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All Journal Folia Medica Indonesiana Science and Technology Indonesia Indonesian Applied Physics Letters Taqrib : Journal of Islamic Studies and Education
Aminatun
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Religion Humanities Biochemistry, Genetics & Molecular Biology Chemical Engineering, Chemistry & Bioengineering Education Electrical & Electronics Engineering Environmental Science Materials Science & Nanotechnology Physics Social Sciences Other

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INVESTIGATION OF RELIGIOUS MODERATION VALUES IN GROWING TOLERANT BEHAVIOR IN STUDENTS THROUGH THE STORY OF WALISONGO : INVESTIGATION OF RELIGIOUS MODERATION VALUES IN GROWING TOLERANT BEHAVIOR IN STUDENTS THROUGH THE STORY OF WALISONGO Widodo algani; Aminatun
Taqrib : Journal of Islamic Studies and Education Vol. 1 No. 2 (2023): Taqrib : Journal of Islamic Studies and Education
Publisher : CV. Doki Course and Training

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.61994/taqrib.v1i2.155

Abstract

Islam encourages its followers to behave tawasuth, meaning in the middle or balanced, not extreme, and not inclusive. NaturetawasuthThis is part of religious moderation that should be instilled in students so that students have a moderate attitude in the life of the nation and state. In the midst of the plurality of the Indonesian nation, religious moderation is absolutely necessary and taught to the students in order to become human beings who are conciliatory, full of love and tolerant in the future. The involvement of religious teachers in providing an understanding of nature tawasuth for students, it needs to be cultivated and echoed. The content of Islamic religious education material emphasizes understanding compassion, loving each other, respecting each other, and helping each other in goodness. Because with this understanding, students can implement it in students' daily lives. The article discusses the role of religious teachers in instilling religious moderation.
Synthesis of a 3D Porous Multicomponent Bioceramic Scaffold Sari, Yessie Widya; Munir, Ryaas Mishbachul; Saputra, Angga; Sari, Mona; Aminatun; Suciati, Tri; Mohamad, Che Wan Sharifah Robiah; Gunawarman; Yusuf, Yusril
Science and Technology Indonesia Vol. 9 No. 2 (2024): April
Publisher : Research Center of Inorganic Materials and Coordination Complexes, FMIPA Universitas Sriwijaya

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.26554/sti.2024.9.2.235-243

Abstract

In this study, 3D porous multicomponent bioceramic scaffolds were fabricated. Hydroxyapatite (HA) and carbonate-substituted hydroxyapatite (CHA) synthesized from Asian moon scallop shell (Amusium pleuronectes) served as the bioceramics, whereas alginate and chitosan served as the polymeric components. The study was focused on determining whether the presence of polyvinyl alcohol (PVA) in the scaffold exerted an impact. When PVA was not included, the morphological examination revealed that the samples exhibited porous structures characterized by effective pore interconnectivity and a substantial pore size. X-ray diffraction and scanning electron microscopic analyses indicated that the inclusion of PVA led to a decrease in the crystallinity, pore size, and porosity of the scaffolds. Those containing PVA exhibited porosity levels in the range of 56%–60%, and pore sizes ranged from 42 to 90 µm. These properties may provide advantages for the scaffold with respect to the ability for cell migration and cell attachment, thus enhancing new bone formation. Moreover, the compositions of HA and chemically modified HA (CHA) within the scaffold influenced the crystallinity and uniformity of the scaffold morphology. This finding suggests the potential for crafting a customized porous bioceramic scaffold based on specific compositions.
In Vitro Characterization of Poly(Ethylene Glycol) Dimethacrylate-Nanofibrillated Cellulose as an Injectable Biomaterial for Herniated Nucleus Pulposus Substitute Prihartini Widiyanti; Yurituna Firda; Aminatun; Herry Wibowo
Folia Medica Indonesiana Vol. 60 No. 1 (2024): March
Publisher : Universitas Airlangga

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.20473/fmi.v60i1.50084

Abstract

Highlights:1. Novel synthetic biopolymer hydrogels were successfully prepared from pristine poly(ethylene glycol) dimethacrylate (PEGDMA) and nanofibrillated cellulose (NFC) using the photopolymerization method.2. PEGDMA-NFC biocomposite hydrogel can be developed as an affordable biomaterial for herniated nucleus pulposus substitute, with the potential to meet clinical application standards. Abstract Herniated nucleus pulposus develops when the intervertebral disc portudes through the annulus fibrosus due to the rupture of the annulus fibrosus or a decrease in proteoglycans. Hydrogel implant material can be injected into the disc space to restore disc thickness caused by disc degeneration with minimal invasiveness. This study aimed to characterize poly(ethylene glycol) dimethacrylate-nanofibrillated cellulose (PEGDMA-NFC) in vitro as a potential biomaterial for herniated nucleus pulposus substitute. This study utilized PEGDMA-NFC to treat first-degree herniated nucleus pulposus using the photopolymerization method. PEGDMA was selected because of its hydrophilic ability to produce hydrogel. The addition of NFC to the PEGDMA precursor was expected to show mechanical properties as a hydrogel bio composite candidate. The characterization of PEGDMA-NFC was conducted using three tests: Fourier-transform infrared spectroscopy (FTIR), viscosity assessment, and an in vitro injection testing model. The normal distribution of the data was analyzed using the Kolmogorov-Smirnov test, while the homogeneity was assessed using Levene's test. Homogenous and normally distributed data were analyzed using a one-way analysis of variance (ANOVA) with a p-value of <0.05. The explored concentrations of PEGDMA-NFC included a ratio of 1:0 for the control samples and ratios of 1:0.5 (K1), 1:0.75 (K2), and 1:1 (K3) for the experimental samples. The FTIR analysis revealed the presence of various functional groups in PEGDMA-NFC, indicating its potential classification as a hydrogel biomaterial. The characterization data showed that the K3 sample yielded the most favourable outcome with a viscosity value of 74.67 dPa·s. From the in vitro injection testing result, the addition of NFC demonstrated that the hydrogel would not rupture when released from the mold. The hydrogel could be injected with an 18 gauge needle. The statistical analysis results showed a significant difference among the samples (p<0.05). This study concludes that the PEGDMA-NFC hydrogel biocomposite can be effectively applied in herniated nucleus pulposus cases.
The Innovation of 3D Printing Application in The Making of Bone Scaffold as Spinal Tuberculosis Drug Delivery System Wardhani, Inten Firdhausi; Hikmawati, Dyah; Putra, Alfian Pramudita; Aminatun; Parastuti, Frazna
Indonesian Applied Physics Letters Vol. 6 No. 1 (2025): Volume 6 No. 1 – December 2025
Publisher : Universitas Airlangga

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.20473/iapl.v6i1.84057

Abstract

The third highest number of tuberculosis (TB) cases was found in Indonesia. In severe cases, there is a chance for this disease to happen in the spine, which is known as spinal tuberculosis. This study examined an innovation that combined 3D-printed bone scaffolds with an injectable bone substitute (IBS) in paste form. Five pore-size variations of the bone scaffolds (600, 800, 1000, 1200, and 1400) µm were printed using an FDM 3D printer and based on Polylactide Acid (PLA) filaments. Moreover, the IBS paste was produced based on nano-hydroxyapatite (nano-HA), gelatin, hydroxypropyl methylcellulose (HPMC), and streptomycin (TB drug). The FTIR test indicates some functional groups were recorded and identified as typical bonds owned by each constituent material: stretching C-H for PLA, PO43- which represented nano-HA, amine for gelatin, stretching C-OH for HPMC, and ether for streptomycin. Furthermore, various pore-size 3D-printed bone scaffolds were characterized by their porosity, resulting in a range of 55.860% to 68.017%. The result of SEM revealed that the IBS-associated scaffold still had micropores on the surface of the scaffold. These pores let the drug load in the IBS paste release, which could be proven by drug release and the anti-TB test. Moreover, this combined biomaterial was confirmed to be a non-toxic, biodegradable material. The innovation of IBS-associated 3D-printed bone scaffold for future treatment of spinal TB represents a potential breakthrough in the medical field. This technology enables localized and regulated drug delivery, reduces systemic adverse effects, and accelerates recovery. Islam considers health as part of hifdz an-nafs (protection of life), one of the primary objectives of maqasid al-shari’ah (Islamic teachings). This development underlined that such innovations are not only scientifically significant but also carry substantial shari (Islamic legal) legitimacy.
Co-Authors Alfian Pramudita Putra Angga Saputra Gunawarman Herry Wibowo Mohamad, Che Wan Sharifah Robiah Munir, Ryaas Mishbachul Parastuti, Frazna Prihartini Widiyanti Sari, Mona Tri Suciati Wardhani, Inten Firdhausi Widodo algani Yessie Widya Sari Yurituna Firda Yusril Yusuf