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All Journal Jurnal Respirologi Indonesia JURNAL ILMIAH SIMANTEK Patria : Jurnal Pengabdian Kepada Masyarakat Ibnu Sina: Jurnal Kedokteran dan Kesehatan - Fakultas Kedokteran Universitas Islam Sumatera Utara
SAPUTRA, LILI ANANTA
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Religion Agriculture, Biological Sciences & Forestry Humanities Computer Science & IT Decision Sciences, Operations Research & Management Economics, Econometrics & Finance Education Environmental Science Health Professions Languange, Linguistic, Communication & Media Law, Crime, Criminology & Criminal Justice Mathematics Medicine & Pharmacology Nursing Public Health Social Sciences Other

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FOLLICULAR CHOLECYSTITIS : A CASE REPORT OF UNCOMMON MORPHOLOGICAL SPECTRUM OF GALLBLADDER LESIONS SAPUTRA, LILI ANANTA
JURNAL ILMIAH SIMANTEK Vol 8 No 1 (2024): JURNAL ILMIAH SIMANTEK
Publisher : LP2MTBM MAKARIOZ

Show Abstract | Download Original | Original Source | Check in Google Scholar

Abstract

Background: A very uncommon subtype of chronic cholecystitis is follicular cholecystitis (FC). Hyperplastic lymphoid follicles and noticeable germinal centers are its defining features. About 2% of standard cholecystectomies involve it. A very uncommon form of chronic cholecystitis is follicular cholecystitis. At least three lymphoid follicles per cent of the gall bladder tissue and an inflammatory infiltrate that is almost entirely made up of dispersed, well-formed lymphoid follicles define it. To prevent misinterpretation of lymphoma, the pathologist needs to be knowledgeable with this condition. Objective: To educate pathologists about this entity, this case is being presented. Case description: We describe a case of FC in a 42-year-old woman in this article. Her abdominal pain was clinically determined to be calculus cholecystitis, and laparoscopic cholecystectomy was used to treat it. It was grossly observed that the gall bladder wall had thickened. A histopathological study showed that the gall bladder wall was heavily infiltrated with lymphocytes, which produced lymphoid follicles with distinct germinal centers. We therefore determined that FC was the cause. This growth should not be confused with lymphoma. A thorough histological analysis is diagnostic, and immunohistochemistry may be used in some cases. Conclusion: This case was used to highlight the rarity of follicular cholecystitis. It is a benign and extremely uncommon entity that frequently looks like lymphoma. FC does not seem to be associated with autoimmunity, lymphoma, or obstructive pathologies.
Edukasi Bahaya Merokok dan Kanker Payudara serta Lokakarya Berhenti Merokok dan SADARI di SMA Immanuel Kalasan Yogyakarta Saputra, Lili Ananta; Widowati, Galuh; Jayadi, Tejo; Haryaningtyas, Estherina Fajar; Jawa, Tresia
Patria : Jurnal Pengabdian Kepada Masyarakat SPECIAL ISSUE - SENDIMAS IX
Publisher : Universitas Katolik Soegijapranata

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.24167/patria.v1i1.12727

Abstract

Kanker menjadi penyebab kematian kedua terbanyak di dunia. Provinsi Daerah Istimewa Yogyakarta (DIY) berada pada peringkat pertama prevalensi kanker terbanyak. Edukasi mengenai kanker diharapkan dapat membantu meningkatkan kesadaran masyarakat untuk menjauhi faktor risiko kanker dan melakukan deteksi dini sehingga angka kejadian kanker dapat berkurang.  Departemen Patologi Anatomik Fakultas Kedokteran Universitas Kristen Duta Wacana (PA FK UKDW) mengadakan program pengabdian masyarakat berupa edukasi dengan topik bahaya merokok dan kanker payudara, dilanjutkan dengan lokakarya berhenti merokok dan pemeriksaan payudara sendiri (SADARI) di SMA Immanuel Kalasan, Yogyakarta. Target peserta yang hadir adalah seluruh guru dan siswa sebanyak 46 orang. Metode yang digunakan dalam kegiatan ini adalah ceramah interaktif. Materi edukasi yang disampaikan adalah mengenai definisi, gejala, pencegahan, dan deteksi dini kanker payudara serta bahaya merokok. Lokakarya dibagi menjadi 2 kelompok. Peserta laki-laki mengikuti lokakarya berupa diskusi dan komitmen untuk berhenti merokok. Peserta perempuan mengikuti lokakarya SADARI, dibagi menjadi kelompok kecil dan masing-masing memeragakan Teknik SADARI. Peserta antusias mengikuti kegiatan ini dengan mengajukan pertanyaan dan berpartisipasi aktif dalam lokakarya. Diharapkan dengan adanya kegiatan ini, pengetahuan mengenai kanker pada usia sekolah semakin meningkat dan juga meningkatkan kesadaran untuk SADARI dan berhenti merokok. Program edukasi kesehatan dan lokakarya ini diharapkan dapat terus berlanjut dengan target sasaran yang lebih luas.
PENDEKATAN DIAGNOSIS LESI KISTIK REGIO COLLI: DIAGNOSTIC APPROACH OF CYSTIC NECK LESION Wijayanti, Arini Rizky; Setiyandari, Bernadeta Hernik; Saputra, Lili Ananta
Ibnu Sina: Jurnal Kedokteran dan Kesehatan - Fakultas Kedokteran Universitas Islam Sumatera Utara Vol. 25 No. 1 (2026): Januari 2026
Publisher : Faculty of Medicine Universitas Islam Sumatera Utara

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.30743/ibnusina.v25i1.1036

Abstract

Lesi kistik di regio colli merupakan temuan klinis yang sering dijumpai dan memiliki variasi etiologi yang luas, mulai dari kelainan bawaan, infeksi dan neoplasma. Penegakan diagnosis yang tepat sangat penting untuk menentukan terapi yang sesuai dan mencegah komplikasi. Tinjauan pustaka naratif ini dilakukan melalui pencarian literatur pada Google Scholar antara tahun 2015–2025 dengan kata kunci: “cystic neck lesion”, “neck cyst”, “diagnostic approach”, “ultrasound”, “CT”, “MRI”, dan “fine needle aspiration”. Kriteria inklusi meliputi artikel yang membahas aspek diagnostik lesi kistik leher pada manusia, berbahasa inggris atau indonesia, dan diterbitkan tahun 2015–2025. Artikel yang tidak relevan, duplikasi, atau tanpa akses teks penuh dikeluarkan. Dari 17.100 artikel, 29 artikel memenuhi kriteria dan dianalisis secara kualitatif. Pemeriksaan klinis dengan pendekatan lokasi, pencitraan (ultrasonografi/ USG, CT scan, MRI) dan sitopatologi (fine needle aspiration biopsy/ FNAB) memiliki peran komplementer dalam diagnosis lesi kistik di regio colli. Pemeriksaan USG merupakan modalitas pemeriksaan penunjang awal paling efektif, sementara CT scan/MRI memberikan karakterisasi lebih mendalam dan menilai keterlibatan jaringan sekitar. Pemeriksaan FNAB membantu membedakan proses infeksi dan neoplasma, meskipun sensitivitasnya menurun pada lesi yang bersifat kistik. Kombinasi multimodal meningkatkan akurasi diagnostik. Kesimpulan: Pendekatan multidisiplin yang mengintegrasikan data klinis, radiologis, dan sitopatologis disarankan untuk diagnosis komprehensif lesi kistik ldi regio colli.
The Relationship between Smoking History with ECOG Score, EGFR Mutation Status, and Clinicopathology Data of NSCLC Patients: Preliminary Study Jayadi, Tejo; Amarantini, Charis; Saputra, Lili Ananta; Pratiwi, Johana Puspasari Dwi; Widowati, Fransiska Galuh
Jurnal Respirologi Indonesia Vol 46 No 1 (2026)
Publisher : Perhimpunan Dokter Paru Indonesia (PDPI)/The Indonesian Society of Respirology (ISR)

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.36497/jri.v46i1.1044

Abstract

Background: Patients with non-small cell lung cancer (NSCLC) have a poor outcome. Mutations in the EGFR gene play a crucial role in determining treatment options and prognosis. Smoking history, clinicopathological features, including patient performance, and EGFR gene mutation have served as clinical guidelines for monitoring. This study aims to examine the association between smoking history and ECOG score, EGFR mutation status, and clinicopathological characteristics of patients with NSCLC in Yogyakarta. Methods: An observational and analytic study, with a retrospective cohort design from 32 patients diagnosed with NSCLC. Data on smoking history, clinicopathological characteristics, ECOG performance scores, and EGFR mutation types (Exon 19 deletion and Exon 21 L858R) were extracted and concluded from medical records. The relationship between these variables was analysed using the Chi-square test. Results: The analysis began by exploring the relationship between smoking history and initial ECOG performance scores. It was discovered that non-smokers exhibited poorer initial ECOG scores (P=0.025). Smoking history was significantly associated with specific EGFR mutation types (P=0.009), but not with overall EGFR mutation status. The analysis revealed that deletions on Exon 19 were mainly found in patients who smoked, whereas mutations in Exon 21 were uniquely present in non-smokers. Clinical follow-up also shows an association (P=0.002). This finding suggests that smoking behaviour interferes with the carcinogenesis of NSCLC. Conclusion: The relationship between smoking history, performance status, exon-specific EGFR mutations, and clinical follow-up suggests differences in the carcinogenic mechanisms of NSCLC exon-specific mutations, highlighting biological diversity and emphasizing the need for detailed molecular studies to improve prognostic accuracy.
Co-Authors CHARIS AMARANTINI Haryaningtyas, Estherina Fajar Jawa, Tresia Pratiwi, Johana Puspasari Dwi Setiyandari, Bernadeta Hernik Tejo Jayadi, Tejo Widowati, Fransiska Galuh Widowati, Galuh WIJAYANTI, ARINI RIZKY