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All Journal Padjadjaran Journal of Dentistry INDONESIAN JOURNAL OF MEDICAL LABORATORY SCIENCE AND TECHNOLOGY
Trinugroho Heri Fadjari, Trinugroho Heri
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Biochemistry, Genetics & Molecular Biology Dentistry Health Professions Immunology & microbiology Medicine & Pharmacology Public Health Social Sciences

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Clinical features of oral cavity of patients with non-Hodgkin’s lymphoma undergoing chemotherapy Suroso, Diptakanya Murdi; Dewi, Tenny Setiani; Fadjari, Trinugroho Heri
Padjadjaran Journal of Dentistry Vol 25, No 2 (2013): July 2013
Publisher : Universitas Padjadjaran

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.24198/pjd.vol25no2.26798

Abstract

Introduction: Non-Hodgkin`s lymphoma is one of hematologic malignancy that responds to chemotherapy. Chemotherapy agent can cause oral complication such as oral mucositis, hemorrhage, xerostomia, hyposalivation and periodontitist. The purpose of this study is to determine the clinical feature of the oral cavity in patients with non-Hodgkin`s lymphoma whose underwent chemotherapy  Method: This study used an observational descriptive method. This type of research is observational descriptive. The study population was non-Hodgkin’s lymphoma sufferers who were undergoing chemotherapy at the Hematology and Medical Oncology Outpatient Installation Division of Internal Medicine at Hasan Sadikin Hospital Bandung. The study sample was taken by consecutive sampling method The numbers of samples in this study were 30 people according to predetermined criteria. Result: The result shows that all samples have abnormalities of the oral cavity that patients who have an abnormality are amounted to 20% and patients who have more than one kind of oral abnormalities amounted to 80%. An abnormality of the oral cavity that the most often found in this study is xerostomia with hyposalivation. Conclusion: Clinical feature of the oral cavity in patients with non-Hodgkin`s lymphoma whose underwent chemotherapy are abnormalities in the oral cavity, where the number of samples that experienced more than one type of oral cavity abnormality was greater when compared to the number of samples with a kind of abnormality. Oral cavity. Most of the samples studied had oral cavity abnormalities in the form of serostomia accompanied by hyposalivation.
Neutrophil-Lymphocyte Ratio (NLR) and Lymphocyte-Monocyte Ratio (LMR) as Covid-19 Screening Parameters Syahrini, Heny; Fadjari, Trinugroho Heri; Dalimoenthe, Nadjwa Zamalek
JURNAL INDONESIA DARI ILMU LABORATORIUM MEDIS DAN TEKNOLOGI Vol 4 No 1 (2022): The future of diagnostic laboratory testing
Publisher : Universitas Nahdlatul Ulama Surabaya

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.33086/ijmlst.v4i1.2281

Abstract

Covid-19 diagnosis generally uses RT-PCR as the gold standard to detect coronavirus-2 (SARS-CoV-2); however, this method requires advanced laboratory equipment. Alternatively, Neutrophil-Lymphocyte Ratio (NLR) and Lymphocyte-Monocyte Ratio (LMR) can be used to identify viral infection. The study aimed: (1) to compare each NLR and LMR ratio in patients with and without COVID-19 and (2) to test the effectiveness of these ratios in identifying COVID-19. The study was conducted at the Haji Adam Malik Central General Hospital by acquiring 87 medical records data. The complete hematologic profile was analyzed from patients with and without COVID-19. The NLR and LMR ratio accuracy were analyzed as a screening tool for COVID-19. The AUC of NLR was 0.638, with cut-off ≤ 2.49, 47.6% sensitivity, and 80% specificity; therefore, the NLR accuracy as a screening for COVID-19 was defined as not good (just sufficient) because of AUC <0,7. The AUC of LMR was 0.661, with cut-off ≥ 3.23, 45.2% sensitivity, and 82.2% specificity; therefore, the LMR accuracy as a screening parameter for COVID-19 is defined as not good (just sufficient) because of AUC <0,7. There were significant differences in hematologic profile in neutrophil, lymphocyte, NLR, LMR between the patients in the COVID-19 group and non-COVID-19 group. NLR and LMR cannot be used as a screening tool because the Area Under Curve (AUC) is not good enough (just sufficient) in detecting COVID-19.
Co-Authors Bachti Alisjahbana Guntur Darmawan Kusumawardhani, R.N. Yasmin Laniyati Hamijoyo, Laniyati Nadjwa Zamalek Dalimoenthe Suroso, Diptakanya Murdi Syahrini, Heny Tenny Setiani Dewi Wijaya, Indra