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All Journal JURNAL PESISIR DAN LAUT TROPIS
Remy EP Mangindaan
FPIK UNSRAT
Earth & Planetary Sciences

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AKTIVITAS SITOTOKSIK EKSTRAK KARANG LUNAK Xenia sp. DARI TELUK MANADO, PROVINSI SULAWESI UTARA Juniarti S Datula’bi; Robert A Bara; Fitje Losung; Remy EP Mangindaan; Ping A Angmalisang; Rose OSE Mantiri
JURNAL PESISIR DAN LAUT TROPIS Vol. 9 No. 3 (2021): JURNAL PESISIR DAN LAUT TROPIS
Publisher : Sam Ratulangi University

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.35800/jplt.9.3.2021.36523

Abstract

Bioactive compounds from the sea which are generally in the form of secondary metabolites have the potential to be developed as medicinal ingredients. Marine life can be used as an object of research and development, considering the many benefits that can be taken from the secondary metabolite compounds contained in it, especially compounds that have bioactivity. Soft corals are marine biota that have bioactivity, extracts from sost coral contain bioactive compounds that have cytotoxic, anti-tumor, anti-viral, anti-inflammatory, anti-fungal, anti-leukemic, and enzyme activity inhibitory properties. Some of the research results show that marine soft corals have a variety of structures and biological activities including antioxidant substances. Soft corals were extracted by maceration method and then evaporated. The cytotoxic activity of soft coral extract was tested using the BLSA method and then analyzed the data to find the concentration of mortality (LC50). The purpose of this study was to test the cytotoxic activity of soft coral Xenia sp. The results of this study were testing the cytotoxic activity of the sample Xenia sp., amounting to 20.89 ppm, and having strong toxic properties. Key words: BLSA, Soft coral Xenia sp., LC50, Cytotoxic
KARAKTERISTIK MORFOLOGI DAN AKTIVITAS ENZIM PROTEASE BAKTERI SIMBION NUDIBRANCH Sabrina I Hengkengbala; Rosita AJ Lintang; Deiske A sumilat; Remy EP Mangindaan; Elvy Like Ginting; Sipriana Tumembouw
JURNAL PESISIR DAN LAUT TROPIS Vol. 9 No. 3 (2021): JURNAL PESISIR DAN LAUT TROPIS
Publisher : Sam Ratulangi University

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.35800/jplt.9.3.2021.36672

Abstract

One type of enzyme whose application is very widespread is protease enzymes. Microorganisms that have not been widely explored as a source of protease enzymes are bacteria that are in conjunction with Nudibranch. The study aims to identify the morphological characteristics of bacteria, then determine the hydrolysis ability of protease enzymes from bacteria symbiont Nudibranch. Identification of morphological characteristics is done macroscopic, and microscopic with gram staining. Proteolytic activity tests are performed qualitatively by measuring the proteolytic index of bacteria grown on Skim Milk Agar medium. The results of macroscopic identification of symbiotic bacteria with Nudibranch are dominated by irregular colony shapes, undulated edges, growth of the entire colony has a flat height, milky white colony color, buttery texture and opaque bacterial colonies. Based on microscopic identification, two gram-negative isolates are obtained, namely RL.S14, S1.1.1, and gram positive isolates, namely AK.S00, AK.S01, AK.S02, AK.S03, S.PP1, RL.S6, S2.1.5, S2.2.1, S3.3.1, S3.3.4, RL.S10. Nudibranch symbiont Bacterial has colony cells were dominated by the diplobacillus form. The results of the protease activity test of Nudibranch symbiont bacteria showed that 12 positive isolates had proteolytic activity with the highest proteolytic index produced by isolate AK.S00, which was 2.5 mm. Keywords: Nudibranch, symbiotic bacteria, characteristics, protease
Co-Authors Deiske A Sumilat Elvy Like Ginting Fitje Losung Juniarti S Datula’bi Ping A Angmalisang Robert A Bara Rose OSE Mantiri Rosita AJ Lintang Sabrina I Hengkengbala Sipriana Tumembouw