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All Journal Majalah Kedokteran Gigi Indonesia Journal of Health and Nutrition Research
Abdullah, Johari Yap
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Dentistry Medicine & Pharmacology Nursing Public Health

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Titanium oxide coating and acid etching on platelet activation in dental implants Maharani, Adella Syvia; Ismiyati, Titik; Aditama, Pramudya; Abdullah, Johari Yap; Aziz, Ihwanul
Majalah Kedokteran Gigi Indonesia Vol 10, No 1 (2024): April
Publisher : Faculty of Dentistry, Universitas Gadjah Mada

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.22146/majkedgiind.94366

Abstract

Titanium is the most widely used dental implant material, but it requires surface treatment to improve osseointegration. While coating implants with TiO2, residue can arise, which may lead to contamination. To address this, 10% HF etching is added. This study investigated the effect of TiO2 coating using sputtering and HF etching on platelet activation in titanium dental implants. Laboratory experiments were conducted on titanium implants (Ø = 4 mm; length = 12 mm) treated with TiO2 coating and 10% HF etching. Twenty-four samples were divided into four groups (n = 6): Group I (TiO2), Group II (TiO2 + HF 5 min), Group III (TiO2 + HF 10 min), and Group IV (TiO2 + HF 20 min). Platelet activation was assessed using CD41 and CD62P expression markers. Data analysis employed one-way ANOVA and post hoc LSD test (p = 0.05). Platelet activation ranged from 20.31 ± 1.78% to 35.90 ± 3.81%. One-way ANOVA revealed a significant effect (p < 0.05) of both TiO2 coating and acid etching on activation. LSD post hoc test showed significant differences (p < 0.05) between all groups except for the 10 and 20-minute etching periods. TiO2 coating with 10 minutes of HF etching resulted in the optimal activation level.
How Osteoporosis Looks Like in CT Scan Images: An Alternative Osteoporosis Assessment Genisa, Maya; Abdullah, Johari Yap; MD Yusoff, Bazli Bin; Aryenti, Aryenti; Juniarti, Juniarti
Journal of Health and Nutrition Research Vol. 4 No. 2 (2025)
Publisher : Media Publikasi Cendekia Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.56303/jhnresearch.v4i2.393

Abstract

Osteoporosis is a silent degenerative disease that commonly affects the elderly, leading to decreased bone density and increased risk of fractures. Dual-Energy X-ray Absorptiometry (DEXA) is the standard tool for assessing Bone Mineral Density (BMD), but its limited availability and high cost in many healthcare facilities, especially in developing countries like Indonesia, necessitate alternative diagnostic methods. This study aims to assess the potential use of Computed Tomography (CT) scan images as a substitute for DEXA in detecting osteoporosis. The objective is to analyze bone texture attributes from CT images to differentiate between normal and osteoporotic bone structures. The method involved collecting CT scan data from patients at Hospital Universiti Sains Malaysia (HUSM). The vertebrae regions were segmented from the abdominal CT images using image processing techniques to isolate bone tissue. Four image-derived texture attributes—Roughness, Contrast, Greyscale, and Phase—were then extracted using MATLAB-based analysis. The results showed that osteoporotic bones had higher values in Roughness and Contrast, and lower values in Greyscale and Phase compared to normal bones. Among these, Roughness was identified as the most sensitive attribute in detecting changes associated with osteoporosis. These findings indicate that CT scan images, when analyzed through proper segmentation and texture evaluation, have the potential to serve as a viable alternative for osteoporosis screening, particularly in settings where DEXA is unavailable.
Co-Authors Adella Syvia Maharani Aryenti, Aryenti Ihwanul Aziz Juniarti Juniarti Maya Genisa MD Yusoff, Bazli Bin Pramudya Aditama Titik Ismiyati