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All Journal Farmasains : Jurnal Farmasi dan Ilmu Kesehatan Journal of Medicine and Health SELAPARANG: Jurnal Pengabdian Masyarakat Berkemajuan Jurnal Farmamedika (Pharmamedica Journal) Reswara: Jurnal Pengabdian Kepada Masyarakat Jurnal Ekologi, Masyarakat dan Sains Lontara: Journal of Health Science and Technology Jurnal Kesehatan Lontara Journal Of Health Science And Technology Journal of Medicine and Health
Yovita Mercya
Departemen Farmasi, Fakultas Vokasi, Universitas Santo Borromeus, Kabupaten Bandung Barat, 40553
Religion Agriculture, Biological Sciences & Forestry Humanities Biochemistry, Genetics & Molecular Biology Chemical Engineering, Chemistry & Bioengineering Chemistry Computer Science & IT Control & Systems Engineering Economics, Econometrics & Finance Education Electrical & Electronics Engineering Engineering Environmental Science Health Professions Immunology & microbiology Languange, Linguistic, Communication & Media Law, Crime, Criminology & Criminal Justice Medicine & Pharmacology Neuroscience Nursing Public Health Social Sciences Other

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Effect of Mefenamic Acid to Acupuncture Therapy on Carrageenan-Induced Inflammatory Pain in the Hind Limb of Rat Mercya, Yovita; Soemardji, Andreanus A; Fanty, Felesia
Journal of Medicine and Health Vol 1, No 5 (2017)
Publisher : Maranatha Christian University

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Abstract

Nonsteroidal anti-inflammatory drug (NSAID) and acupuncture are treatments forinflammatory pain. The purpose of this study is to see the effectiveness of mefenamic acid, adrug from the class of NSAIDs compared with acupuncture therapy in 24 male Wistar rats thathave received intraplantar induced of carrageenan. The experimental animals are divided intosix groups: pain control group, mefenamic acid group, before-induction acupuncture group,after-induction acupuncture group, before-induction mefenamic acid-acupuncture combinationgroup, and after-induction mefenamic acid-acupuncture combination. Inflammation and painassessment with inflammation volume and pain threshold parameters tenderness is done every60 minutes during 6 hours after induction of carrageenan. The results of animal studies showthat the combination of mefenamic acid - acupuncture before induction (inflammation inhibitionvalue of 40.24%; pain inhibition value 8.95%) shows a significantly smaller value (p <0.05) inreducing inflammation and increasing the pain threshold compared to single mefenamic acidgroup (inflammation inhibition value 58.53%; the pain inhibition value 29.09%) and singleacupuncture therapy before induction (inflammation inhibition value 78.04%; the paininhibition value 23.07%). It happens because mefenamic acid inhibits the action of acupunctureas an analgesic. This study concludes that the administration of mefenamic acid degrades theeffectiveness of acupuncture therapy in addressing inflammatory pain.Keywords: acupuncture, mefenamic acid, carragenaan, analgesic, antiinflammation
Effect of Mefenamic Acid to Acupuncture Therapy on Carrageenan-Induced Inflammatory Pain in the Hind Limb of Rat Mercya, Yovita; Soemardji, Andreanus A; Fanty, Felesia
Journal of Medicine and Health Vol. 1 No. 5 (2017)
Publisher : Universitas Kristen Maranatha

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (593.902 KB) | DOI: 10.28932/jmh.v1i5.538

Abstract

Nonsteroidal anti-inflammatory drug (NSAID) and acupuncture are treatments forinflammatory pain. The purpose of this study is to see the effectiveness of mefenamic acid, adrug from the class of NSAIDs compared with acupuncture therapy in 24 male Wistar rats thathave received intraplantar induced of carrageenan. The experimental animals are divided intosix groups: pain control group, mefenamic acid group, before-induction acupuncture group,after-induction acupuncture group, before-induction mefenamic acid-acupuncture combinationgroup, and after-induction mefenamic acid-acupuncture combination. Inflammation and painassessment with inflammation volume and pain threshold parameters tenderness is done every60 minutes during 6 hours after induction of carrageenan. The results of animal studies showthat the combination of mefenamic acid - acupuncture before induction (inflammation inhibitionvalue of 40.24%; pain inhibition value 8.95%) shows a significantly smaller value (p <0.05) inreducing inflammation and increasing the pain threshold compared to single mefenamic acidgroup (inflammation inhibition value 58.53%; the pain inhibition value 29.09%) and singleacupuncture therapy before induction (inflammation inhibition value 78.04%; the paininhibition value 23.07%). It happens because mefenamic acid inhibits the action of acupunctureas an analgesic. This study concludes that the administration of mefenamic acid degrades theeffectiveness of acupuncture therapy in addressing inflammatory pain.Keywords: acupuncture, mefenamic acid, carragenaan, analgesic, antiinflammation
KAJIAN PERESEPAN OBAT OFF-LABEL USIA PADA PASIEN PEDIATRI DI RUMAH SAKIT CAHYA KAWALUYAN PERIODE BULAN JANUARI 2021 Yovita Mercya; Teresa Setyo Ningrum
Jurnal Kesehatan Vol. 9 No. 2 (2021): Oktober : Health Journal “Love That Renewed”
Publisher : Sekolah Tinggi Ilmu Kesehatan Santo Borromeus

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (211.284 KB) | DOI: 10.55912/jks.v9i2.37

Abstract

Obat off-label merupakan obat yang digunakan tidak sesuai dengan informasi resmi obat seperti usia, dosis dan indikasi. Populasi pasien anak sangat berisiko mendapatkan obat off-label karena kurangnya data penelitian. Tujuan penelitian ini adalah untuk mengetahui persentase resep pasien pediatri yang mengandung obat off-label yang menyangkut usia pada usia 0-5 tahun di Klinik Kesehatan Ibu dan Anak Rumah Sakit Cahya Kawaluyan. Penelitian ini merupakan penelitian observasional dengan pendekatan retrospektif menggunakan data farmasi berupa resep dan dibandingkan dengan literatur resmi seperti brosur obat, Pusat Informasi Obat Nasional, British National Formulary for Children kemudian dianalisa secara deskriptif kuantitatif. Sampel dalam peneltian ini adalah resep pasien pediatri usia 0-5 tahun pada bulan Januari 2021. Berdasarkan hasil penelitian diperoleh 2 (0,93%) lembar resep obat off-label usia dari 214 total lembar resep, 2 (0,37%) item obat dari 540 total item obat. Obat off-label usia yang diberikan adalah asam valproat sebagai antiepilepsi dari golongan valproat dan esomeprazole dari golongan penghambat pompa proton untuk pengobatan tukak lambung.
COMPARISON OF LEUCOSITE DECREASE DUE TO THE USE OF FOLFOX AND FOLFIRI CHEMOTHERAPY REGION IN COLORECTAL CANCER PATIENTS AT A PRIVATE HOSPITAL IN BANDUNG, THE PERIOD OF 2021: PERBANDINGAN PENURUNAN LEUKOSIT AKIBAT PENGGUNAAN REGIMEN KEMOTERAPI FOLFOX DAN FOLFIRI PADA PASIEN KANKER KOLOREKTAL SALAH SATU RUMAH SAKIT SWASTA DI BANDUNG PERIODE TAHUN 2021 Yovita Mercya; Lidya Marthan
Jurnal Kesehatan Vol. 10 No. 2 (2022): Oktober: Health Journal "Love That Renews"
Publisher : Sekolah Tinggi Ilmu Kesehatan Santo Borromeus

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Abstract

Colorectal cancer is the third most common type of cancer in the world. Chemotherapy is one of the treatments for colorectal cancer with the most widely used regimens known as FOLFOX and FOLFIRI. One of the most common side effects of chemotherapy from these two regimens is leukopenia. This study aims to examine the characteristics of age, gender, use of the regimen, the decrease in the leukocyte value of each regimen and the difference in the decrease in the leukocyte value from the use of the FOLFOX and FOLFIRI regimens. This research is an observational study, which was carried out retrospectively with total sampling and quantitative descriptive analysis. The data was taken from medical records of colorectal cancer patients who underwent chemotherapy with the FOLFOX and FOLFIRI regimens at one of Bandung Private Hospital for the 2021 period. The results of this study showed that colorectal cancer patients were most dominant at the age of 56-65 years as much as 50% and suffered by mostly male patients as much as 64.3% with the use of both regimens in the same amount, that is 50% each. After undergoing the first chemotherapy, there was a significant decrease in leukocyte values in both regimens. The mean percentage reduction in leukocytes with the use of FOLFOX was 19% and FOLFIRI was 28%, but statistically, the decrease in leukocyte values in the two regimens was not significantly different.
EVALUASI INTERAKSI DAN KETEPATAN PENGATURAN JADWAL OBAT UNIT DOSE DISPENSING PASIEN RAWAT INAP SALAH SATU RUMAH SAKIT DI KOTA BANDUNG PERIODE FEBRUARI 2022: EVALUATION OF INTERACTIONS AND ACCURACY OF ARRANGEMENTS THE UNIT-DOSE DISPENSING DRUG SCHEDULES INPATIENTS IN HOSPITAL AT BANDUNG CITY IN FEBRUARY 2022 Yovita Mercya; Ifvana Pricialiany; Lanang Eko Sampurno Sampurno
Jurnal Kesehatan Vol. 11 No. 2 (2023): Oktober : Health Journal "Love That Renews"
Publisher : Sekolah Tinggi Ilmu Kesehatan Santo Borromeus

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Abstract

Unit Dose Dispensing (UDD) is drug distribution for one dose per patient. UDD can reduce drug interactions because pharmacists monitor it. This study aims to determine the percentage of drug interactions related to scheduling, the severity of interactions, and the most drug interaction pairs. This type of research is observational study conducted retrospectively using purposive sampling of prescriptions and UDD Medication List inpatients at one of hospital in Bandung city in February 2022 and analyzed quantitatively-descriptively. Data processing using drug interaction checker software. Data analyzed based on the incidence of drug interactions, the accuracy of scheduling, the severity, and the most drug interaction pairs. The results were still found drug interactions in 73 patients (43,98%) (n=166) consisting of 194 drug interactions, 113 events (58.25%) the UDD schedule were correct and 81 events (41.75%) were not. Based on the severity level, in all prescriptions with drug interactions, the moderate level was 63.40%, the minor level was 25.26%, and the mayor level was 11.34%. Meanwhile, in 81 events with incorrect schedule, the moderate level was 52 events (64.20%), the minor level was 19 events (23.46%), and the mayor level was ten events (12.35%). The most common interaction was aspirin-clopidogrel with moderate severity.
Uji Aktivitas Campuran Minyak Kemiri dan Minyak Zaitun terhadap Panjang Rambut Yovita Mercya; Deshinta Ramadani
Lontara Journal of Health Science and Technology Vol 5 No 1 (2024): Ilmu dan Teknologi Kesehatan
Publisher : Lembaga Penelitian dan Pengabdian Masyarakat Politeknik Kesehatan Muhammadiyah Makassar

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.53861/lontarariset.v5i1.433

Abstract

Candlenut oil and olive oil have been discovered to promote hair growth. This experimental study aimed to assess the effectiveness of a combination of candlenut oil and olive oil on the length of hair in male rabbits. The experiment involved two male rabbits, with four areas on their backs shaved to apply the test solution, each area measuring approximately 3 cm x 3 cm and spaced 2 cm apart. Hair samples were collected by shaving six strands of hair from each area on the 3rd, 6th, 9th, 12th, 15th, and 18th days. The treatment groups were divided into a negative control group that received no intervention and test groups that were treated with either candlenut oil alone, olive oil alone, or a combination of candlenut and olive oil. The results of the non-parametric Kruskal-Wallis test revealed a p-value of 0.000 (p ≤ 0.05), indicating a significant difference among the groups. A post hoc test was conducted to determine the group with the best hair length statistically, and it was found that the group receiving candlenut oil had the highest mean rank value, followed by the olive oil group, and then the combination of candlenut and olive oil group.
Sosialisasi Peracikan Sediaan Obat Cair dengan Tablet Pada Tenaga Kefarmasian di Rumah Sakit Cahya Kawaluyan Hesti Purwaningsih; Yovita Mercya; Whisnu Tri Seno Ajie
RESWARA: Jurnal Pengabdian Kepada Masyarakat Vol 5, No 2 (2024)
Publisher : Universitas Dharmawangsa

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.46576/rjpkm.v5i2.4349

Abstract

Peracikan obat merupakan praktik umum dilakukan oleh tenaga kefarmasian di Indonesia, terutama di rumah sakit, untuk menyediakan obat-obatan yang sesuai dengan kebutuhan individu pasien. Salah satu contoh racikan yang sering dilakukan adalah pembuatan sediaan sediaan obat cairdengan penambahantablet. Menurut teori, pembuatan sediaan obat cair dengan zat aktif yang tidak larut dalam air memerlukan penambahan suspending agent agar menghasilkan suatu suspense yang stabil. Namun, penelitian sebelumnya menyatakan bahwa tanpa penambahan suspending agent Na-CMC, sediaan obat cair yang diracik dengan tablet masih memenuhi persyaratan viskositas, sedimentasi, dan redispersibilitas pada hari ke-14. Program ini bertujuan untuk memberikan pemahaman tenaga kefarmasian melalui sosialisasi hasil penelitian mengenai peracikan sediaan obat cairdengan penambahan tablet sehingga akan mengurangi waktu yang diperlukan dalam proses peracikan dengan tetap memberikan pelayanan yang berkualitas. Program ini dilakukan dengan menggunakan metode ceramah dan diikuti 30 tenaga kefarmasian di Rumah Sakit Cahya Kawaluyaan pada 6 Februari 2024. Pada pelaksanaannya, dilakukan pre-test, pemberian materi dan post test. Hasil rata-rata nilai pengetahuan tenaga kefarmasian sebelum dilakukan intervensi sebesar 47,77 dan setelah intervensi menjadi 89,03. Meskipun telah dilakukan pre-test dan post-test untuk mengukur peningkatan pengetahuan, namun tidak secara langsung mempengaruhi kualitas peracikan obat yang dilakukan oleh tenaga kefarmasian. Disarankan untuk melakukan evaluasi terhadap keterampilan praktis dan penerapan pengetahuan dalam program pemberdayaan berikutnya
Uji Aktivitas Campuran Minyak Kemiri dan Minyak Zaitun terhadap Panjang Rambut Yovita Mercya; Deshinta Ramadani
Lontara Journal of Health Science and Technology Vol 5 No 1 (2024): Ilmu dan Teknologi Kesehatan
Publisher : Lembaga Penelitian dan Pengabdian Masyarakat Politeknik Kesehatan Muhammadiyah Makassar

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.53861/lontarariset.v5i1.433

Abstract

Candlenut oil and olive oil have been discovered to promote hair growth. This experimental study aimed to assess the effectiveness of a combination of candlenut oil and olive oil on the length of hair in male rabbits. The experiment involved two male rabbits, with four areas on their backs shaved to apply the test solution, each area measuring approximately 3 cm x 3 cm and spaced 2 cm apart. Hair samples were collected by shaving six strands of hair from each area on the 3rd, 6th, 9th, 12th, 15th, and 18th days. The treatment groups were divided into a negative control group that received no intervention and test groups that were treated with either candlenut oil alone, olive oil alone, or a combination of candlenut and olive oil. The results of the non-parametric Kruskal-Wallis test revealed a p-value of 0.000 (p ≤ 0.05), indicating a significant difference among the groups. A post hoc test was conducted to determine the group with the best hair length statistically, and it was found that the group receiving candlenut oil had the highest mean rank value, followed by the olive oil group, and then the combination of candlenut and olive oil group.
Antidiabetic activity test of infusion combination rosella flower (Hibiscus sabdariffa L.) and cinnamon bark (Cinnamomum burmannii (Nees & T. Nees) Blume) in male mice (Mus musculus) induced by alloxan Chaerul, Rasid; Mercya, Yovita
Farmasains : Jurnal Farmasi dan Ilmu Kesehatan Vol. 9 No. 2 (2024)
Publisher : Universitas Muhammadiyah Malang

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.22219/farmasains.v9i2.36232

Abstract

Diabetes Mellitus (DM) is a disorder of carbohydrate, lipid and protein metabolism which is characterized by increased blood glucose levels. The existence of DM as a public health problem is increasing globally. This experimental research was carried out to determine the activity of a combination of rosella flower infusion and cinnamon bark on blood glucose levels in male mice that had been induced by alloxan. After ensuring that the blood glucose level of the mice was >175 mg/dl, 4 groups were tested, namely test group 1 was given a single rosella flower infusion, test group 2 was given a single cinnamon bark infusion, test group 3 was given a combination of rosella flower infusion and stem bark cinnamon, and the control group were given aqua destillata. Based on the results of the Kruskal-Wallis non-parametric statistical test, it shows a value of p = 0.009 (p £ 0,05), which means there is a difference in the reduction in blood glucose levels between the test groups. Then, to determine the greatest decrease in glucose levels, a Post Hoc test was carried out and the highest mean rank value was obtained (13.00) in the infusion group of the combination of rosella flowers and cinnamon bark, followed by the cinnamon bark infusion group (5.80), and the rosella flower infusion group (5.20).
PROFIL PERESEPAN PENGOBATAN INFEKSI PADA IBU HAMIL DI KLINIK KEBIDANAN DAN KANDUNGAN RUMAH SAKIT CAHYA KAWALUYAN Mercya, Yovita; Tarida Sinaga, Deborah; Anggoro Parulian, Adi
Jurnal Farmamedika (Pharmamedika Journal) Vol 10 No 1 (2025): Jurnal Farmamedika (Pharmamedica Journal)
Publisher : Sekolah Tinggi Teknologi Industri dan Farmasi Bogor

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.47219/ath.v10i1.406

Abstract

During pregnancy, women are more susceptible to infections due to hormonal changes and a weakened immune system. This study aims to determine the characteristics of maternal age, gestational age, gravida, diagnosis, and the profile of anti-infective prescriptions for pregnant women at the Obstetrics and Gynecology Specialist Clinic of Cahya Kawaluyan Hospital. This observational study utilized medical record data of pregnant women receiving outpatient anti-infective treatment during 2023. Using purposive sampling techniques, data were obtained from 44 patients who received anti-infective drugs according to inclusion criteria. The results showed that the majority of pregnant patients were aged 20-35 years (88.6%), with a gestational age of the third trimester (54.5%), and multigravida (56.8%). The most common diagnosis among pregnant women receiving anti-infective treatment was infectious diseases in pregnancy (code O98), accounting for 77.3%, with upper respiratory tract infections being the most frequent (50%). The most commonly used anti-infective drug was cefadroxil, reaching 47.73%, both as a single antibiotic and in combination with other antibiotics. Additionally, ceftriaxone 1 gram injection was often used for prophylaxis before delivery or other complicating conditions. According to the USA-FDA safety category for pregnant women, the most used category of drugs was Category B, accounting for 53.84%.
Co-Authors Adi Anggoro Parulian Ajie, Whisnu Tri Seno Andreanus A Soemardji Andreanus A. Soemardji Angela, Tiara Chaerul, Rasid Decky Gunawan, Decky Deni Mulyana Deshinta Ramadani Felesia Fanty Felesia Fanty Hesti Purwaningsih Ifvana Pricialiany July Ivone Katarina, Yovita Tri Lanang Eko Sampurno Sampurno Lidya Marthan Maharina, Florentina Dian Parulian, Tina Shinta Purwaningsih, Hesti Ramadani, Deshinta Roma Ave Maria Sampurno, Lanang Eko Sinaga, Friska Susanti Niman Tarida Sinaga, Deborah Teresa Setyo Ningrum Wati, Wenny Whisnu Trie Seno Ajie Yura Witsqa Firmansyah