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Zosteriform cutaneous metastases from a carcinoma mammae Widiasri, Kharisma Yuliasis; Sayekti, Ayu Wikan; Febiyanto, Novian; Wahyuanggradewi, Elliana; Giantoro, Jeffrey; Pudjiati, Satiti Retno; Rinonce, Hanggoro Tri; Siswati, Agnes Sri
Journal of General - Procedural Dermatology & Venereology Indonesia Vol. 7, No. 1
Publisher : UI Scholars Hub

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Abstract

Background: Cutaneous metastases were reported in 18.6-26.5% of breast cancer patients. Zosteriform cutaneous metastasis is an unusual and rare morphological variant. Clinicians, especially dermatovenereologists, should consider dermatomal cutaneous metastases in oncology patients aside from herpes zoster, which is common in this population. Case Illustration: A 62-year-old woman presented with clustered papules and vesicles with an erythematous base, sometimes painful, on the right side of the chest in T5-T7 dermatomal distribution of 1-month duration. She had undergone a radical mastectomy for breast carcinoma and had been receiving chemoradiotherapy, which was completed in March 2018. A diagnosis of zosteriform cutaneous metastases was established after discovering malignant cells in the representative lesion via biopsy, similar to those sampled from the previous cancerous right mammary tissue. Discussion: Zosteriform cutaneous metastasis is a rare occurrence, with a variety of clinical backgrounds, morphological, and histological features that can influence the clinical course of the disease. The mechanism for the occurrence of zosteriform cutaneous metastasis remains uncertain; several studies reported possible causes: Koebner-like reactions at the site of previous herpes zoster infections, perineural lymphatic spread, spread through blood vessels associated with the dorsal ganglion, unintentional implantation during surgery, direct invasion of the underlying structure (primary cancer), and spread from the lymphatic system. This case suits the diagnosis of zosteriform cutaneous metastases based on lesion morphology, location, distribution, and histopathological features matching those of the primary tumor. Conclusion: Metastatic disease should be considered in the differential diagnosis of zosteriform rash in oncology patients.
UJI STABILITAS KADAR BAHAN KONTROL POOLED SERA PEMERIKSAAN KIMIA KLINIK TERHADAP WAKTU DAN SUHU PENYIMPANAN Setiawan, Heru; Semendawai, Muhammad Yusuf; Febiyanto, Novian
Jurnal Fisioterapi dan Kesehatan Indonesia Vol 4 No 02 (2024): Jurnal Fisioterapi dan Kesehatan Indonesia
Publisher : Ikatan Fisioterapi Indonesia cabang kota bekasi

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.59946/jfki.2024.356

Abstract

In providing quality assurance for laboratory examinations, it is necessary to ensure quality by examining control materials. Pooled sera was chosen as a control material because the use of commercial control materials is relatively expensive and if the specimens examined are of human origin, it is better to use control materials of human origin as well. The use of pooled sera must be stable over a long period of time. The selection of HDL-Cholesterol and AST parameters is expected to be representative in metabolic and enzymatic examinations. The aim of the research was to determine the stability of pooled sera control materials level in clinical chemistry tests against storage time and temperature. This research is an experimental study, pooled sera were treated at storage time of 0, 1, 2, 3, 7, 14, 28, and 35 days and storage temperature (-5ºC and -20ºC) then HDL-Cholesterol and AST levels were measured repeatedly 3 times each. Data analysis used the repeated measure ANOVA test with 95% confidence level. The results showed that the test for the difference in average HDL-Cholesterol levels for each treatment had a value of p=0.002 < α=0.05, and the test for the difference in average AST levels for each treatment had a value of p=0.081 < α=0, 05. The conclusion of this study is that there is a significant difference between HDL-Cholesterol levels in each treatment (unstable) and there is no significant difference between AST levels in each treatment (stable).
Measurement of Ultraviolet-B (UVB) Minimum Erythema Dosage (MED) Based on Sun Exposure as the Basis of Sunlight Phototherapy: Study of Skin Type III or IV at Various Altitudes in Indonesia Meidiyanti, Prima; Radiono, Sunardi; Stella, Maureen Miracle; Febiyanto, Novian; Arief Budiyanto
Berkala Ilmu Kesehatan Kulit dan Kelamin Vol. 37 No. 3 (2025): DECEMBER
Publisher : Faculty of Medicine, Universitas Airlangga

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.20473/bikkk.V37.3.2025.185-189

Abstract

Background: Phototherapy facilities for skin diseases are not widely available in Indonesia. No studies have yet measured the duration of sunbathing to achieve a minimal erythema dose (MED) in healthy volunteers at various altitudes. Purpose: This study calculates the duration of sunbathing to achieve the MED at various altitudes. Methods: This study was conducted in various regions of Yogyakarta, Indonesia, with latitude 7◦15’-8◦15’ S and 110◦5’-110◦4’ E, within the Yogyakarta equinox period by including three places with different altitude groups at 10:00 WIB (UTC+7). Forty-eight healthy individuals of skin type III or IV were exposed to sunlight using a photo-opaque template with 8 squares, each with 1 x 1 cm2 holes. The squares will receive an increase in exposure duration of as many as 250 seconds. Result: There was a significant difference in the mean UVB intensity between all heights (p <0.05). The average duration of sunbathing to reach MED at an altitude of 0-300 masl, > 300-600 masl, and > 600-950 masl are 22 minutes 40 seconds, 20 minutes 34 seconds, and 18 minutes 14 seconds, respectively. There is no significant difference in the duration of sunbathing between altitudes of 0-300 masl and 300-600 masl and between 300-600 masl and 600-950 masl (p> 0.05). However, there was a significant difference in the duration of sunbathing between the altitudes of 0-300 masl and 600-950 masl (p <0.05). Conclusion: A difference exists in the duration of sunbathing required to achieve MED at altitudes greater than 600 masl