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All Journal Jurnal Ilmu Kedokteran dan Kesehatan Cermin Dunia Kedokteran
Allatib, Arohid
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Biochemistry, Genetics & Molecular Biology Health Professions Immunology & microbiology Medicine & Pharmacology Public Health

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OPPORTUNITIES FOR THE APPLICATION OF THE GUT-BRAIN-AXIS MICROBIOTA FOR THE OPTIMIZATION OF NERVE GROWTH AND DEVELOPMENT IN INFANTS Allatib, Arohid; Azzahra, Zahwa Arsy; Widyaningrum, Immaculata; Januarta, Cahya Wahyudi
Jurnal Ilmu Kedokteran dan Kesehatan Vol 10, No 9 (2023): Volume 10 Nomor 9
Publisher : Prodi Kedokteran Fakultas Kedokteran Universitas Malahayati

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.33024/jikk.v9i10.11582

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Abstract: Opportunities for The Application of The Gut-Brain-Axis Microbiota for The Optimization of Nerve Growth and Development in Infants. Neurodevelopment in infants is very important and has a significant role in shaping their future intellectual, emotional, and physical capacities. Nerve cells (neurons) form a neural network in babies from the time of pregnancy. The interaction between the gut microbiota and the brain occurs through a pathway called the gut-brain axis. Studies have shown that gut microbiota influences brain function and human behavior. To find out the efforts that can be made to maximize the development of the baby's brain by utilizing the concept of the gut-brain-axis microbiota. Using literature review techniques from international articles in the 2013-2023 using specific keywords in PubMed, Cochrane, Embase, Scopus, Google Scholar, and Textbook. Efforts to improve neurodevelopment using the concept of a gut-brain-axis microbiota are essentially efforts to create a good microbiota balance in the gut.  These efforts include maintaining and maintaining the balance of the healthy microbiota of pregnant women, giving birth pre-vaginal, providing exclusive breast milk, reducing the use of antibiotics that are not required, providing complementary foods breast milk rich in probiotics and prebiotics, providing stimulus, and reduce the use of chemicals.  The concept of gut-brain-axis microbiota is very applicable to maximize neurodevelopment in infants starting by paying particular attention to the prenatal and postnatal periods.
Perbandingan Efikasi dan Keamanan Vaksin Influenza yang Dilemahkan dan Vaksin Influenza yang Dimatikan pada Anak dengan Asma: Tinjauan Sistematis dan Meta-Analisis: Analisis Allatib, Arohid; Putra, Handre; Shidiq, Mahfudz; Purba, Pedro; Viera, Viera
Cermin Dunia Kedokteran Vol 52 No 6 (2025): Kesehatan Jiwa
Publisher : PT Kalbe Farma Tbk.

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.55175/cdk.v52i6.1666

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Introduction: Asthma patients are at higher risk of experiencing respiratory morbidity due to influenza, vaccination is recommended for this group. This study aims to compare the efficacy and side effects between live-attenuated influenza vaccines (LAIV) and inactivated influenza vaccines (IIV) in asthmatic children. Methods: This research use PRISMA guidelines, with studies sourced from PubMed, Cochrane, and Embase. ROB2 and ROBINS were employed to assess the risk of bias. Quantitative analysis was performed using Review Manager v5.4. Results: A total of 4,753 samples were collected, consisting of 2,390 intervention patients and 2,363 control patients. The meta-analysis results showed that influenza infection was more likely to occur in patients who received the inactivated influenza vaccine [pooled OR = 0.58; 95% CI (0.43, 0.78)}. Conclusion: The recommended vaccine type is the live-attenuated influenza vaccine, as no significant differences in side effects were observed between the two vaccines.
Co-Authors Azzahra, Zahwa Arsy Januarta, Cahya Wahyudi Mahfudz Shidiq Purba, Pedro Putra, Handre Viera, Viera Widyaningrum, Immaculata