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Cholesterol-lowering Effect of Soy Nuts and Tempeh on Hypercholesterolemic Subjects Zulaikha, Hermawati Nur; Dijaya Muliadi, Rendy; Kartawidjajaputra, Felicia; Antono, Lina
Journal Akademik Universitas Swiss German Vol. 4 No. 2 (Feb 2023)
Publisher : Swiss German University & Perhimpunan Penggiat Pangan Fungsional dan Nutrasetikal Indonesia (P3FNI)

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.33555/jffn.v4i2.100

Abstract

Exploration towards food with cholesterol-lowering property would be beneficial to reduce the incidents of cardiovascular caused by increasing number of people with hypercholesterolaemia. As much as 42 participants with total cholesterol (TC) levels ≥4.92 mmol/L were studied in a three-arms parallel intervention trial. As much as 72g soy nuts and 66g tempeh were consumed daily (25g soy protein/day) for six weeks, while control group was not given any sample. TC level and body composition were measured before and after the treatment for all groups. In soy nuts group, lower TC level was observed (-0.85±0.82 mmol/L, p<0.05) compared to the control group. Meanwhile in tempeh group, non-significant lower TC level was also observed (-0.40±1.19 mmol/L). Differences in body composition parameters were also measured and resulted in significant lower body weight, fat, and visceral fat in soy nuts group (p<0.05) while in tempeh group, only body weight and waist circumference were significantly decreased (p<0.05). This study suggested that daily consumption of soy nuts and tempeh containing 25g soy protein for six weeks showed a tendency to lower TC levels in hypercholesterolaemic-Indonesian participants. A more significant effect might be observed in subject with higher TC levels; and thus, further study is encouraged.
Metabolic Diseases Predictor Analysis Based on Single Nucleotide Polymorphisms and Lifestyle Factors: Preliminary Study in Indonesia Subali, Dionysius; Setiawan, James; Kimberly, Patricia; Dijaya, Rendy; Kartawidjajaputra, Felicia; Antono, Lina; Christos, Revelo Eved; Wibisana, Lenny Mulianie; Shih, Yang-Chia
Journal of Health and Nutrition Research Vol. 4 No. 3 (2025)
Publisher : Media Publikasi Cendekia Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.56303/jhnresearch.v4i3.527

Abstract

Type 2 Diabetes Mellitus (T2DM) and cardiovascular disease (CVD) emerged as a cause of high mortality rates in low-middle-income countries, including Indonesia. Understanding predictor variables to the commonly used biomarkers, including lipid profiles and blood glucose levels, can thus be beneficial in disease prevention strategies. To support that, this study aims to analyze the genetic, lifestyle, and disease history variables as predictors towards lipid and blood glucose profiles. The respondent’s data were collected from clinical data, food recall, health history, and genetic profiling. From the results, APOA5 rs662799 is positively correlated with triglyceride (TG) levels. Sugar, fat, fiber, and calorie intake also significantly affect lipid and blood glucose profiles. Exercise conditions such as aerobic and flexibility exercise duration significantly correlated with low-density lipoprotein cholesterol (LDL-C) and high-density lipoprotein cholesterol (HDL-C) profiles. Disease history in individuals and families emerged as additional variables associated with the response variables. These findings can serve as a preliminary study for understanding health predictors that can be used to predict incident of metabolic diseases in the Indonesian population.
The Effect of Energy Gel Administration in Preventing Declining Running Performance of Healthy Recreational Runners Sari, Salsabila Permata; Purba, Patricia Roulina; Oktaviani, Carissa Ramadhania; Muliadi, Rendy Dijaya; Antono, Lina; Kartawidjajaputra, Felicia
Sport and Nutrition Journal Vol. 7 No. 2 (2025)
Publisher : Universitas Negeri Semarang

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.15294/spnj.v7i2.33652

Abstract

A half-marathon is a type of endurance sport that is increasingly popular in Indonesia. During endurance activities, the body experiences a decrease in glycogen reserves and blood glucose levels, which can lead to reduced physical performance and increased fatigue. Energy gels are concentrated sources of carbohydrates to provide fast-absorbing energy during exercise. Consuming energy gels during running is considered beneficial for maintaining performance and preventing fatigue. Most research on energy gel consumption focused on trained athletes; the effect of energy gel consumption for recreational runners, however, is unclear. The objective of this study was to examine the impact of energy gel consumption on maintaining running performance in healthy, recreational Indonesian half-marathon runners. In this crossover study, sixteen recreational runners received energy gel (28 g/serving carbohydrate), konjac jelly (4 g/serving carbohydrate), and mineral water supplementation on three separate occasions during their running. Self-reported performance data (running duration, distance, elevation, rate of perceived exertion, and heart rate) were collected using a web-based questionnaire after each session, and assessed with the Friedman Test and the Wilcoxon Signed Ranks Test. In this study, energy gel consumption significantly reduced the rate of perceived exertion (RPE) compared to mineral water consumption (p < 0.05). However, no significant effect on running duration (p>0.05) nor heart rate (p>0.05) was observed.