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All Journal Jurnal Ilmiah Universitas Batanghari Jambi Borneo Journal of Medical Laboratory Technology AVERROUS: Jurnal Kedokteran dan Kesehatan Malikussaleh Jurnal Pengabdian Masyarakat: Humanity and Medicine IPSSJ
Suci Noviyanah Ansary
Departemen Farmakologi, Fakultas Kedokteran, Universitas Muslim Indonesia, Makassar, Indonesia
Agriculture, Biological Sciences & Forestry Biochemistry, Genetics & Molecular Biology Civil Engineering, Building, Construction & Architecture Dentistry Economics, Econometrics & Finance Education Health Professions Languange, Linguistic, Communication & Media Law, Crime, Criminology & Criminal Justice Medicine & Pharmacology Nursing Public Health Social Sciences

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Ekstrak Daun Bandotan (Ageratum conyzoides lin) Memperbaiki Perilaku Depresi pada Mus Musculus Melanie Ajeng Pratama; Muhammad Alim Jaya; Hanna Aulia Namirah; Ilma Khaerina Amaliyah Bakhtiar; Suci Noviyanah Ansary
Jurnal Ilmiah Universitas Batanghari Jambi Vol 24, No 3 (2024): Oktober
Publisher : Universitas Batanghari Jambi

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.33087/jiubj.v24i3.5556

Abstract

This study aims to assess immobility time in Sham group mice (Mus musculus), assess the effect of fluoxetine antidepressant on immobility time in mice (Mus musculus), assess the impact of bandotan leaf extract antidepressant (Ageratum conyzoides lin) on immobility time in mice (Mus musculus), evaluate the antidepressant effectiveness of the combination of bandotan leaf extract (Ageratum conyzoides lin) with fluoxetine on immobility time in mice (Mus musculus), and compare the efficacy of the four groups, namely group 1 (Sham), group 2 (fluoxetine), group 3 (bandotan leaf extract (Ageratum conyzoides lin)), and group 4 (Fluoxetine with bandotan leaf extract (Ageratum conyzoides lin)). This study uses a type of quantitative approach and pure experimental method (true experimental research) with Posttest only Control Group Design research design. The results showed that the mean immobility time in mice (Mus musculus) group 1 (Sham) was for 34 ± 22.1 seconds. The average immobility time in mice (Mus musculus) group 2 (Fluoxetine) is for 162.5 ± 44.43 seconds. The average immobility time in mice (Mus musculus) group 3 (Bandotan leaf extract) was 172.67 ± 40.5 seconds. The average immobility time in mice (Mus musculus) group 4 (Combination of fluoxetine with bandotan leaf extract) was 118.83 ± 24.1 seconds. The combination of fluoxetine with bandotan leaf extract has significance (p-value 0.039 <0.05) as an antidepressant in reducing immobility time in mice so that bandotan leaves can act as adjuvant therapy.
Profil Neuropati Perifer Berdasarkan Skor Pain DETECT pada Penderita Diabetes Melitus Tipe 2 yang Menggunakan Metformin di Puskesmas Unaaha Joni, Ananda Sariah Dinara; Mangarengi , Yusriani; Ansary, Suci Noviyanah; Nur, Muhammad Jabal; Muchsin , Achmad Harun
Borneo Journal of Medical Laboratory Technology Vol. 7 No. 2 (2025): Borneo Journal of Medical Laboratory Technology
Publisher : Institute for Research and Community Services Universitas Muhammadiyah Palangkaraya

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.33084/bjmlt.v7i2.9500

Abstract

Diabetes melitus tipe 2 menunjukkan peningkatan prevalensi di Indonesia dari 6,9% (2013) menjadi 8,5% (2018). Di Sulawesi Tenggara khususnya, prevalensi diabetes meningkat dari 1,1% menjadi 1,3% dalam periode yang sama. Kabupaten Konawe sendiri mencatat prevalensi diabetes sebesar 1,77%, lebih tinggi dibandingkan wilayah lainnya seperti Kota Bau-Bau dan Kabupaten Konawe Kepulauan. Neuropati perifer merupakan komplikasi utama diabetes (45,6%), dan penggunaan metformin sebagai terapi lini pertama telah dikaitkan dengan defisiensi vitamin B12 yang dapat meningkatkan risiko neuropati perifer hingga 84%. Penelitian menunjukkan bahwa penggunaan metformin jangka panjang dapat menyebabkan defisiensi vitamin B12 melalui gangguan penyerapan di usus, yang pada gilirannya menyebabkan peningkatan kadar homosistein dan asam metilmalonat yang dapat memicu kerusakan saraf perifer. Pain DETECT dipilih sebagai instrumen skrining karena memiliki sensitivitas 85% dan spesifisitas 80% dalam mendeteksi komponen nyeri neuropatik. Tingginya prevalensi diabetes melitus tipe 2 di Kabupaten Konawe, risiko komplikasi neuropati perifer pada penggunaan metformin jangka panjang, serta belum adanya data komprehensif mengenai profil neuropati perifer berdasarkan skor Pain DETECT di Puskesmas Unaaha menjadi dasar pentingnya penelitian ini. Hasil penelitian diharapkan dapat memberikan gambaran nyata tentang kejadian neuropati perifer dan menjadi dasar untuk strategi pencegahan serta penanganan yang lebih baik.
Characteristics of Risk Factors and Clinical Manifestations of Non-Hemorrhagic Stroke In Patients At Ibnu Sina Hospital, Makassar, 2023–2024 Muh. Althaf Firjatullah; Erlin Syahril; Suci Noviyanah Ansary; Moch. Erwin Rachman; Dwi Pratiwi
AVERROUS: Jurnal Kedokteran dan Kesehatan Malikussaleh Averrous, Volume 11 No.2 November 2025
Publisher : Fakultas Kedokteran Universitas Malikussaleh

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.29103/averrous.v11i2.25421

Abstract

Non-hemorrhagic stroke is the most common type of stroke and a leading cause of morbidity and disability. This condition is generally triggered by blood flow disorders due to atherosclerosis, thrombosis, or embolism, with clinical manifestations such as sudden weakness, speech disorders, and decreased consciousness. In Indonesia, including South Sulawesi, the prevalence of stroke remains high, making the identification of risk factors and clinical symptoms crucial for optimal management. This study aims to describe in detail the risk factors for non-hemorrhagic stroke in patients recorded in the medical records of Ibnu Sina YW UMI Hospital in Makassar from 2023 to 2024, as well as to describe in detail the clinical manifestations of non-hemorrhagic stroke in patients recorded in the medical records of Ibnu Sina YW UMI Hospital in Makassar from 2023 to 2024. This study was conducted using a descriptive design through a cross-sectional approach. This type of research is quantitative. The results showed that the most dominant risk factor in non-hemorrhagic stroke patients at Ibnu Sina YW UMI Hospital in Makassar in 2023–2024 was hypertension (92.3%). Other risk factors found were family history (57.7%), genetic factors (53.8%), diabetes mellitus (23.1%), history of heart disease (13.5%), and dyslipidemia (11.5%). These findings indicate that the majority of patients had more than one risk factor, with hypertension being the main factor contributing to cerebral ischemia. The most common clinical manifestations were hemiparesis (90.4%), followed by vertigo (44.2%), ataxia (36.5%), aphasia (34.6%), nausea and vomiting (19.2%), and hemianesthesia (11.5%). This pattern shows that neurological deficits in the form of motor disorders are the most prominent symptoms in non-hemorrhagic stroke patients. This study shows that hypertension is the most dominant risk factor in non-hemorrhagic stroke patients, accompanied by family history and genetic factors. The most common clinical manifestations were hemiparesis, followed by vertigo, ataxia, and aphasia. These findings emphasize the importance of early detection of risk factors and recognition of characteristic neurological symptoms for the optimization of non-hemorrhagic stroke management.
Uji Efektivitas Infusa Daun Kelor (Moringa oleifera) terhadap Kadar Glukosa Darah pada Tikus Putih (Rattus novergicus) dengan Obesitas K, Cecy Anggriani H.; Irmayanti, Irmayanti; Maharani, Ratih Natasha; Kamaluddin , Irna Diyana Kartika; Ansary , Suci Noviyanah
Borneo Journal of Medical Laboratory Technology Vol. 8 No. 2 (2026): Borneo Journal of Medical Laboratory Technology
Publisher : Institute for Research and Community Services Universitas Muhammadiyah Palangkaraya

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.33084/bjmlt.v8i2.12232

Abstract

Obesitas berhubungan erat dengan hiperglikemia dan peningkatan risiko diabetes melitus, yang prevalensinya terus meningkat di Indonesia. Terapi farmakologis seperti metformin efektif menurunkan glukosa darah, namun penggunaan jangka panjang memiliki keterbatasan. Daun kelor (Moringa oleifera) mengandung senyawa bioaktif dan antioksidan yang berpotensi sebagai terapi nonfarmakologis penurun glukosa darah. Penelitian ini bertujuan untuk mengetahui efektivitas infusa daun kelor (Moringa oleifera) terhadap penurunan kadar glukosa darah  pada tikus putih (Rattus novergicus) dengan obesitas. Jenis penelitian yang digunakan pada penelitian ini adalah kuantitatif metode eksperimental laboratories dengan menggunakan desain penelitian pre and post test control group design dengan menggunakan tikus putih (Rattus novergicus) yang obesitas sebagai hewan coba untuk mengetahui efek dari pemberian infusa daun kelor (Moringa oleifera) terhadap penurunan kadar glukosa darah tikus putih yang obesitas. Hasil penelitian menunjukkan bahwa pemberian infusa daun kelor (Moringa oleifera) pada tikus putih (Rattus norvegicus) obesitas menyebabkan penurunan kadar glukosa darah secara signifikan dibandingkan kelompok tanpa perlakuan. Efektivitas penurunan glukosa darah meningkat seiring dengan peningkatan dosis, dengan dosis 800 mg/KgBB menunjukkan penurunan kadar glukosa darah paling besar dan sebanding dengan pemberian metformin. Dapat disimpulkan bahwa infusa daun kelor (Moringa oleifera) efektif menurunkan kadar glukosa darah pada tikus putih obesitas, dengan dosis 800 mg/KgBB sebagai dosis paling optimal.
EFIKASI EKSTRAK AKAR QUSTHUL HINDI (SAUSSUREA COSTUS) SEBAGAI ANTIBIOTIK TERHADAP BAKTERI KLEBSIELLA PNEUMONIAE Adhelia Zalsabilah Basir; Edward Pandu Wiriansya; Inna Mutmainnah Musa; Suci Noviyanah Ansary; Dwi Anggita
Integrative Perspectives of Social and Science Journal Vol. 3 No. 05 Mei (2026): Integrative Perspectives of Social and Science Journal
Publisher : PT Wahana Global Education

Show Abstract | Download Original | Original Source | Check in Google Scholar

Abstract

Klebsiella pneumoniae merupakan bakteri yang telah resisten terhadap beberapa antibiotik, peningkatan resistensi menjadi salah satu masalah kesehatan utama dan membutuhkan perhatian segera. Mengetahui kandungan dan aktivitas antibakteri ekstrak etanol 96% akar Qusthul Hindi (Saussurea costus) terhadap bakteri Klebsiella pneumoniae. Skrining fitokimia dilakukan menggunakan uji tabung dan uji aktivitas antibakteri menggunakan metode disc diffucion menggunakan cakram dengan 4 konsentrasi dan kontrol positif yang digunakan antibiotik Ciprofloxacin 500 mg serta kontrol negatif menggunakan aquadest. Ekstrak akar Qustul Hindi (Saussurea costus) memiliki senyawa aktif yaitu Alkaloid, Terpenoid, Saponin, Steroid, Tanin, dan Flavonoid. Hasil uji antibakteri menunjukkan adanya perbedaan zona hambat antar perlakuan. Pada konsentrasi 25%, 50%, 100% dan 200% dengan zona hambat yang terbentuk masing-masing adalah 15 mm, 17 mm, 19 mm dan 29 mm. Kontrol positif zona hambat yang terbentuk 24 mm dan kontrol negatif dengan aquadest steril tidak terbentuk zona hambat. Ekstrak akar Qusthul Hindi (Saussurea costus) memiliki aktivitas antibakteri terhadap bakteri Klebsiella pneumoniae dan konsentrasi 200% lebih sensitif menghambat bakteri Klebsiella pneumoniae dibangdingkan antibiotik Ciprofloxacin 500 mg.
Deteksi dini faktor risiko penyakit tidak menular melalui edukasi dan skrining kesehatan pada petugas kebersihan kampus di Makassar Sigit Dwi Pramono; Berry Erida Hasbi; Suci Noviyanah Ansary
Jurnal Pengabdian Masyarakat: Humanity and Medicine Vol 7 No 2 (2026): Jurnal Pengabdian Masyarakat: Humanity and Medicine
Publisher : Fakultas Kedokteran Universitas Sriwijaya

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.32539/Hummed.V7l2.229

Abstract

Early detection of non-communicable disease risk factors through health education and screening among campus cleaning staff in Makassar. Non-communicable diseases are the leading cause of death worldwide and in Indonesia, yet cleaning staff as support workers in higher education institutions are rarely targeted by early detection programmes. This community service activity aimed to detect non-communicable disease risk factors early and to deliver health education to cleaning staff at the Faculty of Medicine, Universitas Muslim Indonesia, Makassar. Conducted on 29 August 2025 using a participatory approach, it comprised three integrated stages: group health education, health screening, and individual counselling. Screening covered body weight, height, waist circumference, blood pressure, random blood glucose, and total cholesterol. All cleaning staff on duty were enrolled by total sampling, and the data were analysed descriptively. Of the 36 participants, 32 (88.9%) were women, with a mean age of 42.6 ± 11.9 years, and 23 (63.9%) had completed junior secondary education or less. Obesity was found in 18 participants (50.0%) and overweight in 8 (22.2%). Central obesity was identified in 23 participants (63.9%), comprising 21 of 32 women (65.6%) and 2 of 4 men (50.0%). Suboptimal blood pressure was found in 25 participants (69.4%), of whom 16 (44.4%) met the criteria for hypertension. Five participants (13.9%) were prediabetic and 3 (8.3%) diabetic, while 4 (11.1%) had borderline total cholesterol. All participants with abnormal results received counselling and referral to primary health care. These findings confirm a high burden of non-communicable disease risk factors among cleaning staff, particularly women.
Co-Authors Adhelia Zalsabilah Basir Berry Erida Hasbi Dwi Anggita Dwi Pratiwi Erlin Syahril Hanna Aulia Namirah Ilma Khaerina Amaliyah Bakhtiar Inna Mutmainnah Musa Irmayanti Irmayanti, Irmayanti Joni, Ananda Sariah Dinara K, Cecy Anggriani H. Kamaluddin , Irna Diyana Kartika Maharani, Ratih Natasha Mangarengi , Yusriani Melanie Ajeng Pratama Moch. Erwin Rachman Muchsin , Achmad Harun Muh. Althaf Firjatullah Muhammad Alim Jaya Muhammad Jabal Nur, Muhammad Jabal Sigit Dwi Pramono Wiriansya, Edward Pandu