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All Journal Indonesian Journal of Applied Research (IJAR) Riwayat: Educational Journal of History and Humanities
Mustika Weni
Fakultas Kedokteran Universitas Swadaya Gunung Jati
Agriculture, Biological Sciences & Forestry Humanities Biochemistry, Genetics & Molecular Biology Computer Science & IT Education Social Sciences

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Antibacterial Activity Test of Ethanol Extract from Jackfruit Leaves (Artocarpus heterophyllus) on Escherichia coli Bacterial Growth Sri Marfuati*; Mustika Weni
Riwayat: Educational Journal of History and Humanities Vol 6, No 3 (2023): Social, Political, and Economic History
Publisher : Universitas Syiah Kuala

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.24815/jr.v6i3.33578

Abstract

Infectious diseases continues to grow in the health sector due to the colonization of infectious organisms and is the main cause of death worldwide. Infection can be caused by bacteria, fungi, viruses and parasites. One example of bacteria that can cause infection is Escherichia coli. Jackfruit (Artocarpus heterophyllus) have been used by communities for to treat or handle various diseases. This study aims to determine the antibacterial activity from ethanol Jackfruit Leaves against the growth inhibition of the bacterium Escherichia coli using three concentrations of 12,5%, 25% and 50%. Extraction was done by maceration method using ethanol 96%. Antibacterial activity test was performing using the well diffusion method. This results of this study indicate that ethanol extracts of Jackfruit leaves are considered as antibacterial and have antibacterial strength against Escherichia coli at concentrations of 50% include strong groups to inhibit Escherichia coli, while at a concentration of 12,5% and 25% include medium groups to inhibit Escherichia coli.
Antibacterial Activity Test of Ethanol Extract from Jackfruit Leaves (Artocarpus heterophyllus) on Escherichia coli Bacterial Growth Sri Marfuati*; Mustika Weni
Riwayat: Educational Journal of History and Humanities Vol 6, No 3 (2023): Social, Political, and Economic History
Publisher : Universitas Syiah Kuala

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.24815/jr.v6i3.33578

Abstract

Infectious diseases continues to grow in the health sector due to the colonization of infectious organisms and is the main cause of death worldwide. Infection can be caused by bacteria, fungi, viruses and parasites. One example of bacteria that can cause infection is Escherichia coli. Jackfruit (Artocarpus heterophyllus) have been used by communities for to treat or handle various diseases. This study aims to determine the antibacterial activity from ethanol Jackfruit Leaves against the growth inhibition of the bacterium Escherichia coli using three concentrations of 12,5%, 25% and 50%. Extraction was done by maceration method using ethanol 96%. Antibacterial activity test was performing using the well diffusion method. This results of this study indicate that ethanol extracts of Jackfruit leaves are considered as antibacterial and have antibacterial strength against Escherichia coli at concentrations of 50% include strong groups to inhibit Escherichia coli, while at a concentration of 12,5% and 25% include medium groups to inhibit Escherichia coli.
Antioxidant Activity and Tyrosinase Inhibitor of Red Betel Leaf Extract Mustika Weni; Mega Safithri
Indonesian Journal of Applied Research (IJAR) Vol. 4 No. 3 (2023): Indonesian Journal of Applied Research (IJAR)
Publisher : Universitas Djuanda

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.30997/ijar.v4i3.374

Abstract

Red betel leaf (Piper Crocatum) contains flavonoids, tannins, steroids, and alkaloids, known to act as antioxidants. This study aimed to determine the antioxidant activity of red betel leaf extract. The solvents used for the extraction process are ethanol and n-hexane. The thiobarbituric acid (TBA) method was used to determine antioxidant activity. The results showed that the extract of 200 ppm inhibited fatty acid oxidation by 52.13%. No significant difference (α = 0.05) inhibition of unsaturated fatty acids oxidation between the sample and α-tocopherol at 200 ppm. The ethanol extract of red betel can inhibit the tyrosinase enzyme higher than the n-hexane extract of red betel, as seen from the IC50 value of the ethanol extract of red betel of 1655 ppm, while the IC50 value of n-hexane of red betel is 3090.56 ppm.
Co-Authors Mega Safithri Sri Marfuati