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All Journal JURNAL PESISIR DAN LAUT TROPIS
Rose OSE Mantiri
FPIK UNSRAT
Earth & Planetary Sciences

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AKTIVITAS SITOTOKSIK EKSTRAK KARANG LUNAK Xenia sp. DARI TELUK MANADO, PROVINSI SULAWESI UTARA Juniarti S Datula’bi; Robert A Bara; Fitje Losung; Remy EP Mangindaan; Ping A Angmalisang; Rose OSE Mantiri
JURNAL PESISIR DAN LAUT TROPIS Vol. 9 No. 3 (2021): JURNAL PESISIR DAN LAUT TROPIS
Publisher : Sam Ratulangi University

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.35800/jplt.9.3.2021.36523

Abstract

Bioactive compounds from the sea which are generally in the form of secondary metabolites have the potential to be developed as medicinal ingredients. Marine life can be used as an object of research and development, considering the many benefits that can be taken from the secondary metabolite compounds contained in it, especially compounds that have bioactivity. Soft corals are marine biota that have bioactivity, extracts from sost coral contain bioactive compounds that have cytotoxic, anti-tumor, anti-viral, anti-inflammatory, anti-fungal, anti-leukemic, and enzyme activity inhibitory properties. Some of the research results show that marine soft corals have a variety of structures and biological activities including antioxidant substances. Soft corals were extracted by maceration method and then evaporated. The cytotoxic activity of soft coral extract was tested using the BLSA method and then analyzed the data to find the concentration of mortality (LC50). The purpose of this study was to test the cytotoxic activity of soft coral Xenia sp. The results of this study were testing the cytotoxic activity of the sample Xenia sp., amounting to 20.89 ppm, and having strong toxic properties. Key words: BLSA, Soft coral Xenia sp., LC50, Cytotoxic
Co-Authors Fitje Losung Juniarti S Datula’bi Ping A Angmalisang Remy EP Mangindaan Robert A Bara