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STUDY LITERATURE: PATOMEKANISME GANGGUAN KOGNITIF PADA PASIEN HIPERTENSI Rahmadini, Nasyada Fadhila; Safitri, Nasywa Aulia; Padma Puspita, Ni Made Sri; Binti Amir, Nurul Aulia; Atari, Sicillia Putri; Paradhini, Tri Sastra; Hunaifi, Ilsa
Jurnal Ilmu Kedokteran dan Kesehatan Vol 10, No 12 (2023): Volume 10 Nomor 12
Publisher : Prodi Kedokteran Fakultas Kedokteran Universitas Malahayati

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.33024/jikk.v10i12.12751

Abstract

Abstract: Study Literature: Patomekanisme Gangguan Kognitif Pada Pasien Hipertensi. Menurut Konsensus Penatalaksanaan Hipertensi oleh Indonesian Society of Hypertension (INaSH), hipertensi emergensi merupakan situasi hipertensi derajat 3 yang diikuti dengan hypertension-mediated organ damage (HMOD) akut. Atau dapat didefinisikan sebagai peningkatan tekanan darah sistol dan diastol yang berada di atas 180/110 mm Hg. Hipertensi masih menjadi permasalahan global dan diperkirakan akan meningkat sebanyak 29% pada tahun 2025, dengan angka mortalitas mencapai 4,6%. Sekitar 75 juta atau 32% dari orang dewasa di Amerika Serikat mengalami hipertensi dengan sebanyak 1%-3% pasien dapat mengalami krisis hipertensi. Hipertensi memiliki hubungan yang erat dengan peningkatan risiko terjadinya disfungsi kognitif terutama pada individu lanjut usia. Ketika seseorang lansia mengalami hipertensi, akan terjadi gangguan umum pada beberapa mekanisme homeostasis termasuk regulasi aliran darah ke otak dan tekanan mikrovaskular. Salah satu contoh dari gangguan kognitif yang dapat terjadi adalah alzheimer.
Potensi Senyawa Kuersetin dalam Daun Jambu Biji (Psidium guajava L.) sebagai Pengobatan Demam Berdarah Dengue Safitri, Nasywa Aulia; Marwa Zileikhadira Manzalina; Muhammad Farras Abiyyu F; Nasyada Fadhila Rahmadini; Mahacita Andanalusia
Lombok Medical Journal Vol. 2 No. 3 (2023): Lombok Medical Journal Volume 2 Nomor 3
Publisher : Faculty of Medicine, Universitas Mataram

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.29303/lmj.v2i2.2851

Abstract

Abstract: Dengue is one of the most common mosquito-borne diseases in tropical and subtropical climates. So far there are no effective antivirals available for the treatment of DENV infection, which in this case requires alternative treatments that can be a cure as well as prevention for dengue fever. Alternative treatment that can be used is by using plants, one of which is guava. In guava leaves, there are various compounds that are efficacious as anti-dengue fever, namely flavonoid compounds such as quercetin and tannins which are believed to inhibit the growth of dengue viruses. The purpose of writing this manuscript is to discuss the potential of quercetin compounds in guava leaves in the management of dengue fever. Keywords: Dengue hemorrhagic fever, alternative medicine, antiviral, guava leaf, quercetin, ethnomedicine
Potensi Senyawa Kuersetin dalam Daun Jambu Biji (Psidium guajava L.) sebagai Pengobatan Demam Berdarah Dengue Safitri, Nasywa Aulia; Marwa Zileikhadira Manzalina; Muhammad Farras Abiyyu F; Nasyada Fadhila Rahmadini; Mahacita Andanalusia
Lombok Medical Journal Vol. 2 No. 3 (2023): Lombok Medical Journal Volume 2 Nomor 3
Publisher : Faculty of Medicine, Universitas Mataram

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.29303/lmj.v2i2.2851

Abstract

Abstract: Dengue is one of the most common mosquito-borne diseases in tropical and subtropical climates. So far there are no effective antivirals available for the treatment of DENV infection, which in this case requires alternative treatments that can be a cure as well as prevention for dengue fever. Alternative treatment that can be used is by using plants, one of which is guava. In guava leaves, there are various compounds that are efficacious as anti-dengue fever, namely flavonoid compounds such as quercetin and tannins which are believed to inhibit the growth of dengue viruses. The purpose of writing this manuscript is to discuss the potential of quercetin compounds in guava leaves in the management of dengue fever. Keywords: Dengue hemorrhagic fever, alternative medicine, antiviral, guava leaf, quercetin, ethnomedicine