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All Journal Jurnal Pendidikan Kimia (JPKim) Jurnal Farmasi Indonesia Journal of Research in Pharmacy and Pharmaceutical Sciences
Feronika Evma Rahayu
STIKes Medistra Indonesia
Biochemistry, Genetics & Molecular Biology Chemical Engineering, Chemistry & Bioengineering Chemistry Education Environmental Science Health Professions Immunology & microbiology Medicine & Pharmacology Other

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FORMULATION AND STABILITY TEST OF CREAM FROM JUICE OF BELIMBING WULUH (AVERRHOA BILIMBI l.) Feronika Evma Rahayu; Annysa Ellycornia Silvyana; Lia Warti; Dentri Asih
Journal of Research in Pharmacy and Pharmaceutical Sciences Vol 1 No 2 (2022): Vol.1 No.2 DECEMBER (2022)
Publisher : Pharmacy Program, Faculty of Medicine, UPN Veteran Jakarta

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.33533/jrpps.v1i2.6309

Abstract

Research on cream formulations using starfruit (Averrhoa bilimbi L.) juice has been carried out to determine the effect of sodium lauryl sulfate on the physical stability of cream from starfruit juice. Carambola wealth as an active substance is made in cream with varying concentrations of sodium lauryl sulfate of 1%, 1.5%, 2%, and 2.5%. The evaluation was carried out in the form of organoleptic tests, homogeneity, cream type, pH, viscosity, centrifugation, and freeze-thaw. Data analysis was carried out using statistical tests using ANOVA which has a 95% confidence level (α = 0.05), the test is continued with the Tukey HSD test, and the analysis results show significant differences in each formula. The research results concluded that the higher the concentration of sodium lauryl sulfate as an emulsifying agent, the physical stability of the viscosity of the cream from starfruit juice increased.
Formulation and evaluation of liquid soap preparation of robusta green coffee extract (Coffea canephora) with virgin coconut oil (VCO) base as an antibacterial Staphylococcus aureus Ing Mayfa Br Situmorang; Feronika Evma Rahayu; Opi Dwi Nurhayati
Jurnal Pendidikan Kimia (JPKIM) Vol 15, No 3 (2023): December
Publisher : Pascasarjana Universitas Negeri Medan

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.24114/jpkim.v15i3.50078

Abstract

Staphylococcus aureus can be found on the surface of the skin. One way to prevent Staphylococcus aureus on the skin is to clean the skin with soap. Liquid soap effectively removes dirt from the skin surface and protects the skin from bacteria. Determining the robusta green coffee bean extracts (Coffea canephora) appropriate activity was the study’s major aim in a liquid soap that complies with SNI 06-4085-1996 for use as an antibacterial agent and meets the physical quality requirements for liquid soap preparations. The extraction is performed by a soxhlet extraction method with 96% ethanol. The results of the organoleptic test show a difference in color at each concentration, with the concentration of the extract, which is higher, affecting the color and odor, the results of the homogeneity show results that are homogeneous and free of coarse grains, the results of the pH test show results that meet the requirements, namely in the interval 8-11, the results of the viscosity show results that meet the SNI requirements of 400-4000Cps, the results of the foam height test show stable results and meet the SNI requirements of 13-220 mm. the results of the inhibition zone in the liquid bath soap preparation of robusta green coffee bean extract using the disk diffusion method show that F0 = 4.51mm (resistant), F1 = 11.11mm (resistant), F2 = 13.35mm (intermediate) and F3 = 20.57mm (suspicious).Keywords: Coffea canephora; Disc diffusion; Liquid soap; Staphylococcus aureus
Analisis Flavonoid Total dan Aktivitas Antioksidan Fraksi Etanol Kulit Semangka (Citrullus lanatus) Feronika Evma Rahayu; Dede Irma Hidayat; Tunas Alam
Jurnal Farmasi Indonesia Vol 21 No 2 (2024): Jurnal Farmasi Indonesia
Publisher : Fakultas Farmasi Universitas Setia Budi

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.31001/jfi.v21i2.1888

Abstract

Antioxidants are required to keep the body's defenses against free radicals intact. Watermelon rind (Citrullus lanatus (Thunb). & Nakai) contains phenolic compounds which are included in the flavonoid group and can act as natural antioxidant compounds. This study evaluated watermelon rind (Citrullus lanatus (Thunb). & Nakai) for its antioxidant activity. The dried watermelon rind (Citrullus lanatus (Thunb). & Nakai) was extracted using the maceration method and then partitioned into polar (water), non-polar (n-hexane), and semi-polar (ethyl acetate) fractions. Following extraction, the study's methodology is briefly outlined in the second paragraph and is in line with the findings of this publication. The highest total flavonoid value was found in the watermelon rind (Citrullus lanatus (Thunb). & Nakai) ethanol extract, which measured 49.6 mg/g in the ethyl acetate fraction, 48.6 mg/g in the water fraction, and12.05 mg/g in the n-hexane fraction. The ethyl acetate fraction has strong antioxidant activity (55.36), followed by the water fraction (71.25), and the n-hexane is not strong (225.59).
Perbandingan Aktivitas Antioksidan pada Ekstrak Murni, Granul dan Tablet Effervescent Ekstrak Kulit Manggis (Garcinia mangostana L.) Feronika Evma Rahayu; Fenny Sandriyani; Aluwi Nirwana Sani
Jurnal Farmasi Indonesia Vol 21 No 2 (2024): Jurnal Farmasi Indonesia
Publisher : Fakultas Farmasi Universitas Setia Budi

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.31001/jfi.v21i2.2497

Abstract

The mangosteen rind (Garcinia mangostana L.) contains alkaloids, flavonoids, triterpenoids, tannins, and polyphenols. Flavonoids are secondary metabolites found in it which act as antioxidants. Research on antioxidant activity testing with samples of pure extract, effervescent granules, and effervescent tablets from mangosteen rind extract was conducted to determine the antioxidant content in each formulation. The extraction method used in the study was maceration with 96% ethanol solvent followed by rotary evaporation and water bath at 40°C to obtain a concentrated extract. The yield of the extract was 23.4%, meeting the criteria for a good extract. The concentrated extract was then dried in an oven at 40°C to obtain dry extract. Subsequently, phytochemical screening of the mangosteen rind extract was performed to identify the secondary metabolites present. Antioxidant activity testing was conducted using the DPPH method with methanol as the solvent and quercetin as the positive control. The strongest IC50 value was found in the pure mangosteen rind extract with a value of 0.037 ppm, followed by the effervescent granules with an IC50 value of 0.607 ppm, and the effervescent tablets with an IC50 value of 2.517 ppm. A smaller IC50 value indicates a higher antioxidant capacity in scavenging free radicals.
Co-Authors Aluwi Nirwana Sani Annysa Ellycornia Silvyana Dede Irma Hidayat Dentri Asih Fenny Sandriyani Ing Mayfa Br Situmorang Lia Warti Opi Dwi Nurhayati Tunas Alam