological improvement in the patient indicated good outcome and successful treatment.
A Patient with AIDS and Embolic Stroke: A Case Report Troy Fonda; Usman Hadi
Indian Journal of Forensic Medicine & Toxicology Vol. 16 No. 1 (2022): Indian Journal of Forensic Medicine & Toxicology
Publisher : Institute of Medico-legal Publications Pvt Ltd

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.37506/ijfmt.v16i1.17656

Abstract

Human immunodeficiency virus (HIV) infection is a global concern. Globally, 36.7 million people are living with HIV and 1 million people died at the end of 2016. There is an association between human immunodeficiency virus (HIV) infection with neurological manifestations. Between 1% and 5% of patients with HIV develop stroke. The pathogenesis of AIDS with stroke is still controversial. A 37-year-old male patient with AIDS had an embolic stroke. The diagnosis of the patient was based on clinical condition and the CT scan results of the head with contrast. The stroke-causing mechanism in patients is HIV-associated vasculopathy that results from accelerated atherosclerosis. After administration of antiplatelet and statin, the patient’s condition improves.
Predictor of Mortality COVID-19 in Two Referral Hospital in Surabaya, Indonesia Usman Hadi; Bramanton; Tri Pudy Asmarawati; Musofa Rusli; Nasronudin; Brian Eka Rachman; M. Vitanata Arfijanto
Indian Journal of Forensic Medicine & Toxicology Vol. 16 No. 1 (2022): Indian Journal of Forensic Medicine & Toxicology
Publisher : Institute of Medico-legal Publications Pvt Ltd

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.37506/ijfmt.v16i1.17659

Abstract

Introduction: World Health Organization had identified COVID-19 in January 2019. This disease is caused by SARS-CoV-2, which spread throughout the world and became a pandemic on March 20, 2020. COVID-19 is still a health problem because it has not clear whether the patients will be cured and survive from the disease or not. This study aims to determine the predictors of mortality from COVID-19 at Dr. Soetomo General Academic Hospital and Universitas Airlangga Hospital in Surabaya, Indonesia.Method: This study was conducted in Dr. Soetomo General Academic Hospital (referral hospital for COVID-19, 1500 beds) and Universitas Airlangga Hospital (Referal Hospital for COVID-19, 600 beds). The study used data on patients with confirmed COVID-19 who were hospitalized at these two referral hospitals. Predictors of mortality were analyzed using logistic regressions.Result: There were 247 COVID-19 patients enrolled in this study, all patients were tested positive PCR SARS-CoV-2. The main complaints were cough, nasal congestion, dyspnea, and fever. Significant predictor mortality in this study were age >60 years old (OR: 3.24, 95% CI, 1.36 - 7.70), chronic kidney disease (OR: 5.71, 95% CI, 2.05 - 15.89), obesity (OR: 8.22, 95% CI,1.5 - 54.17), malignancy (OR: 6.025, 95% CI, 1.1- 33.00), coronary heart disease (OR: 5.31, 95% CI, 1.28 - 21.98) , and C-reactive protein >10 mg/L (OR 4.603, 95% CI, 2.03 - 10.44).Conclusions: Obesity and the presence of malignancy, chronic kidney disease, heart disease and age >60 yearsold are the strongest predictors of mortality in people with COVID-19, despite high CRP results.
Analysis of Risk Management Cycle on Capitation Mechanism at First Level Healthcare Facilities in East Java Rachmad Suhanda; Usman Hadi; Widodo J. Pudjirahardjo; Djazuly Chalidyanto
Indian Journal of Forensic Medicine & Toxicology Vol. 15 No. 2 (2021): Indian Journal of Forensic Medicine & Toxicology
Publisher : Institute of Medico-legal Publications Pvt Ltd

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.37506/ijfmt.v15i2.14381

Abstract

The implementation of risk management is an essential function in an organization to control risk. Basedon the preliminary research that has been carried out, only 4.2% of FLHF in East Java implemented thecomplete risk management process, starting from establishing context to evaluating risks. Modificationsof risk management cycle implementation are made by reviewing the opinion of Carroll (2001) and ISO31000:2009. This research aims to analyze the influence between the stages of implementing modified riskmanagement based at 95 FLHF in East Java. The results show that each stage of the capitation mechanismrisk management has a strong significant influence on each other. The results provide recommendation thatFLHF should improve the understanding and awareness of the risks and expected to be able to apply riskmanagement cycle as a whole.
Co-Authors Ade Rochaeni Agung Dwi Laksono Agung Dwi Wahyu Widodo Agus Santosa Agus Santosa Agustinus Vincent Anggoro DB Sachro Arfijanto, Muhammad V. Arfijanto, Vitanata Aryati , Aryati Aryati Aryati Aryati Aryati Aryati Aryati Aryati Aryati Asmarawati, Tri Pudy Baehaqi Benediktus Yohan Benediktus Yohan Bramanton Bramantono Bramantono, Bramantono Brian Eka Rahman Dicky Febrianto Didik Hasmono Djazuly Chalidyanto Eddy Soewandojo Eko Budi Koendhori, Eko Budi Erika Marfiani Erni J. Nelwan Erni J. Nelwan, Erni J. Erni Juwita Nelwan, Erni Juwita Erwin Astha Triyono Fendy Suhariadi Florentina Sustini Gondo Mastutik Hardiono Hardiono, Hardiono Hari Paraton Haryo N. Yahya Helmia Farida Hening Laswati Putra Herawati Y Heru Suswojo Hidajat, Boerhan Insani Budiningsih Iqhrammullah, Muhammad Isidro Lumanpauw Ismi Masyithah Jaap M. Middeldorp Jeine Stela Akualing Juanita, Lydia Kuntaman Kuntaman Kuntaman Kuntaman Laila Hayati, Laila Lestari, Evi Noerista M Vitanata M.M. Hapsari Ma'rifah, Nurul Margalin, Brilliant Margyaningsih, Nur Ita Marinda Dwi Puspitarini Mariyatul Qiptiyah, Mariyatul Mei Wulan, Sri Mardjiati Monique Keuter Muchlis AU Sofro Muchlis AU. Sofro Muhammad Iqhrammullah Muhammad Miftahussurur Muhammad Vitanata Arfijanto, Muhammad Vitanata Muhammad Vitanata Arifijanto Musofa Rusli Nasronudin Nasronudin Nenci Siagian Nurul Ma'rifah P. Fans P.J,van den Broek Pathak, Yashwant Prihartini Prihartini Purnomo, Windu Puspa Wardhani Puspa Wardhani Puspitarini, Marinda Dwi R. Tedjo Sasmono R. Tedjo Sasmono Rachmad Suhanda Rachman, Brian Eka Ronald Pratama Adiwinoto Sasmono, R. Tedjo Setyarini, Wahyu Sholeh, Mohammad Akbaruddin Sofro, Muchlis AU Sofro, Muchlis AU. Sri Masyeni, Dewa Ayu Putri Sripatmi Sripatmi, Sripatmi Suci Andriani Sugiyatmi, Tri A. Suharto Suharto Susilowati Andajani, Susilowati Tenta Hartian Hendyatama Tripudi Asmarawati Troy Fonda Wahyu Setyarini Widodo J. Pudjirahardjo Widodo Jatim Pudjirahardjo Windu Purnomo Yoes Prijatna Dachlan Yohan, Benediktus