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Journal : Jurnal Kesehatan

KAJIAN PERESEPAN OBAT OFF-LABEL USIA PADA PASIEN PEDIATRI DI RUMAH SAKIT CAHYA KAWALUYAN PERIODE BULAN JANUARI 2021 Yovita Mercya; Teresa Setyo Ningrum
Jurnal Kesehatan Vol. 9 No. 2 (2021): Oktober : Health Journal “Love That Renewed”
Publisher : Sekolah Tinggi Ilmu Kesehatan Santo Borromeus

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (211.284 KB) | DOI: 10.55912/jks.v9i2.37

Abstract

Obat off-label merupakan obat yang digunakan tidak sesuai dengan informasi resmi obat seperti usia, dosis dan indikasi. Populasi pasien anak sangat berisiko mendapatkan obat off-label karena kurangnya data penelitian. Tujuan penelitian ini adalah untuk mengetahui persentase resep pasien pediatri yang mengandung obat off-label yang menyangkut usia pada usia 0-5 tahun di Klinik Kesehatan Ibu dan Anak Rumah Sakit Cahya Kawaluyan. Penelitian ini merupakan penelitian observasional dengan pendekatan retrospektif menggunakan data farmasi berupa resep dan dibandingkan dengan literatur resmi seperti brosur obat, Pusat Informasi Obat Nasional, British National Formulary for Children kemudian dianalisa secara deskriptif kuantitatif. Sampel dalam peneltian ini adalah resep pasien pediatri usia 0-5 tahun pada bulan Januari 2021. Berdasarkan hasil penelitian diperoleh 2 (0,93%) lembar resep obat off-label usia dari 214 total lembar resep, 2 (0,37%) item obat dari 540 total item obat. Obat off-label usia yang diberikan adalah asam valproat sebagai antiepilepsi dari golongan valproat dan esomeprazole dari golongan penghambat pompa proton untuk pengobatan tukak lambung.
COMPARISON OF LEUCOSITE DECREASE DUE TO THE USE OF FOLFOX AND FOLFIRI CHEMOTHERAPY REGION IN COLORECTAL CANCER PATIENTS AT A PRIVATE HOSPITAL IN BANDUNG, THE PERIOD OF 2021: PERBANDINGAN PENURUNAN LEUKOSIT AKIBAT PENGGUNAAN REGIMEN KEMOTERAPI FOLFOX DAN FOLFIRI PADA PASIEN KANKER KOLOREKTAL SALAH SATU RUMAH SAKIT SWASTA DI BANDUNG PERIODE TAHUN 2021 Yovita Mercya; Lidya Marthan
Jurnal Kesehatan Vol. 10 No. 2 (2022): Oktober: Health Journal "Love That Renews"
Publisher : Sekolah Tinggi Ilmu Kesehatan Santo Borromeus

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Abstract

Colorectal cancer is the third most common type of cancer in the world. Chemotherapy is one of the treatments for colorectal cancer with the most widely used regimens known as FOLFOX and FOLFIRI. One of the most common side effects of chemotherapy from these two regimens is leukopenia. This study aims to examine the characteristics of age, gender, use of the regimen, the decrease in the leukocyte value of each regimen and the difference in the decrease in the leukocyte value from the use of the FOLFOX and FOLFIRI regimens. This research is an observational study, which was carried out retrospectively with total sampling and quantitative descriptive analysis. The data was taken from medical records of colorectal cancer patients who underwent chemotherapy with the FOLFOX and FOLFIRI regimens at one of Bandung Private Hospital for the 2021 period. The results of this study showed that colorectal cancer patients were most dominant at the age of 56-65 years as much as 50% and suffered by mostly male patients as much as 64.3% with the use of both regimens in the same amount, that is 50% each. After undergoing the first chemotherapy, there was a significant decrease in leukocyte values in both regimens. The mean percentage reduction in leukocytes with the use of FOLFOX was 19% and FOLFIRI was 28%, but statistically, the decrease in leukocyte values in the two regimens was not significantly different.
EVALUASI INTERAKSI DAN KETEPATAN PENGATURAN JADWAL OBAT UNIT DOSE DISPENSING PASIEN RAWAT INAP SALAH SATU RUMAH SAKIT DI KOTA BANDUNG PERIODE FEBRUARI 2022: EVALUATION OF INTERACTIONS AND ACCURACY OF ARRANGEMENTS THE UNIT-DOSE DISPENSING DRUG SCHEDULES INPATIENTS IN HOSPITAL AT BANDUNG CITY IN FEBRUARY 2022 Yovita Mercya; Ifvana Pricialiany; Lanang Eko Sampurno Sampurno
Jurnal Kesehatan Vol. 11 No. 2 (2023): Oktober : Health Journal "Love That Renews"
Publisher : Sekolah Tinggi Ilmu Kesehatan Santo Borromeus

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Abstract

Unit Dose Dispensing (UDD) is drug distribution for one dose per patient. UDD can reduce drug interactions because pharmacists monitor it. This study aims to determine the percentage of drug interactions related to scheduling, the severity of interactions, and the most drug interaction pairs. This type of research is observational study conducted retrospectively using purposive sampling of prescriptions and UDD Medication List inpatients at one of hospital in Bandung city in February 2022 and analyzed quantitatively-descriptively. Data processing using drug interaction checker software. Data analyzed based on the incidence of drug interactions, the accuracy of scheduling, the severity, and the most drug interaction pairs. The results were still found drug interactions in 73 patients (43,98%) (n=166) consisting of 194 drug interactions, 113 events (58.25%) the UDD schedule were correct and 81 events (41.75%) were not. Based on the severity level, in all prescriptions with drug interactions, the moderate level was 63.40%, the minor level was 25.26%, and the mayor level was 11.34%. Meanwhile, in 81 events with incorrect schedule, the moderate level was 52 events (64.20%), the minor level was 19 events (23.46%), and the mayor level was ten events (12.35%). The most common interaction was aspirin-clopidogrel with moderate severity.