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All Journal BioEksakta : Jurnal Ilmiah Biologi Unsoed Bioscientist : Jurnal Ilmiah Biologi Asian Journal of Health and Applied Sciences Proceeding of International Conference on Biology Education, Natural Science, and Technology
Wicaksono, M. Galih
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Agriculture, Biological Sciences & Forestry Biochemistry, Genetics & Molecular Biology Chemistry Education Immunology & microbiology Medicine & Pharmacology Nursing Physics Public Health Social Sciences Veterinary

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Potential Bromelain Pinneapple Extract to Breaker Tempe Protein As Organic MSG Tias, Eriza Putri Ayu Ning; Wicaksono, M. Galih; Hayati, Lu'lu'ul Rosyiqul; Salsabila, Aulia Firda; Prabowo, Kus Alan Dhimas; Setyaningsih, Endang
Asian Journal of Health and Applied Sciences Vol. 1 No. 3 (2022): Asian Journal of Health and Applied Sciences (AJHAS)
Publisher : Lighthouse Publishing

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.53402/ajhas.v1i3.182

Abstract

New alternatives are needed to change flavorings from chemicals to organic so that they do not have a bad impact on health. The study's results proved that giving MSG at a dose of 9 g / day to red blood cells caused the appearance of a micronucleus so that it indicated a mutagenic MSG. The potential of bromelin enzyme contained in pineapple fruit is able to break down proteins from tempe so that it can give rise to a savory taste that is generally found from other flavorings. The purpose of this study was to determine the potential of bromelin extract pineapple, which is a tempe protein breaker as an organic flavoring sourced from various literatures. The research was conducted using a literature review method of reference sources such as google scholar and research gate. A total of 40 articles were found and then selected based on predetermined parameters resulting in 25 selected articles. From the results of the literature search obtained a percentage of 80% for the sampling method on the extraction method, 16% centrifuged and the method using extraction and centrifugation 4%. Meanwhile, judging from the variables studied, 52% were obtained regarding the activity of hydrolyzing proteins, 12% for the characterization of the enzyme bromelin, 8% for the mechanism of action of bromelin as an anti-bacterial and 4% in the stacking of meat, catalyzing peptide bonds, mobilization of bromelin enzymes, meat quality, decreased glucose levels, healing of lukan and physical quality of cheese curd. And when viewed from the part of the pineapple plant that is utilized 44% of the flesh of the pineapple fruit, 12% of the pineapple weevil, 8% each of the flesh of the fruit and the fruit weevil of the fruit, the skin of the pineapple fruit and the flesh of the young pineapple fruit and 4% each of the ripe pineapple weevil, the flesh of the ripe fruit, the stem and the final leaf of the pineapple plant. And when viewed from the use of the benefits of bromelin, a score of 36% was obtained to increase protein levels in the product, 20% to speed up the hydrolysis process, 12% to stack meat, 8% to inhibit streptococcus bacteria, and 4% each was used to hydrolyze collagen. Helps the fermentation process, anti-browning agents fund therapeutic genes.
Nafsu Makan Tikus Putih (Rattus norvegicus) Bunting Yang Mengkonsumsi MSG Organik dan Sintetis Aryanti, Firma; Setyaningsih, Endang; Febriyanti, Amalia; Sagita, Ninit Putry; Putri Febrianti, Ulya Ananda; Nur Fauziah, Daniar Eka; Tias, Eriza Putri Ayu Ning; Wicaksono, M. Galih
BioEksakta : Jurnal Ilmiah Biologi Unsoed Vol 7 No 1 (2025): BioEksakta
Publisher : Fakultas Biologi Universitas Jenderal Soedirman

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.20884/1.bioe.2025.7.1.13633

Abstract

Penelitian ini bertujuan untuk mengetahui pengaruh konsumsi MSG organik dan MSG sintetis terhadap nafsu makan tikus putih (Rattus norvegicus) strain wistar bunting. Penelitian ini didasari oleh tingginya prevalensi stunting di Indonesia, yang dikaitkan dengan pola makan yang tidak sehat. Penelitian ini menggunakan desain eksperimen true eksperimental dengan Rancangan Acak Lengkap (RAL) dan postest only control design. Tikus dibagi menjadi lima kelompok: kelompok kontrol (pakan normal), kelompok MSG organik 60 mg/kgBB, kelompok MSG organik 120 mg/kgBB, kelompok MSG sintetis 60 mg/kgBB, dan kelompok MSG sintetis 120 mg/kgBB. Data nafsu makan dianalisis menggunakan One Way Analysis of Variance (ANOVA) dan uji DMRT. Hasil penelitian menunjukkan bahwa kelompok perlakuan MSG organik dan MSG sintetis memiliki rata-rata nafsu makan yang berbeda secara signifikan. Kelompok MSG sintetis dengan dosis 60 mg/kgBB memiliki nafsu makan tertinggi, diikuti oleh kelompok MSG organic 120 mg/kgBB, kelompok kontrol, kelompok MSG sintetis 60 mg/kgBB, dan kelompok MSG sintetis 120 mg/kgBB. Penelit ian ini menunjukkan bahwa konsumsi MSG organic dapat meningkatkan nafsu makan pada tikus putih strain wistar bunting. Penelitian lebih lanjut diperlukan untuk mengkaji efek jangka panjang konsumsi MSG organik dan MSG sintetis terhadap kesehatan tikus, serta untuk mengkaji potensi MSG organik sebagai alternatif penyedap makanan yang lebih aman.
Gambaran Histologi Ginjal Tikus Putih (Rattus norvegicus) Bunting yang Mengkonsumsi MSG Organik dan MSG Sintetis Fauziah, Daniar Eka Nur; Setyaningsih, Endang; Aryanti, Firma; Sagita, Ninit Pputry; Febrianti, Ulya Ananda Putri; Febriyanti, Amalia; Tias, Eriza putri Ayu Ning; Wicaksono, M. Galih
BioEksakta : Jurnal Ilmiah Biologi Unsoed Vol 7 No 1 (2025): BioEksakta
Publisher : Fakultas Biologi Universitas Jenderal Soedirman

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.20884/1.bioe.2025.7.1.13968

Abstract

Perkembangan globalisasi memberikan dampak pada pola konsumsi masyarakat Indonesia, Monosodium Glutamat (MSG) atau sering disebut vetsin merupakan bahan tambahan pada masakan yang sudah tidak asing lagi. Penggunaan MSG yang melebihi takaran dan dalam waktu panjang memiliki dampak bagi kesehatan salah satunya yaitu organ ginjal, yang fungsi utama ginjal yaitu menyaring darah dan mengeluarkan sisa metabolisme dari dalam tubuh. MSG berbahan dasar organik dapat menjadi alternatif penggunaan MSG sintetis. Penelitian ini termasuk penelitian deskriptif kuantitatif, menggunakan Rancangan Acak Lengkap (RAL), yang bertujuan untuk mengetahui gambaran histologi ginjal tikus putih (Rattus norvegicus) Strain Wistar bunting yang mengkonsumsi MSG organik dan MSG sintetis. Hasil yang didapatkan terdapat perbedaan kerusakan nekrosis sel yang bermakna antara pemberian MSG organik dan MSG sintetis yaitu dengan nilai probabilitas (sig.) adalah 0.002 < 0.05 pada kelompok kontrol dan kelompok perlakuan. Namun, pada kerusakan berupa hemoragi, diameter glomerulus, dan lebar ruang bowman tidak terdapat perbedaan kerusakan yang bermakna antara pemberian MSG organik dan MSG sintetis pada kelompok kontrol dan kelompok perlakuan.
Kadar Protein Plasma Darah Tikus Putih (Rattus norvegicus) Bunting yang Mengkonsumsi MSG Organik dan MSG Sintetis Sagita, Ninit Putry; Setyaningsih, Endang; Febrianti, Ulya Ananda Putri; Fauziah, Daniar Eka Nur; Febriyanti, Amalia; Ariyanti, Firma; Tyas, Eriza Putri Ayu Ning; Wicaksono, M. Galih
Bioscientist : Jurnal Ilmiah Biologi Vol. 13 No. 1 (2025): March
Publisher : Department of Biology Education, FSTT, Mandalika University of Education, Indonesia.

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.33394/bioscientist.v13i1.13457

Abstract

This study aims to determine the levels of blood plasma protein in pregnant white rats (Rattus nervagicus) that consume Organic MSG and Synthetic MSG. This research method is experimental using a Completely Randomized Design (CRD) by random sampling 21 pregnant white rats with 3 replications and 7 treatments consisting of positive control treatments, P1 = 0.5 ml Organic MSG, P2 = 1 ml Organic MSG, P3 = 2 ml Organic MSG, P4 = 0.5 ml Synthetic MSG, P5 = 1 ml Synthetic MSG, P6 = 2 ml Synthetic MSG for 19 days. The variables measured were blood plasma protein levels measured using a refractometer with units of g / dL. The data tested using SPSS analysis with one way ANNOVA test then continued with Duncan's Multiple Range Test (DMRT). The results showed that Organic MSG had a positive effect on blood plasma protein levels which were significant to the difference in blood plasma protein levels. This can be implied in the health of pregnant rats if there is MSG that enters it will provide viscosity to the blood so that blood plasma protein will be high working hard to produce white blood cells to balance red blood cells that affect immunity. The blood plasma protein levels of pregnant white rats given liquid Organic MSG were the highest at 13.562 g/dL and the lowest at 13.55 g/dL.
Jumlah Eritrosit Tikus Putih (Rattus norvegicus) Strain Wistar Bunting yang Mengonsumsi MSG Organik dan Sintetis Febriyanti, Amalia; Setyaningsih, Endang; Fauziah, Daniar Eka Nur; Aryanti, Firma; Sagita, Ninit Putry; Febrianti, Ulya Ananda Putri; Tias, Eriza Putri Ayu Ning; Wicaksono, M. Galih
Bioscientist : Jurnal Ilmiah Biologi Vol. 13 No. 1 (2025): March
Publisher : Department of Biology Education, FSTT, Mandalika University of Education, Indonesia.

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.33394/bioscientist.v13i1.15109

Abstract

This study aims to determine the number of erythrocytes in pregnant Wistar strain white rats (Rattus norvegicus) consuming organic and synthetic MSG. This study used a Completely Randomized Design (CRD) with 21 samples, 7 treatments, and 3 replications; control treatment (normal feed), P1 (60 mg/kgBW organic MSG), P2 (120 mg/kgBW organic MSG), P3 (240 mg/kgBW organic MSG), P4 (60 mg/kgBW synthetic MSG), P5 (120 mg/kgBW synthetic MSG), and P6 (240 mg/kgBW synthetic MSG). The analysis includes the number of erythrocytes in white rats (Rattus norvegicus), One Way ANOVA test using SPSS version 29, followed by Duncan's Multiple Range Test (DMRT) to determine the mean differences between treatments. The research results show that the number of erythrocytes in the control group (normal) was 6.97 x 106 / µL, P1 (5.17 x 106 / µL), P2 (5.37 x 106 / µL), P3 (5.89 x 106 / µL), P4 (7.61 x 106 / µL), P5 (7.90 x 106 / µL), and P6 (8.29 x 106 / µL). Thus, the administration of organic and synthetic MSG affects the number of erythrocytes in pregnant white rats (Rattus norvegicus) of the Wistar strain, marked by an increase in the number of erythrocytes. The lowest number of erythrocytes was in P1 (60 mg/kgBB), and the highest number of erythrocytes was in P6 (240 mg/kgBB).
Consumer Acceptance of Vegetable Protein and No Preservatives in Organic MSG (Monosodium Glutamate) Prabowo, Kus Alan Dhimas; Tias, Eriza Putri Ayu Ning; Wicaksono, M. Galih; Setyaningsih, Endang
Proceeding of International Conference on Biology Education, Natural Science, and Technology 2024: Proceeding of International Conference on Biology Education, Natural Science, and Technology
Publisher : Universitas Muhammadiyah Surakarta

Show Abstract | Download Original | Original Source | Check in Google Scholar

Abstract

Allergy is a response from the body's defense to reject when exposed to certain antigens. When the antigen (allergen) enters the body's tissue, there are two responses produced by the body, namely the allergen that is successful in destroying it or the allergen that damages the body's tissue. Proteins are polypeptide macromolecules composed of a number of L-amino acids linked by peptide bonds. MSG (Monosodium Glutamate) is a gram of sodium derived from glutamic acid. The aim of this research is to determine consumer acceptance of vegetable protein .This research uses quantitative research methods by distributing questionnaires to the public. As well as helping to provide replacement products to people who are allergic to animal protein. The results of the questionnaire that was given to the public, of the 53 respondents who were given the questionnaire, found that 32 respondents chose to use plant-based products and the remainder chose not to use plant-based products. These plants are allergic to animal protein and the rest do not experience allergies.
Co-Authors Ariyanti, Firma Aryanti, Firma Endang Setyaningsih Fauziah, Daniar Eka Nur Febrianti, Ulya Ananda Putri Febriyanti, Amalia Hayati, Lu'lu'ul Rosyiqul Nur Fauziah, Daniar Eka Prabowo, Kus Alan Dhimas Putri Febrianti, Ulya Ananda Sagita, Ninit Pputry Sagita, Ninit Putry Salsabila, Aulia Firda Tias, Eriza Putri Ayu Ning Tyas, Eriza Putri Ayu Ning