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All Journal Jurnal Pengabdian Magister Pendidikan IPA Sasambo Journal of Pharmacy
Adelia Riezka Rahim
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Education Health Professions Medicine & Pharmacology

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Aflatoksin: Aspek kesehatan, metode reduksi dan deteksinya Rosyunita Rosyunita; Setyaning Pawestri; Nurmi Hasbi; Adelia Riezka Rahim
Sasambo Journal of Pharmacy Vol. 4 No. 2 (2023): September
Publisher : Universitas Mataram

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.29303/sjp.v4i2.250

Abstract

Food contaminant aflatoxin is a mycotoxin produced by Aspergillus flavus and A. parasiticus. This article aims to discover the pathophysiological, immunological, pharmacological, toxicity, and reduction and detection methods of aflatoxin. Kinds of literature were obtained from Research Gate, Pubmed, and Science Direct with the primary keyword “aflatoxin”. Pathophysiologically, aflatoxin-contaminated food has been proven to cause necrosis in liver cells, developing into liver cancer. Immunologically, aflatoxin decreases monocyte and dendritic cell phagocytosis, neutrophil cell ATP production, and pro-inflammatory cytokine synthesis. Aflatoxin toxicity is at the LD50 of 12-16 mg/kg b.w, causing death. Pharmacologically, 120-201 µg/kg b.w causes aflatoxicosis, in vivo studies indicated that NovaSil, Sulfarophan, and Monanthotaxis caffra leaf extract may reduce its toxicity. Aflatoxins are highly thermostable; hence, once food has been contaminated, they cannot be destroyed by normal cooking process. The control and reduction should be conducted in post-harvest handling, common physical means practiced are heating, drying, and smoking. Chemically using ozone, 0.5 sodium bisulfate, 1% sodium hydroxide, 5% acetic acid, and prochloraz. Biologically using Flavobacterium aurantiacum B-184, Bacillus velezensis DY3108, and, a consortium of Geobacillus and Tepidimicrobium bacteria. Aflatoxin can be detected using TLC, HPLC, MS, ELISA, and UHPLC-ESI MS/MS. The prevention of aflatoxin occurrence is done through good post-harvest handling, good manufacturing practices, and applying regulations accordingly to ensure food products and feed are at acceptable levels of aflatoxin.
Sosialisasi Keterlibatan Keluarga Untuk Meningkatkan Keterampilan Personal Menstrual Hygiene di Darul Hukumaini, Jonggat Rosyunita; Rahmah Dara Ayunda; Lale Justin Elizar; Nurmi Hasbi; Adelia Riezka Rahim
Jurnal Pengabdian Magister Pendidikan IPA Vol 8 No 2 (2025): April-Juni 2025
Publisher : Universitas Mataram

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.29303/jpmpi.v8i2.10985

Abstract

Adolescence is a transitional period from childhood to adulthood during which physical, psychological, and reproductive changes occur. Menstruation is one of the reproductive changes, and family members or other knowledgeable individuals would ideally support it during this process. This community service activity was designed to educate female students about the role of family in the menstrual process and give them accurate information. This service's method began with a questionnaire, followed by a socialization session led by a speaker, and ended with a discussion. Thirty-two female students, ages sixteen to seventeen, participated in this program. Mothers were chosen by 13, 15, 21, and 13 students, respectively, as the main source of information on menstruation, menstrual hygiene, the use of sanitary pads, and the best source of menstrual education, according to the questionnaire replies. The majority of students reported using disposable sanitary pads. It is anticipated that by improving their knowledge and abilities about menstrual personal hygiene, students would contribute to the development of a healthier generation.
Co-Authors Hasbi, Nurmi - Lale Justin Elizar Rahmah Dara Ayunda Rosyunita Rosyunita Setyaning Pawestri