Religious education has so far focused more on cognitive theoretical religious issues, and has paid less attention to transforming cognitive religious knowledge into "meaning" and "values" that need to be internalized by students through various means, media, and forums. 1 As a sign of God's existence, the universe is mentioned in verses that serve as sources of teachings and lessons for humans. The lessons that can be learned from observing the universe are harmony, harmony, and order (Ardi Kumara, 2020). When information that contradicts their beliefs emerges, society is shocked. The information states that humans were created through a process from a clot of blood, then transformed into humans who are then born into the world. In order for humans to learn to seek and develop knowledge by reading, experimenting, observing, investigating, and formulating a theory, everything must be done based on faith. A total of 60 samples from students were predicted to be usable, but only 42 samples could be drawn for data processing of research results, and the analysis of the final report results showed that religious learning in keeping up with the development of technological and information advances in the implementation of Islamic religious learning does not only use memorization and lectures, currently learning activities can use the AI Gemini and Nicemindmap applications. The percentage of difficulties experienced by samples when using the AI Gemini Application in improving the sustainability of Islamic religious learning, the percentage of answers is always 28.57%, the percentage of answers often is 35.71%, the percentage of answers sometimes is 35.71%, the percentage of answers never is 38.09%. Internalization of the values of monotheism towards religion in learning can be implemented with an integrated curriculum (MKWU), integrated learning activities (research & community service) and science integration (Islamization of science), the use of AI Gemini and Nicemindmap. This allows students, particularly those in Informatics Engineering at Unpam, to understand the process and outcomes of Islamic religious education learning using Gemini AI and Nicemindmap, as part of their efforts to internalize the values of monotheism in the application of science.