<![CDATA[Abstract Background: Menopause syndrome is a set of symptoms or complaints that women feel when they start entering menopause. The complaints in question are physical complaints and psychological complaints. It causes discomfort that interferes with daily work so that it can reduce the quality of life of menopausal women. Purpose: To determine the relationship of menopausal syndrome with the quality of life of menopausal women in the work area of the South Alalak Health Center, Banjarmasin City. Method: This study used a quantitative analytic survey with a cross-sectional approach. The population was 110 menopausal women in the work area of the South Alalak Health Center, Banjarmasin City. The sample was selected using purposive sampling techniques, as many as 87 respondents. Data analysis using SPSS with the Spearman Rank test. Results: The study showed 55 respondents (63.2%) did not experience menopausal syndrome, 28 respondents (32.2%) experienced mild menopausal syndrome, and 4 respondents (4.6%) experienced moderate menopausal syndrome. There were 29 respondents (33.3%) who had a poor quality of life, 54 respondents (62.1%) had a moderate quality of life, and 4 respondents (4.6%) had a good quality of life. The results of statistical tests using Rank Spearman stated that there was a relationship between menopausal syndrome and women's quality of life (p-value = 0.000, correlation coefficient = -0.739). Conclusion: There is a relationship between menopausal syndrome and the quality of life of women in the work area of the South Alalak Health Center, Banjarmasin City. The direction of the relationship is negative (unidirectional) which can be seen from the correlation coefficient, meaning that the higher the intensity of menopausal syndrome, the lower the level of quality of life. Suggestion: It is expected that the health center can continue to improve services for menopausal women and elderly posyandu. Keywords: Menopause; Menopause Syndrome; Quality of Life. Pendahuluan: Sindrom menopause merupakan sekumpulan gejala atau keluhan yang dirasakan wanita saat mulai memasuki masa menopause. Keluhan-keluhan yang dimaksud berupa keluhan fisik dan keluhan psikologis. Hal itu menimbulkan ketidaknyamanan yang mengganggu pekerjaan sehari-hari sehingga dapat menurunkan kualitas hidup wanita menopause. Tujuan: Untuk mengetahui hubungan sindrom menopause dengan kualitas hidup wanita menopause di wilayah kerja Puskesmas Alalak Selatan Kota Banjarmasin. Metode: Penelitian survei analitik kuantitatif dengan pendekatan cross-sectional. Populasi sebanyak 110 wanita menopause di wilayah kerja Puskesmas Alalak Selatan Kota Banjarmasin. Sampel dipilih menggunakan teknik purposive sampling sebanyak 87 responden. Analisis data menggunakan SPSS dengan uji Rank Spearman. Hasil: Penelitian menunjukkan 55 responden (63.2%) tidak mengalami sindrom menopause, 28 responden (32.2%) mengalami sindrom menopause kategori ringan, dan 4 responden (4.6%) mengalami sindrom menopause sedang. Ada 29 responden (33.3%) memiliki kualitas hidup buruk, 54 responden (62.1%) responden memiliki kualitas hidup sedang, dan 4 responden (4.6%) memiliki kualitas hidup baik. Hasil uji statistik menggunakan Rank Spearman menyatakan adanya hubungan antara sindrom menopause dengan kualitas hidup wanita (p-value = 0.000; correlation coefficient = -0.739). Simpulan: Ada hubungan sindrom menopause dengan kualitas hidup wanita di wilayah kerja Puskesmas Alalak Selatan Kota Banjarmasin. Arah hubungan bersifat negatif (tidak searah) yang dapat dilihat correlation coefficient, artinya semakin tinggi intensitas sindrom menopause maka semakin rendah tingkat kualitas hidup. Saran: Diharapkan puskesmas dapat terus meningkatkan pelayanan terhadap wanita menopause dan posyandu lansia. Kata Kunci: Kualitas Hidup; Menopause; Sindrom Menopause.]]>
