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All Journal Journal Syifa Sciences and Clinical Research (JSSCR)
Ricky Midi Candra
Jurusan Farmasi, Fakultas Kedokteran, Universitas Tanjungpura, Jl. Prof. Dr. H. Hadari Nawawi, Kota Pontianak 78124, Indonesia
Chemistry Medicine & Pharmacology

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Isolasi Dan Identifikasi Terpenoid Fraksi Heksan Daun Premna serratifolia L. Menggunakan GC-MS Ricky Midi Candra; Isnindar Isnindar; Sri Luliana
Journal Syifa Sciences and Clinical Research Vol 5, No 2 (2023): Volume 5 Edisi 2 2023
Publisher : State University of Gorontalo

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.37311/jsscr.v5i2.15311

Abstract

Buas-buas (Premna serratifolia L.) is a plant that belongs to the Verbenaceae family. Terpenoid compounds that exist in buas-buas plants have bioactivity as medicine. Terpenoid compounds are soluble compounds in n-hexane. The purpose of this study was to isolate and identify the terpenoid compounds contained in the n-hexane fraction of buas-buas leaves using the GC-MS method. The buas-buas leaves were macerated with 96% ethanol solvent and then fractionated using a separating funnel with n-hexane as solvent. The n-hexane fraction of buas-buas leaves was isolated using column chromatography with a gradient mobile phase combination of n-hexane and ethyl acetate, then identified using the GC-MS instrument. The terpenoid compounds found in the n-hexane fraction of buas-buas leaves are estimated to be neophytadiene; 3,7,11,15-tetramethyl-2-hexadecen-1-ol; and 2 hydroxy-4a,5-dimethyl-3-(prop-1-en-2-yl) octahydronaphthalen-1-(2H)-one.
Co-Authors Isnindar Isnindar Luliana, Sri