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Terpenoids from the Stem bark of Aglaia elaeagnoidea and their cytotoxic activity against HeLa and DU145 Cancer Cell lines Dini Oktaviani; Winda Sukmawati; Kindi Farabi; Desi Harneti; Nurlelasari Nurlelasari; Darwati Darwati; Rani Maharani; Tri Mayanti; Agus Safari; Unang Supratman
Molekul Vol 17 No 1 (2022)
Publisher : Universitas Jenderal Soedirman

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.20884/1.jm.2022.17.1.5594

Abstract

Aglaia is the largest genus of the Meliaceae family which contains terpenoid compounds. This type of compounds showed a diverse structures and biological activities that can be found in natural resources. Aglaia elaeagnoidea is a species from Aglaia genus that only has a few previous research. This study was aimed to isolate and determine the chemical structure of terpenoid compounds from the ethyl acetate extract of A. elaeagnoidea stem bark. Ethyl acetate extracts were separated and purified by various chromatographic techniques to obtain compounds 1-5. Compounds 1-5 were identified their chemical structures by spectroscopic methods (IR, MS, and NMR) and comparison with previous reported spectral data. Compounds 1 and 2 were identified as eudesmane-type sesquiterpenoids, 5-epi-eudesm-4(15)-ene-1β,6β-diol (1) and 6α-Hydroxy-eudesm-4(15)-en-1-one (2). Compounds 3-5 were identified as dammarane-type triterpenoids, 20S,24S-epoxy-25-hydroxydammarane-3-one (3), 20S,24S-epoxydammarane-3α,25-diol (4), and 3α-epi-cabraleahydroxy lactone (5). These compounds are first time reported from this plant. Compounds 1-5 were tested for cytotoxicity against HeLa cervical cancer cell and DU145 prostate cancer cell and as a result, compound 4 (20S,24S-epoxydammarane-3α,25-diol) showed the stronger activity compared to other compounds.
Meningkatkan hasil belajar siswa dengan cara multi metode pada materi pada siswa kelas IV SD Negeri Tiris III Kabupaten Probolinggo Uswatun Hasanah; Ribut Prastiwi Sriwijayanti; Nurul Yaqin; Dini Oktaviani; Yuni Wulandari
SEMINAR NASIONAL SOSIAL, SAINS, PENDIDIKAN, HUMANIORA (SENASSDRA) Vol 1 (2022)
Publisher : SEMINAR NASIONAL SOSIAL, SAINS, PENDIDIKAN, HUMANIORA (SENASSDRA)

Show Abstract | Download Original | Original Source | Check in Google Scholar

Abstract

Penelitian ini bertujuan untuk meningkatkan hasil belajar siswa dengan cara multi metode. Dari hasil penelitian yang diperoleh dari uraian sebelumnya agar proses belajar mengajar IPA lebih efektif dan lebih memberikan hasil yang optimal.Dari rata - rata nilai ulangan harian yang diperoleh siswa kelas IV SD Negeri Tiris III hampir setiap siswa mendapatkan nilai rendah pada Materi Pembelajaran Energi dan Penggunaanya.  Penelitian ini adalah Mendeskripsikan penerapan pembelajaran Multi Metode menggunakan contoh sumber energi yang sebenarnya dalam meningkatkan minat dan hasil belajar siswa kelas IV terhadap materi Energi dan Penggunaanya Penelitian dilaksanakan sebanyak dua kali kegiatan yaitu siklus 1 (Senin,  17 Januari 2022) dan siklus II (Senin, 24 Januari  2022). Dilihat dari keberhasilan siswa dal setiap siklus yaitu Jumlah rata-rata tes formatif siklus I (66,16%), dan siklus II (77,91%). Kesimpulan dari penelitian ini adalah pembelajaran Multi Metode dengan menggunakan contoh Sumber energi yang sebenarnya dapat berpengaruh positif terhadap hasil belajar siswa SD Negeri Tiris III, serta pembelajaran ini dapat digunakan sebagai salah satu alternatif pembelajaran IPAditulis
Klasifikasi Tingkat Kepuasan Pelayanan Pembuatan Paspor Menggunakan Algoritma Naïve Bayes Dini Oktaviani; Syarifah Putri Agustini Alkadri; Sucipto Sucipto
JURAL RISET RUMPUN ILMU TEKNIK Vol. 4 No. 1 (2025): April : Jurnal Riset Rumpun Ilmu Teknik
Publisher : Pusat riset dan Inovasi Nasional

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.55606/jurritek.v4i1.4572

Abstract

This research is motivated by the importance of improving the quality of passport making services at the Pontianak City Immigration Office which still faces obstacles such as complicated procedures, limited quotas, lack of officer direction, and mismatches in passport collection schedules that cause public dissatisfaction. This research aims to classify the level of satisfaction of passport making services using the Naïve Bayes algorithm, measure classification accuracy, and develop a website-based system that helps evaluate and improve service quality effectively and efficiently. The method used is a quantitative approach with data collection through questionnaires, interviews, and direct observation of 205 respondents, then the data is processed using the Naïve Bayes algorithm which assumes independence between variables to classify satisfaction levels based on variables such as officer friendliness, officer ability, ease of procedure, and timeliness of service. The main findings show that the Naïve Bayes algorithm is able to classify satisfaction levels with 73% accuracy, 76% precision, 70% recall, and 73% F1-score, signaling the effectiveness of this method in identifying community satisfaction patterns. However, the results also indicate the need for improvement in user interface aspects and system responsiveness so that the system can be widely accepted and provide optimal benefits. The implication of this research is that the application of Naïve Bayes-based data mining methods can be an effective tool in evaluation and decision-making to improve the quality of public services, especially in the field of passport making, and encourage the development of interactive and empirical data-based public service information systems.
COMPARATIVE ANALYSIS OF FINANCIAL PERFORMANCE OF CONVENTIONAL BANK AND SHARIA BANK IN INDONESIA: ANALISIS PERBANDINGAN KINERJA KEUANGAN BANK KONVENSIONAL DENGAN BANK SYARIAH DI INDONESIA Yusriwarti; Boni Kristoven; Dini Oktaviani; M. Ilham Tanjung; Prehasti Regita
MANKEU (JURNAL MANAJEMEN KEUANGAN) Vol. 2 No. 1 (2024): MANKEU (JURNAL MANAJEMEN KEUANGAN)
Publisher : Indragiri Research Center (ingreat)

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.61167/mnk.v2i1.123

Abstract

This research aims to compare the financial performance between Conventional Banks and Sharia Banks in the 2019-2023 period in Indonesia. The samples from this research were BCA Bank as a Conventional Bank and BCA Syariah Bank as a Sharia Bank, and sampling was determined using the purposive sampling method. This research uses financial ratios in the form of Non Performance Financing (NPF), Financing To Deposit Ratio (FDR), Return on Assets (ROA), Operational Expenditure to Operational Income (BOPO), Capital Adequacy Ratio (CAR). This research uses the Independent Sample t-Test. The research results show that Bank BCA has ideal ratio values ​​for ROA, BOPO, CAR, whereas Bank BCA Syariah has ideal ratio values ​​for NPF, FDR and CAR. Overall or the average ratio, there is a significant difference between Conventional Banks and Sharia Banks.