Journal Syifa Sciences and Clinical Research (JSSCR)
Vol 5, No 2 (2023): Volume 5 Edisi 2 2023

Isolasi Dan Identifikasi Terpenoid Fraksi Heksan Daun Premna serratifolia L. Menggunakan GC-MS

Ricky Midi Candra (Jurusan Farmasi, Fakultas Kedokteran, Universitas Tanjungpura, Jl. Prof. Dr. H. Hadari Nawawi, Kota Pontianak 78124, Indonesia)
Isnindar Isnindar (Jurusan Farmasi, Fakultas Kedokteran, Universitas Tanjungpura, Jl. Prof. Dr. H. Hadari Nawawi, Kota Pontianak 78124, Indonesia)
Sri Luliana (Jurusan Farmasi, Fakultas Kedokteran, Universitas Tanjungpura, Jl. Prof. Dr. H. Hadari Nawawi, Kota Pontianak 78124, Indonesia)



Article Info

Publish Date
09 Sep 2023

Abstract

Buas-buas (Premna serratifolia L.) is a plant that belongs to the Verbenaceae family. Terpenoid compounds that exist in buas-buas plants have bioactivity as medicine. Terpenoid compounds are soluble compounds in n-hexane. The purpose of this study was to isolate and identify the terpenoid compounds contained in the n-hexane fraction of buas-buas leaves using the GC-MS method. The buas-buas leaves were macerated with 96% ethanol solvent and then fractionated using a separating funnel with n-hexane as solvent. The n-hexane fraction of buas-buas leaves was isolated using column chromatography with a gradient mobile phase combination of n-hexane and ethyl acetate, then identified using the GC-MS instrument. The terpenoid compounds found in the n-hexane fraction of buas-buas leaves are estimated to be neophytadiene; 3,7,11,15-tetramethyl-2-hexadecen-1-ol; and 2 hydroxy-4a,5-dimethyl-3-(prop-1-en-2-yl) octahydronaphthalen-1-(2H)-one.

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Journal Info

Abbrev

jsscr

Publisher

Subject

Chemistry Medicine & Pharmacology

Description

Journal Syifa Sciences & Clinical Research (JSSCR) is a national journal intended as a communication forum for scientists from many practitioners who use Pharmacology Development in ...