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All Journal Jurnal Penelitian Pendidikan IPA (JPPIPA) GHIDZA: Jurnal Gizi dan Kesehatan Multiverse: Open Multidisciplinary Journal
Gusbakti Rusip
Universitas Prima Indonesia
Religion Agriculture, Biological Sciences & Forestry Arts Humanities Biochemistry, Genetics & Molecular Biology Chemical Engineering, Chemistry & Bioengineering Chemistry Earth & Planetary Sciences Economics, Econometrics & Finance Education Energy Engineering Environmental Science Languange, Linguistic, Communication & Media Law, Crime, Criminology & Criminal Justice Library & Information Science Materials Science & Nanotechnology Medicine & Pharmacology Nursing Physics Public Health

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Analisis Uji Beda Gaya Hidup Mahasiswa Urban dan Rural Terhadap Perubahan Perilaku di Fakultas Kedokteran Universitas Prima Indonesia Zahrah Fadhilla Nasution; Gusbakti Rusip; Fiska Maya Wardhani
Multiverse: Open Multidisciplinary Journal Vol. 2 No. 2 (2023)
Publisher : Medan Resource Center

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.57251/multiverse.v2i2.1097

Abstract

This research aims to examine the influence of urban and rural backgrounds on the lifestyle choices and behavioral changes among medical students. The study addresses the question of how different backgrounds shape the students' lifestyles and behavioral patterns. A quantitative approach was employed, involving a sample of 100 medical students (50 from urban areas and 50 from rural areas). Data were collected through a questionnaire and analyzed using a t-test to compare the differences between the two groups. The findings indicate significant variations in lifestyle choices and behavioral changes between urban and rural medical students, with rural students exhibiting higher levels of consumerism and more pronounced behavioral shifts. The study concludes that the students' urban or rural backgrounds play a crucial role in shaping their lifestyles and behaviors, emphasizing the need for contextual considerations in educational interventions and support systems.
Effectiveness of Acemannan Hydrogel Administration at Concentrations of 25%, 50%, 75% Against Decrease in the Number of Macrophages in Periodontitis Rats with Diabetes Mellitus Chandra Susanto; Susanna Halim; Gusbakti Rusip; Nada Aurelia
Jurnal Penelitian Pendidikan IPA Vol 10 No 4 (2024): April
Publisher : Postgraduate, University of Mataram

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.29303/jppipa.v10i4.7077

Abstract

Acemannan activity as a natural polysaccharide from Aloevera has good biodegradability and biocompatibility and has an effect on cell tissue repair. The study's objective was to ascertain whether giving Hydrogel Acemannan at concentrations of 25%, 50%, and 75% would be beneficial in lowering the quantity of macrophages in diabetic periodontitis mice . 48 white Wistar rats were used as research samples, and they were split into four groups at two different observation intervals (days 3 and 7).One-way ANOVA and posthoc LSD statistical tests were used to assess the data. The number of macrophages in each group decreased on day 7 to 3.50 ± 0.354; 2.79±0.431; 1.54 ± 0.292; 0.54 ± 0.292. The results of the one-way ANOVAX test (p≤0.05) showed that the Hydrogel Acemannan concentrations of 25%, 50%, and 75% were effective in reducing the number of macrophages in periodontitis mice with diabetes mellitus. The results of the LSD posthoc test showed that Hydrogel Acemannan concentrations of 25%, 50%, and 75% were substantially more effective than the positive control in reducing the number of macrophages in periodontal mice with diabetes mellitus (p≤0.05).
Peran Selenium dan Vitamin C sebagai Antioksidan dalam Mengatasi Sepsis Akibat Infeksi Bakteri Escherichia Coli : Systematic Literature Review Olivia Des Vinca Albahana Napitupulu; Gusbakti Rusip; Maya Sari Mutia
Ghidza: Jurnal Gizi dan Kesehatan Vol. 9 No. 1 (2025): June
Publisher : Universitas Tadulako

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.22487/ghidza.v9i1.2034

Abstract

Sepsis merupakan respons sistemik yang berbahaya akibat infeksi bakteri, termasuk Escherichia coli, yang dapat menyebabkan kegagalan organ dan kematian. Stres oksidatif dan inflamasi merupakan dua faktor kunci dalam patogenesis sepsis. Penelitian ini bertujuan untuk mengevaluasi peran selenium dan vitamin C sebagai antioksidan dalam menangani sepsis akibat infeksi E. coli. Studi ini merupakan tinjauan literatur sistematis terhadap 10 artikel yang dipublikasikan antara tahun 2015–2024, dengan pendekatan eksperimen hewan, eksperimental klinis, dan kajian literatur. Data dianalisis berdasarkan tahun, metode penelitian, serta efek biologis yang dilaporkan. Selenium berkontribusi dalam meningkatkan aktivitas enzim glutathione peroxidase, menurunkan stres oksidatif, serta melindungi ginjal dari kerusakan. Vitamin C meningkatkan mikrosirkulasi, memperbaiki fungsi imun, dan berperan sebagai antioksidan protektif selama sepsis. Selenium dan vitamin C menunjukkan potensi besar sebagai terapi adjuvan dalam mengatasi sepsis akibat infeksi E. coli. Hasil kajian ini dapat menjadi dasar untuk pengembangan strategi terapi suportif berbasis antioksidan dalam praktik klinis.
Co-Authors Chandra Susanto Fiska Maya Wardhani Maya Sari Mutia Nada Aurelia Olivia Des Vinca Albahana Napitupulu Susanna Halim Zahrah Fadhilla Nasution