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All Journal Communication in Biomathematical Sciences Sriwijaya Journal of Surgery
Afifurrahman
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Medicine & Pharmacology Social Sciences

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The Interplay of Common Noise and Finite Pulses on Biological Neurons Afifurrahman; Mohd Hafiz Mohd; Farah Aini Abdullah
Communication in Biomathematical Sciences Vol. 6 No. 2 (2023)
Publisher : The Indonesian Bio-Mathematical Society

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.5614/cbms.2023.6.2.5

Abstract

The response of neurons is highly sensitive to the stimulus. The stimulus can be associated with a direct injection in vitro experimentation (e.g., time dependent and independent inputs); or post-synaptic potentials resulting from the interaction of many neurons. A typical incoming stimulus resembles a noise which in principle can be described as a random variable. In computational neuroscience, the noise has been extensively studied for different setups. In this study, we investigate the effect of noisy inputs in a minimal network of two identical leaky integrate-and-fire (LIF) neurons interacting with finite pulses. In particular, we consider a Gaussian white noise as a standard function for stochastic modelling of neurons, while taking into account the pulse width as an elementary component for the signal transmission. By exploring the role of noise and finite pulses, the two neurons show a synchronous spiking behaviour characterized by fluctuations in the interspike intervals. Above some critical values the synchronous regime collapses onto asynchronous dynamics. The abrupt change in such dynamics is accompanied by a hysteresis, i.e., the coexistence of synchronous and asynchronous firing behaviour.
Efficacy of Randu Honey Supplementation on Callus Formation in Closed Fractures of the Tibia in Wistar Rats Afifurrahman; Wiria Aryanta; Mgs Irsan Saleh
Sriwijaya Journal of Surgery Vol. 7 No. 2 (2024): Sriwijaya Journal of Surgery
Publisher : Surgery Department, Faculty of Medicine Universitas Sriwijaya

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.37275/sjs.v7i2.101

Abstract

Introduction: Tibial fracture is one of the most common injuries. Randu honey has the potential to speed up fracture healing. This study aims to determine the efficacy of randu honey supplementation on callus formation in closed fractures of the tibia in Wistar rats. Methods: This research uses a true experimental design with post test only control group design. A total of 36 Wistar rats were divided into two groups, namely the control group and the treatment group which were given 200g/BW(gram)/day of randu honey. Fractures were made on the rat tibia and callus diameter was measured at 3 weeks after treatment. Results: The callus diameter in the treatment group was significantly larger than the control group (p<0.05) in radiological and macroscopic measurements. Conclusion: Supplementation with randu honey is effective in the formation of callus in closed fractures of the tibia in Wistar rats.
Co-Authors Farah Aini Abdullah Mgs Irsan Saleh Mohd Hafiz Mohd Wiria Aryanta