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All Journal Jurnal Penelitian Pendidikan IPA (JPPIPA)
Asryadin Asryadin
Badan Riset dan Inovasi Daerah Kota Bima
Agriculture, Biological Sciences & Forestry Biochemistry, Genetics & Molecular Biology Chemical Engineering, Chemistry & Bioengineering Chemistry Education Materials Science & Nanotechnology Physics

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Non-Burning Bricks with Natural Materials Environmentally Friendly Adhi Aqwam; Asryadin Asryadin; Muhammad Ichwanul Muslimin; Rizka Khairunnisa; Hetti Koes Endang; Rosita Rosita; Fahrul Annas; Hasan Hasan; Muhammad Rahadian
Jurnal Penelitian Pendidikan IPA Vol 9 No 7 (2023): July
Publisher : Postgraduate, University of Mataram

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.29303/jppipa.v9i7.4718

Abstract

The city of Bima is an area that produces quite a lot of bricks with favorable natural conditions, most of the area consists of rice fields and has a soil texture suitable for making bricks. Red brick is the most widely produced type of brick with a total of 20,000 bricks per month and its use has a negative impact on the environment because it produces carbon dioxide (CO2) emissions which pollute the air and contribute to the greenhouse effect which causes global warming, also as a result of burning bricks. . Based on this, researchers are trying to conduct research related to building materials in Bima City in the form of brick innovations with more environmentally friendly basic materials. The research was carried out using a true experiment and cross sectional approach using conventional bricks as a standard for quality comparison. Descriptive analysis was chosen as the method of analysis in this study. From the results of brick quality tests, all brick formulas met the requirements for water content (<15%), four of the six formulas met the compressive strength requirements based on SNI. The average compressive strength of the four formulas is >5 MPa and meets the Indonesian national brick breaking strength standard (SNI-0021-78). The most significant advantage seen from brick products without burning is the lower water content than conventional bricks and is more environmentally friendly because it uses natural materials and is obtained at competitive prices
Development of a Rapid Diagnostic Method for Simultaneous Detection of Streptococcus viridans in Cases of Heart Disease Pestariati Pestariati; Suhariyadi Suhariyadi; Asryadin Asryadin; Nilasari Indah Yuniati
Jurnal Penelitian Pendidikan IPA Vol 11 No 11 (2025): November
Publisher : Postgraduate, University of Mataram

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.29303/jppipa.v11i11.12730

Abstract

Heart disease is a leading cause of death worldwide, with a complex pathophysiology often involving interactions between genetic factors, the environment, and pathogenic microorganisms. Streptococcus viridans is a clinically significant pathogenic bacterium associated with infections of the cardiovascular system, including infective endocarditis, pericarditis, and other complications. However, timely and accurate diagnosis of this bacterial infection in cases of acute heart disease is often challenging, requiring rapid and sensitive diagnostic methods. Currently, diagnostic methods for detecting Streptococcus viridans in cases of acute heart disease tend to be time-consuming; therefore, developing a rapid diagnostic method that can detect both bacteria simultaneously is crucial. The aim of this study is to develop a rapid and sensitive diagnostic method for detecting the presence of Streptococcus viridans in samples from patients with heart disease. The method used is the identification of specific genes, the design of primer sequences, and the design of probes using specific 16s rRNA genes using bioinformatics techniques. Based on the research results obtained primer pair sequences are: oligonucleotide primer forward 5’-GCGACGATACATAGCCGAC-3’; primer reverse is 3’- CGAGCCAGTCTGAAAGC-5’, while the probe sequence is 5’-GACTGAGACACGGCCCAGACTC-3’. Primer and probe pair quality tests showed very good primer and probe quality for amplification with a 120 bp amplification product. Suggestions in the research are that it is necessary to continue with qPCR optimization to determine the melting temperature which is then carried out sensitivity tests of primer pair sequences and specific 16s rRNA Streptococcus viridans gene probes.
Dengue Hemorrhagic Fever in Bima City: A Study Asryadin Asryadin; Adhi Aqwam; Rizka Khairunnisa; Hetti Koes Endang; Rosita Rosita; Fahrul Annas; Hasan Hasan
Jurnal Penelitian Pendidikan IPA Vol 9 No 6 (2023): June
Publisher : Postgraduate, University of Mataram

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.29303/jppipa.v9i6.4787

Abstract

Cases of Dengue Hemorrhagic Fever (DHF) in Bima City are of concern because of its widespread spread and the number of sufferers continues to grow. The Municipal Government of Bima, West Nusa Tenggara, has established an Extraordinary Event (KLB) status for DHF. This status was assigned as a response to the high increase in DHF cases over the past two months, namely January and February 2023. Although vector control efforts have been made, DHF cases continue to fluctuate and increase significantly in early 2023. Therefore, researchers have conducted a Quick Response Analysis of DHF cases in Bima City with the aim of providing information about DHF cases and analyzing this information, as well as developing recommendations for alternative solutions in preventing an increase in DHF cases in Bima City. Through the descriptive method, it was found that the incidence of DHF in Bima City tends to increase significantly at the beginning of 2023 compared to the previous two years, with 172 positive cases and 4 of them leading to death as of February 10, 2023. One of the things of concern based on the case analysis is the understanding and attitude of the community regarding environmental sanitation. Meanwhile, solutions that can be recommended are in the form of short, medium, and long term recommendations which can be used as a reference for consideration in establishing regulations to control dengue fever
Resistance To Antiretroviral Therapy In People With HIV Asryadin Asryadin; Nilasari Indah Yuniati; Lalu Addien Faqih Panjenengan; Baiq Trisna Satriana
Jurnal Penelitian Pendidikan IPA Vol 9 No 9 (2023): September
Publisher : Postgraduate, University of Mataram

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.29303/jppipa.v9i9.5283

Abstract

Human Immunodeficiency Virus (HIV) is a virus that damages the immune system, and has RNA genetic material which is converted by the reverse transcriptase enzyme into DNA. This research aims to determine the existence of resistance by identifying mutations related to drug resistance in HIV-1, especially in the genes encoding the PR and RT enzymes which are the targets of ARVs. This research uses the observational method. Research data analysis was carried out in the form of descriptive data analysis of the output of each formula based on the results of HIV measurements. This study contains a series of reviews that focus on the topic and incidence and possibility of HIV drug resistance (ART) in PLHIV/PLWHA. The main and important thing in detecting the possibility of resistance to ARV therapy is by examining the genotype and phenotype. Standardization between laboratories for drug resistance studies through the use of various methods, especially to identify mixed bases that cause estimated resistance mutations. Additionally, sequencing of protease, RT, and/or integrase is used to identify the clinical significance of DRM. There are two genetic mechanisms of NRTI resistance, namely: (1) discriminative mutations that activate RT to differentiate between the dideoxy-NRTI chain terminator and the cell's own dNTP; and (2) unblocking mutations that facilitate phosphorylytic excision of NRTI-triphosphate from viral DNA. Blocking mutations are also referred to as thymidine analogue mutations (TAMs).   ARV resistance can be detected by examining the virus genotype which aims to determine the occurrence of mutations in one of the virus codons compared to ARV-sensitive wild type HIV-1 and by in vitro phenotyping, where this method takes quite a long time and is usually focused on finding a regimen new drug
Co-Authors Adhi Aqwam Baiq Trisna Satriana Fahrul Annas Hasan Hasan Hetti Koes Endang Lalu Addien Faqih Panjenengan Muhammad Ichwanul Muslimin Muhammad Rahadian Nilasari Indah Yuniati Pestariati Pestariati Rizka Khairunnisa Rizka Khairunnisa Rosita Rosita Suhariyadi Suhariyadi Yuniati, Nilasari Indah