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Monika Bhairam, Monika
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Medicine & Pharmacology

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Standardization of herbal medicines – an overview Bhairam, Monika; Roy, Amit; Bahadur, Sanjib; Banafar, Alisha; Turkane, Dhanushram
Journal of Applied Pharmaceutical Research Vol 1 No 1 (2013)
Publisher : Creative Pharma Assent

Show Abstract | Download Original | Original Source | Check in Google Scholar

Abstract

In the few decades, there has been exponentional growth in the field of herbal medicines. Most of the traditional systems of medicine are effective due to lack of standardization. So there is a need to develop a standardization technique. Standardization of herbal formulation is essential in order to assess the quality, purity, safety and efficacy of the drug. There is increasing awareness and general acceptability of the use herbal drugs in today’s medical practice. The world population depends on herbal medicines and product for healthy living. This rise in the use of herbal product has also given rise to various forms of adulteration of the products, which leading to consumers’ and manufacturers’ disappointment and in some instances fatal consequences. The challenge is innumerable and enormous, to fulfill the need of global herbal market. The standardization of this formulations like the organoleptic characters, physical properties, the various physic-chemical properties such as moisture content, ash values, extractive values need to be carried out along with Thin layer chromatography and heavy metal content study should also carried out to ascertain the quality, purity and safety of this herbal formulation.
FORMULATION, OPTIMIZATION AND EVALUATION OF QUICK DISPERSIBLE TABLETS OF SUMATRIPTAN Baghel, Pragya; Roy, Amit; Chandrakar, Shashikant; Bahadur, Sanjib; Bhairam, Monika
Journal of Applied Pharmaceutical Research Vol 7 No 3 (2019)
Publisher : Creative Pharma Assent

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.18231/j.joapr.2019.004

Abstract

The main objective of this study was to prepare Quick Dispersible Tablets of drug Sumatriptan Succinate, which can rapidly disintegrate in the saliva using three different Superdisintegrants that is, Sodium Starch Glycolate, Crospovidone, and Croscarmallose Sodium with Taste Masking Polymer Beta-Cyclodextrin and Aspartame as a Sweetener. The taste masking of the drug was done by mixing it with the polymer beta-cyclodextrin using Solvent Evaporation method and then mixing optimized quantity of aspartame to it. The Quick Dispersible tablets were prepared by Direct Compression Technique using taste masked drug and other formulation excipients. The effect of various Superdisintegrants in three different concentrations has been studied. The prepared tablets were evaluated for wetting time, In-vitro Disintegration time, strength, and in-vitro Dissolution time. As per the results obtained, it was found that the formulation batch no. 4 was found to be the best formulation, as the data?s obtained by it was found to be in the required range of mouth dissolving tablets.
Standardization of herbal medicines – an overview Bhairam, Monika; Roy, Amit; Bahadur, Sanjib; Banafar, Alisha; Turkane, Dhanushram
Journal of Applied Pharmaceutical Research Vol. 1 No. 1 (2013)
Publisher : Creative Pharma Assent

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (214.877 KB)

Abstract

In the few decades, there has been exponentional growth in the field of herbal medicines. Most of the traditional systems of medicine are effective due to lack of standardization. So there is a need to develop a standardization technique. Standardization of herbal formulation is essential in order to assess the quality, purity, safety and efficacy of the drug. There is increasing awareness and general acceptability of the use herbal drugs in today’s medical practice. The world population depends on herbal medicines and product for healthy living. This rise in the use of herbal product has also given rise to various forms of adulteration of the products, which leading to consumers’ and manufacturers’ disappointment and in some instances fatal consequences. The challenge is innumerable and enormous, to fulfill the need of global herbal market. The standardization of this formulations like the organoleptic characters, physical properties, the various physic-chemical properties such as moisture content, ash values, extractive values need to be carried out along with Thin layer chromatography and heavy metal content study should also carried out to ascertain the quality, purity and safety of this herbal formulation.
Formulation, optimization and evaluation of quick dispersible tablets of sumatriptan Baghel, Pragya; Roy, Amit; Chandrakar, Shashikant; Bahadur, Sanjib; Bhairam, Monika
Journal of Applied Pharmaceutical Research Vol. 7 No. 3 (2019)
Publisher : Creative Pharma Assent

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (516.132 KB) | DOI: 10.18231/j.joapr.2019.004

Abstract

The main objective of this study was to prepare quick dispersible tablets of drug sumatriptan succinate, which can rapidly disintegrate in the saliva using three different superdisintegrants that is, sodium starch glycolate, crospovidone, and croscarmallose sodium with taste masking polymer beta-cyclodextrin and aspartame as a sweetener. The taste masking of the drug was done by mixing it with the polymer beta-cyclodextrin using solvent evaporation method and then mixing optimized quantity of aspartame to it. The quick dispersible tablets were prepared by direct compression technique using taste masked drug and other formulation excipients. The effect of various super disintegrants in three different concentrations has been studied. The prepared tablets were evaluated for wetting time, in-vitro disintegration time, strength, and in-vitro dissolution time. As per the results obtained, it was found that the formulation batch no. 4 was found to be the best formulation, as the data’s obtained by it was found to be in the required range of mouth dissolving tablets.
Co-Authors Alisha Banafar, Alisha Amit Roy, Amit Chandrakar, Shashikant Dhanushram Turkane, Dhanushram Pragya Baghel, Pragya Sanjib Bahadur, Sanjib