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All Journal Jurnal Ilmiah Universitas Batanghari Jambi Qanun Medika - Medical Journal Faculty of Medicine Muhammadiyah Surabaya
Muhammad Alim Jaya
Universitas Muslim Indonesia
Agriculture, Biological Sciences & Forestry Civil Engineering, Building, Construction & Architecture Economics, Econometrics & Finance Education Health Professions Law, Crime, Criminology & Criminal Justice Medicine & Pharmacology

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Ekstrak Daun Bandotan (Ageratum conyzoides lin) Memperbaiki Perilaku Depresi pada Mus Musculus Melanie Ajeng Pratama; Muhammad Alim Jaya; Hanna Aulia Namirah; Ilma Khaerina Amaliyah Bakhtiar; Suci Noviyanah Ansary
Jurnal Ilmiah Universitas Batanghari Jambi Vol 24, No 3 (2024): Oktober
Publisher : Universitas Batanghari Jambi

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.33087/jiubj.v24i3.5556

Abstract

This study aims to assess immobility time in Sham group mice (Mus musculus), assess the effect of fluoxetine antidepressant on immobility time in mice (Mus musculus), assess the impact of bandotan leaf extract antidepressant (Ageratum conyzoides lin) on immobility time in mice (Mus musculus), evaluate the antidepressant effectiveness of the combination of bandotan leaf extract (Ageratum conyzoides lin) with fluoxetine on immobility time in mice (Mus musculus), and compare the efficacy of the four groups, namely group 1 (Sham), group 2 (fluoxetine), group 3 (bandotan leaf extract (Ageratum conyzoides lin)), and group 4 (Fluoxetine with bandotan leaf extract (Ageratum conyzoides lin)). This study uses a type of quantitative approach and pure experimental method (true experimental research) with Posttest only Control Group Design research design. The results showed that the mean immobility time in mice (Mus musculus) group 1 (Sham) was for 34 ± 22.1 seconds. The average immobility time in mice (Mus musculus) group 2 (Fluoxetine) is for 162.5 ± 44.43 seconds. The average immobility time in mice (Mus musculus) group 3 (Bandotan leaf extract) was 172.67 ± 40.5 seconds. The average immobility time in mice (Mus musculus) group 4 (Combination of fluoxetine with bandotan leaf extract) was 118.83 ± 24.1 seconds. The combination of fluoxetine with bandotan leaf extract has significance (p-value 0.039 <0.05) as an antidepressant in reducing immobility time in mice so that bandotan leaves can act as adjuvant therapy.
The Relationship Between Spirituality and Anxiety Levels in Third-Trimester Pregnant Women Syafiq Putra Adiyatma; Nasrudin Andi Mappaware; Susdiaman; Muhammad Alim Jaya; Zulfitriani Murfat
Qanun Medika - Jurnal Kedokteran FK UMSurabaya Vol 10 No 02 (2026): Qanun Medika Vol 10 No 02 July 2026
Publisher : Universitas Muhammadiyah Surabaya

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.30651/jqm.v10i02.31553

Abstract

The third trimester is a phase of pregnancy that is prone to increased anxiety before delivery, and spirituality is thought to play an essential role in helping to reduce this anxiety. This study aims to analyze the relationship between spirituality levels and anxiety levels in pregnant women in the third trimester. This study employed an analytical observational design with a cross-sectional approach and was conducted at RSIA Sitti Khadijah 1, Muhammadiyah Branch, Makassar, from November 10 to December 8, 2025. This study employed a total sampling approach to recruit 31 pregnant women in the third trimester who met the inclusion criteria. Spirituality levels were measured using the Daily Spiritual Experience Scale (DSES), and anxiety levels were measured using the Generalized Anxiety Disorder-7 (GAD-7). The results showed that most respondents had minimal anxiety levels (77.4%) and high spirituality levels (83.9%). The correlation test results showed a significant relationship between spirituality levels and anxiety levels (p = 0.000). This study suggests that higher spirituality is associated with lower anxiety levels. Therefore, it can be concluded that spirituality plays a vital role in helping pregnant women manage anxiety before childbirth and can be considered as part of a holistic approach to antenatal care.
Co-Authors Hanna Aulia Namirah Ilma Khaerina Amaliyah Bakhtiar Melanie Ajeng Pratama Nasrudin Andi Mappaware Suci Noviyanah Ansary Susdiaman Syafiq Putra Adiyatma Zulfitriani Murfat