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All Journal SAINS MEDIKA : JURNAL KEDOKTERAN DAN KESEHATAN Berkala Ilmu Kesehatan Kulit dan Kelamin Damianus Journal of Medicine Indonesian Journal of Tropical and Infectious Disease YARSI Medical Journal Indonesian Journal of Global Health research

Stella, Maureen Miracle

Unknown Affiliation

Author-ID : 1501839

Earth & Planetary Sciences Education Health Professions Immunology & microbiology Languange, Linguistic, Communication & Media Medicine & Pharmacology Nursing Public Health

Published : 8 Documents Claim Missing Document

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Articles

ATROPINE 0.01% AS A POTENTIAL MYOPIA PREVENTION IN CHILDREN WITH DOSAGE EFFECTIVITY COMPARISON: A LITERATURE REVIEW Ivan, Ignatius; Stella, Maureen Miracle; Santosa, Mariani
Jurnal Kedokteran YARSI Vol 27, No 3 (2019): SEPTEMBER - DESEMBER 2019
Publisher : Lembaga Penelitian Universitas YARSI

Myopia (long-sightedness) is one of the many problems of vision disorder occurring around the world and being 1 in 5 eye conditions that becoming a priority at the World Health Organization's Global Intitiative for the Elimination of Avoidable Blindness. Many methods of preventing myopia development have been sought. Atropine is an alkaloid derived herbal plant Atropa belladonna which acts as a muscarinic acetylcholine receptor antagonist that has a strong nonselective competitive affinity on the five types of muskarinic acetylcholine receptors (M1-M5) that weaken the muscles of the ciliary and iris and causes the reduction of accommodation and the occurrence of pupil dilation. Recent research found that with the use of low dose atropine (0.01%), in addition to the side effects inflicted more minimal, effectiveness in the long time period shows better results. Until now, the mechanism of atropine is still experiencing debate whether working on an accommodating or non-accommodating pathway. But recent research suggests the possibility of working mechanism of this drug is through a non-accommodating pathway i.e. on GABAergic, dopaminergic as well as involving nitric oxide (NO) role to help inhibit the progression of myopia. In research and advanced scientific studies, it can be researched regarding the pathways of atropine mechanism and its advantages and disadvantages at any dose of atropine given to myopia sufferers using the latest literature sources.

Skin manifestations in patients with covid-19: A literature review Gunawan, Danny; Stella, Maureen Miracle; Sidharta, Veronika Maria
Sains Medika: Jurnal Kedokteran dan Kesehatan Vol 13, No 1 (2022): June 2022
Publisher : Faculty of Medicine, Universitas Islam Sultan Agung (UNISSULA), Indonesia

Coronavirus disease (COVID-19) is an infectious disease caused by the SARS-CoV-2 virus. In December 2019, cases of pneumonia with unknown cause were first reported in Wuhan, Hubei Province, China. Confirmed cases and death rates due to COVID-19 in the world are still increasing. One part of the body that is affected and causes clinical symptoms in COVID-19 is the skin. This review aims to describe and analyze cutaneous manifestation in COVID-19. This study method is a review of the literature sourced from Google Scholar and PubMed. The literature was selected using English language criteria, using the clinical study method in the form of case reports. Meanwhile, literature review, systematic literature, and meta-analysis were excluded. Journal searches were carried out using the keywords "skin" OR "cutaneous" AND "manifestation" AND "COVID-19" OR "coronavirus". The skin manifestations of COVID-19 have been observed. The most common clinical symptoms of COVID-19 were fever (47%), dry or productive cough (25%), sore throat (16%), generalized sore throat (6%), and pain (5%). However, currently there has been a shift in the approach to diagnosing COVID-19 because it can cause symptoms in other organ systems, one of which is skin manifestations. There are early reports of skin involvement (erythematous rash, extensive urticaria, and chickenpox-like vesicles) occurring in 20% of patients in the course of the COVID-19 disease. In addition, several case reports provide descriptions of petechiae and chilblains. Based on the cases that have been reported, patients with COVID-19 who have manifestations on the skin can give a picture of maculopapular eruptions, vesicular eruptions, petechiae, and also childblains.

Plasmodium falciparum Breath Metabolomics (Breathomics) Analysis as a Non-Invasive Practical Method to Diagnose Malaria in Pediatric Ivan, Ignatius; Stella, Maureen Miracle; Tandarto, Kevin; Budiman, Fanny; Joprang, Freggy Spicano
Indonesian Journal of Tropical and Infectious Disease Vol. 9 No. 1 (2021)
Publisher : Institute of Topical Disease Universitas Airlangga

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.20473/ijtid.v9i1.24069

Children under 5 years of age are particularly vulnerable to malaria. Malaria has caused 445,000 deaths worldwide. Currently, rapid diagnostic tests (RDTs) are the fastest method to diagnose malaria. However, there are limitations that exist such as low sensitivity in detecting infections with low parasitemia. Practical, non-invasive and high ability tests to detect parasite are needed to find specific biomarkers for P. falciparum infection to determine the potential of P. falciparum 4 thioether in breathomics analysis by GC-MS as a practical non-invasive method in diagnosing malaria in pediatrics. Literature reviews from Google Scholar and ProQuest were published no later than the last 5 years. The concept of breathomics is that the breath's volatile organic compounds (VOCs) profile is altered when the health condition changes. Breath samples from individuals infected with P. falciparum malaria were taken by exhalation. Through GC-MS analysis, it was found that 4 thioether compounds (allyl methyl sulfide (AMS), 1-methylthio-propane, (Z) -1-methylthio-1-propene and (E) -1-methylthio-1-propene) underwent a significant change in concentration during the infection. Based on experiments conducted on mice and humans, the breathomics method is known to be able to detect parasitemia levels up to <100 parasites/µL, has a sensitivity level of about 71% to 91% and a specificity of about 75% to 94%. The discovery of 4 thioether compounds by GC-MS is a strong indication of malaria, because it has the potential for high sensitivity and specificity, and the detection power exceeds the ability of RDTs.

Zoliflodacin, A Novel Antimirobial Agent Against neisseria Gonorhoeae: A Systematic Rreview of Quasi-Experimental Studies Matthew, Franklind; Stella, Maureen Miracle; Tandarto, Kevin; Regina, Regina
Berkala Ilmu Kesehatan Kulit dan Kelamin Vol. 36 No. 1 (2024): APRIL
Publisher : Faculty of Medicine, Universitas Airlangga

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.20473/bikk.V36.1.2024.68-74

Background: The gram-negative bacteria Neisseria gonorrhoeae is the source of the STI known as gonorrhea. N. gonorrhoeae can adapt well to humans as a host and become a pathogen with sophisticated mechanisms to avoid the innate immune response as well as suppress the adaptive immune response. Lately, zoliflodacin was shown to have antibacterial activity against N. gonorrhoeae. Purpose: The aim of this study is to evaluate the antibacterial activity of zoliflodacin against N. gonorrhoeae. Methods: We followed the PRISMA 2020 guidelines to systematically search and collect literature in the following databases: ProQuest, EBSCOhost, PubMed, ScienceDirect, Taylor&Francis, SAGE, JSTOR, and Wiley, without time limitation (until October 9th, 2022). Titles and abstracts were reviewed for relevance. The inclusion criteria were original article written in English that investigated the effects of zoliflodacin in patients with gonorrhea. From 177 studies, we retrieved five studies for this study, published between 2015 and 2021. Results: Zoliflodacin was highly active in vitro against N. gonorrhoeae isolates from European countries, China, Thailand, and South Africa, and also showed potent antimicrobial activity against multi-resistant N. gonorrhoeae isolates in South Korea. There were three different kinds of minimum inhibitory concentration (MIC) evaluated, with the following results: modal MIC (0.064-0.25 Î¼g/mL), MIC50 (0.03-0.125 Î¼g/mL), and MIC90 (0.06-0.25 Î¼g/mL). There was no cross-resistance to antimicrobials currently or previously used for gonorrhea treatment. This MIC range could be used for further studies.

Wound Healing Potency of Edible Bird’s Nest Alysia, Jessica; Stella, Maureen Miracle; Widjaja, Maureen; Wijaya, Lorettha
Indonesian Journal of Global Health Research Vol 7 No 1 (2025): Indonesian Journal of Global Health Research
Publisher : GLOBAL HEALTH SCIENCE GROUP

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.37287/ijghr.v7i1.4065

Edible bird's nest (EBN) or swiftlet's nest has recently been used extensively in regenerative medicine. This study aims to give a more thorough overview on the efficacy of EBN as a wound-healing agent. Method: We searched literature through several databases: Google Scholar, PubMed, Proquest, JSTOR, EBSCOhost, and SAGE. The keywords used were "bird nest, scar, wound healing" and their synonyms. The inclusion criteria were original articles written in English and assessed the effects of EBN in the wound healing process. We found 9 in vitro studies and 4 in vivo studies reporting wound healing effect of EBN, both macroscopically and microscopically. EBN could increase wound healing process through several mechanisms, such as cell proliferation, anti-oxidants, anti-inflammation, increased collagen synthesis, and tissue hydration. EBN has the potential to be used as a natural bioactive agent to increase the wound healing process.

Perception and Behavior in Skincare Routine During the Covid-19 Pandemic Hidajat, Inneke Jane; Stella, Maureen Miracle; Alysia, Jessica; Widjaja, Maureen; Zaskia, Rika; Regina, Regina
Indonesian Journal of Global Health Research Vol 7 No 3 (2025): Indonesian Journal of Global Health Research
Publisher : GLOBAL HEALTH SCIENCE GROUP

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.37287/ijghr.v7i3.6008

In the COVID-19 pandemic, several policies have been implemented such as the use of masks and social distancing. This has an impact on lifestyle changes such as skincare routines. The aim of this study was to obtain a demographic, behavioral, and perception overview of skincare use before and during the pandemic in medical students. This cross-sectional study was conducted by distributing a Google form questionnaire to FKIK Unika Atma Jaya students from the 2016-2021 intake. The inclusion criteria used were as follows: (1) FKIK Atma Jaya students from the 2016-2021 intake; (2) Students who completed the questionnaire until the end. Medical students demonstrated a high level of skincare knowledge but showed uncertainty regarding product composition and safety aspects. Their behavior indicated a strong focus on appearance and trust in brand quality, though opinions were divided on halal certification. Despite a strong demand for skincare products, makeup usage declined. Most respondents were aware of skincare benefits and potential side effects, but uncertainty arose about ingredients and disinfecting. This study explored the perceptions and behaviors of medical students regarding skincare use before and during the COVID-19 pandemic. Health promotion is urgently needed to prevent skin disorders due to skincare.

Terapi Kombinasi Montelukast dan Desloratadin pada Pasien Urtikaria Akut yang Tidak Responsif dengan Antihistamin dan Kortikosteroid Regina, Regina; Wijaya, Lorettha; Stella, Maureen Miracle
Bahasa Indonesia Vol 24 No 1 (2025): Damianus Journal of Medicine
Publisher : Atma Jaya Catholic University of Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.25170/djm.v24i1.3220

Introduction: Urticaria is a common skin disease, characterized by localized edema that appears suddenly and disappears within 24 hours. Antihitamin-H1 is the drug of choice for urticaria which is sometimes combined with systemic corticosteroids. The use of montelukast in cases of urticaria is still rarely reported. Case Report: A 21-year-old woman came with complaint of itchy bumps all over her body with a dominant burning sensation since 5 days ago. Complaint remained unchanged even after administering up to four doses of desloratadine and a combination of 16 mg methylprednisolone. The complaint finally improved after the patient was given montelukast 10 mg per day combined with desloratadine 5 mg twice a day. Discussion: Leukotriene is a lipid mediator that can increase vasopermeability and vasodilation in the skin. The improvement in symptoms that occurred after the combination therapy of montelukast and desloratadine proved the involvement of leukotrienes in the pathogenesis of this patient's case of acute urticaria. Conclusion: Combination therapy with montelukast and desloratadine may be useful in some cases of acute urticaria. Further studies with sufficient control may be conducted to determine the effectiveness of montelukast in combination with antihistamines for cases of acute urticaria.

Measurement of Ultraviolet-B (UVB) Minimum Erythema Dosage (MED) Based on Sun Exposure as the Basis of Sunlight Phototherapy: Study of Skin Type III or IV at Various Altitudes in Indonesia Meidiyanti, Prima; Radiono, Sunardi; Stella, Maureen Miracle; Febiyanto, Novian; Arief Budiyanto
Berkala Ilmu Kesehatan Kulit dan Kelamin Vol. 37 No. 3 (2025): DECEMBER
Publisher : Faculty of Medicine, Universitas Airlangga

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.20473/bikkk.V37.3.2025.185-189

Background: Phototherapy facilities for skin diseases are not widely available in Indonesia. No studies have yet measured the duration of sunbathing to achieve a minimal erythema dose (MED) in healthy volunteers at various altitudes. Purpose: This study calculates the duration of sunbathing to achieve the MED at various altitudes. Methods: This study was conducted in various regions of Yogyakarta, Indonesia, with latitude 7◦15’-8◦15’ S and 110◦5’-110◦4’ E, within the Yogyakarta equinox period by including three places with different altitude groups at 10:00 WIB (UTC+7). Forty-eight healthy individuals of skin type III or IV were exposed to sunlight using a photo-opaque template with 8 squares, each with 1 x 1 cm2 holes. The squares will receive an increase in exposure duration of as many as 250 seconds. Result: There was a significant difference in the mean UVB intensity between all heights (p <0.05). The average duration of sunbathing to reach MED at an altitude of 0-300 masl, > 300-600 masl, and > 600-950 masl are 22 minutes 40 seconds, 20 minutes 34 seconds, and 18 minutes 14 seconds, respectively. There is no significant difference in the duration of sunbathing between altitudes of 0-300 masl and 300-600 masl and between 300-600 masl and 600-950 masl (p> 0.05). However, there was a significant difference in the duration of sunbathing between the altitudes of 0-300 masl and 600-950 masl (p <0.05). Conclusion: A difference exists in the duration of sunbathing required to achieve MED at altitudes greater than 600 masl

Co-Authors Alysia, Jessica Arief Budiyanto Budiman, Fanny Febiyanto, Novian Gunawan, Danny Hidajat, Inneke Jane Ivan, Ignatius Joprang, Freggy Spicano Lorettha Wijaya Mariani Santosa, Mariani Matthew, Franklind Meidiyanti, Prima Regina Regina Tandarto, Kevin Veronika Maria Sidharta Widjaja, Maureen Zaskia, Rika

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