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All Journal Jurnal Respirasi (JR) Jurnal Klinik dan Riset Kesehatan Journal of General Procedural Dermatology and Venereology Indonesia
Dani, Adinda Amalia
Unknown Affiliation
Biochemistry, Genetics & Molecular Biology Health Professions Medicine & Pharmacology Nursing Public Health

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Aspergilosis Kutis Primer dengan Gambaran Klinis Menyerupai Tuberkulosis Verukosa Kutis Dani, Adinda Amalia; Widasmara, Dhelya
Jurnal Klinik dan Riset Kesehatan Vol 2 No 1 (2022): Edisi Oktober
Publisher : RSUD Dr. Saiful Anwar Province of East Java

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.11594/jk-risk.02.1.8

Abstract

Pendahuluan: Aspergilosis kutis primer (AKP) adalah infeksi jamur invasif pada kulit yang jarang terjadi namun dapat mengancam jiwa. Penyakit ini disebabkan oleh Aspergillus spp dan termasuk ke dalam mikosis profunda (subkutan). Laporan kasus: Seorang laki-laki berusia 63 tahun datang dengan keluhan luka pada kulit di kaki kanan sejak 5 tahun yang gatal, nyeri dan bernanah. Pemeriksaan dermatologis menunjukkan papul dan plak eritematosa multipel, permukaan verukosa sebagian tertutup krusta kuning kecoklatan, xerosis dan beberapa ulkus dengan pus. Diagnosis banding yang diajukan adalah Tuberkulosis verukosa kutis, Kromoblastomikosis dan Misetoma. Hasil kultur jaringan menunjukkan Aspergillus niger. Hasil biopsi menunjang diagnosis mikosis profunda. Pasien kemudian didiagnosis sebagai Aspergilosis kutis primer, diberikan terapi dosis denyut Itrakonazol dan mengalami perbaikan klinis dalam 2 minggu. Kesimpulan: Gambaran klinis atipikal pada pasien ini memberikan tantangan diagnostik bagi dermatologis. Pentingnya penegakan diagnosis pada pasien dengan mikosis profunda adalah untuk mengidentifikasi penyebab, menentukan tatalaksana tepat dan mencegah komplikasi.
Aspergilosis Kutis Primer dengan Gambaran Klinis Menyerupai Tuberkulosis Verukosa Kutis Dani, Adinda Amalia; Widasmara, Dhelya
Jurnal Klinik dan Riset Kesehatan Vol 2 No 1 (2022): Edisi Oktober
Publisher : RSUD Dr. Saiful Anwar Province of East Java

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.11594/jk-risk.02.1.8

Abstract

Background: Primary cutaneous aspergillosis (PCA) is a rare invasive fungal infection of the skin that can be life-threatening. This disease is caused by Aspergillus spp and belongs to the deep mycosis (subcutaneous) group. Case report: A 63-year-old man came with complaint of wound that feels itchy, painful and exudative on right lower leg since 5 years ago. Dermatological examination showed multiple erythematous papules and plaques with verrucous surface partially covered in brownish yellow crust accompanied by xerosis and some ulcers with pus. The proposed differential diagnoses are Tuberculosis verrucosa cutis, Chromoblastomycosis and Mycetoma. The result of tissue culture showed Aspergillus niger. Biopsy result supports the diagnose of deep mycosis. The patient then diagnosed as primary cutaneous aspergillosis, treated with pulse dose Itraconazole and improved clinically within 2 weeks. Conclusion: Atypical manifestation in this patient gives diagnostic challenge for dermatologist. The importance of establishing diagnosis in patient with deep mycoses are to identify the cause, determine the appropriate treatment and prevent cimplication.
Serial Excision of a Nevus Sebaceous of Jadassohn on the Scalp Sugiatno, Belladikna Brillianty; Widiatmoko, Arif; Dani, Adinda Amalia; Retnani, Diah Prabawati
Journal of General - Procedural Dermatology & Venereology Indonesia Vol. 9, No. 1
Publisher : UI Scholars Hub

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Abstract

Background: Nevus sebaceous of Jadassohn (NSJ) is a non-hereditary hamartoma of the skin’s adnexal structures. The incidence of NSJ in newborns is estimated at 0.1-0.3% with no gender or ethnic propensity. Surgical excision is a common treatment for NSJ, although there is no definite consensus on the timing or recommendations for the removal. This article aims to present the advantages of serial excision therapy in a case of NSJ. Case Illustration: A 14-year-old male presented with a complaint of a bump on the scalp since birth, which had progressively enlarged during puberty. Dermatological examination revealed a well-demarcated, yellow-orange verrucous plaque with irregular borders measuring 3x3.5 cm. The diagnosis was confirmed through dermoscopy and histopathology. The patient underwent a three-stage serial excision at 3-4-week intervals. Discussion: The excision technique for NSJ excision was selected based on the location and size of the lesion. Serial excision is a widely used and straightforward method. This method was chosen due to the lesion’s large area. However, NSJ excision on the scalp presents its own challenges due to limited soft tissue flexibility, hair-bearing skin, and a convex surface, which may affect reconstruction outcomes. Conclusion: The three-stage serial excision resulted in complete removal of the NSJ, minimal scarring without significant alopecia, and no recurrence during the 6-month follow-up.
Persistent Pneumothorax in Neurofibromatosis Type-1 Simamora, Hustorio Aliongko; Djajalaksana, Susanthy; Chozin, Iin Noor; Erawati, Dini Rachma; Yudhanto, Hendy Setyo; Damanik, Gracelia Ruth Elisabeth; Dani, Adinda Amalia; Listyoko, Aditya Sri
Jurnal Respirasi Vol. 12 No. 1 (2026): January 2026
Publisher : Faculty of Medicine Universitas Airlangga

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.20473/jr.v12-I.1.2026.64-70

Abstract

Introduction: Neurofibromatosis type 1 (NF-1) is a rare autosomal dominant disorder. While typically recognized by its cutaneous features, pulmonary involvement, including apical cysts and basal interstitial fibrosis consistent with interstitial lung disease (ILD), can occur in up to 20% of patients. These manifestations create a predisposition to complications such as spontaneous pneumothorax. While this is relatively uncommon, occurring in approximately 1.5% of patients with NF-1, it represents a serious and potentially life-threatening complication when it does occur. Case: A 52-year-old male with a 20-pack-year smoking history and active pulmonary tuberculosis (TB) presented with acute chest pain and dyspnea. Dermatological examination and skin biopsy confirmed the diagnosis of NF-1. A high-resolution computed tomography (HRCT) scan of the chest revealed multiple subpleural pulmonary cysts consistent with NF-1-related ILD, alongside findings suggestive of active TB. The patient was diagnosed with a secondary spontaneous pneumothorax (SSP), which proved to be persistent despite initial chest tube drainage, ultimately requiring surgical intervention. Conclusion: This case highlights that NF-1 is a significant underlying risk factor for persistent pneumothorax, particularly when co-existing with other conditions like active TB and a history of smoking. The chronic inflammation and parenchymal destruction associated with these comorbidities can exacerbate the inherent structural lung abnormalities in NF-1, leading to complex, difficult-to-manage clinical scenarios. Early recognition of pulmonary manifestations in patients with NF-1 is crucial for anticipating and managing severe complications.
Co-Authors Chozin, Iin Noor Damanik, Gracelia Ruth Elisabeth Dhelya Widasmara Djajalaksana, Susanthy Erawati, Dini Rachma Listyoko, Aditya Sri Retnani, Diah Prabawati Simamora, Hustorio Aliongko Sugiatno, Belladikna Brillianty Widiatmoko, Arif Yudhanto, Hendy Setyo