Article Per Year (5 Year)
p-Index From 2021 - 2026
0.817
P-Index
This Author published in this journals
All Journal Jurnal Pengabdian Ilmu Kesehatan Jurnal Analis Kesehatan Kendari
Yanti Sunaidi
Unknown Affiliation
Biochemistry, Genetics & Molecular Biology Chemistry Health Professions Immunology & microbiology Public Health

Published : 3 Documents Claim Missing Document
Claim Missing Document
Check
Articles

Found 3 Documents
Search

 1 
Skrining Kesehatan Melalui Pemeriksaan Asam Urat di Kompleks Aditarina Kota Makassar Mutmainnah Abbas; Rosdiana Mus; Thaslifa Thaslifa; Yanti Sunaidi; Fitriana Fitriana
Jurnal Pengabdian Ilmu Kesehatan Vol. 3 No. 1 (2023): Maret : Jurnal Pengabdian Ilmu Kesehatan
Publisher : Pusat Riset dan Inovasi Nasional

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.55606/jpikes.v3i1.1670

Abstract

Degenerative disease is one of the classes of diseases whose incidence is related to the degeneration process in old age whose development is directly related to time and age. This usually affects the joints, namely gout. Uric acid is the final metabolic product of purine, which is a component of nucleic acid found in the nucleus of body cells. Increased uric acid levels in the blood are not only caused by food consumed but there are several other factors, namely age, gender, body mass index, and genetics. In addition, in the elderly there is a decrease in the function of vital organs such as the liver and kidneys which can cause an increase in uric acid levels in the blood. The purpose of this study is health screening through uric acid examination. The method used was descriptive by involving 27 respondents who were willing to become subjects. The results showed that there were 10 respondents with increased uric acid examination results while 17 subjects showed normal uric acid examination results.
Perbedaan Kadar Tumor Necrosis Factor Alpha pada Pekerja Finishing Gitar Berdasarkan Penggunaan Alat Pelindung Diri Dan Lama Bekerja Antoni Aldo Danendra Sawal; Eleventi Oktariani Putri; Muhammad Ihza Lisan Shidqi; Yanti Sunaidi
Jurnal Analis Kesehatan Kendari Vol. 8 No. 1 (2025): Jurnal Analis Kesehatan Kendari (JAKK) : Vol. 8 (1) Desember 2025)
Publisher : Program Study of Medical Laboratory Technology , Politeknik Bina Husada Kendari

Show Abstract | Download Original | Original Source | Check in Google Scholar

Abstract

Debu kayu dan zat kimia dari pengecatan gitar selama proses finishing yang masuk ke saluran pernapasan dapat mengaktifkan sistem imun seluler dan saat terjadinya inflamasi menyebabkan pelepasan sitokin pro-inflamasi yaitu Tumor Necrosis Factor Alpha (TNF-α). TNF-α merupakan sitokin pro-inflamasi yang memiliki efek agregasi dan stimulasi neutrofil. TNF-α disekresikan oleh makrofag, yang berperan dalam metabolisme, termasuk diferensiasi, apoptosis, proliferasi sel, koagulasi, dan metabolisme lipid. Penelitian ini merupakan penelitian observasional, dengan rancangan penelitian potong lintang di desa gitar Sukoharjo. Sampel penelitian sebanyak 30 subjek, diambil menggunakan teknik non-probability sampling dengan metode purposive sampling. Pemeriksaan TNF-α dilakukan dengan metode Enzyme-Linked Immunosorbent Assay (ELISA). Hasil penelitian menunjukkan bahwa nilai rata-rata TNF-α pada pekerja finishing gitar yang memakai APD dengan masa kerja 1-3 tahun adalah 66,66 pg/ml, sedangkan pada pekerja yang memakai APD dengan masa kerja >3 tahun adalah 70,71 pg/ml. Nilai rata-rata pada pekerja yang tidak memakai APD dengan masa kerja 1-3 tahun adalah 71,64 pg/ml, sedangkan pada pekerja yang tidak memakai APD selama >3 tahun adalah 86,10 pg/ml. Kesimpulan dari penelitian ini adalah terdapat perbedaan kadar TNF-α berdasarkan penggunaan APD yang bekerja selama 1-3 tahun maupun >3 tahun.
Analisis Retrospektif Hasil Pemeriksaan Tiroid (TSH dan FT4) dengan Metode ELFA di RSUD Dr. Doris Sylvanus Palangka Raya Eleventi Oktarina Putri; Antoni Aldo Danendra Sawal; Muhammad Ihza Lisan Shidqi; Yanti Sunaidi
Jurnal Analis Kesehatan Kendari Vol. 8 No. 1 (2025): Jurnal Analis Kesehatan Kendari (JAKK) : Vol. 8 (1) Desember 2025)
Publisher : Program Study of Medical Laboratory Technology , Politeknik Bina Husada Kendari

Show Abstract | Download Original | Original Source | Check in Google Scholar

Abstract

Thyroid disorders are among the most prevalent endocrine conditions globally, demanding precise diagnostic methodologies for effective management. Epidemiological data on thyroid disorders in Kalimantan is still limited. This study aims to re-analyze retrospective data on .thyroid stimulating hormone (TSH) and free thyroxine (FT4) levels measured using the Enzyme Linked Fluorescent Assay (ELFA) method in 2017 at RSUD Dr. Doris Sylvanus Palangka Raya, evaluate them with the latest guidelines, and validate the ELFA method. Data from 87 patients with suspected thyroid dysfunction were subjected to descriptive statistics, Chi-square tests, Spearman's correlation, and Receiver Operating Characteristic (ROC) curve analysis. Patients were predominantly female (n=67, 77%). Hormone distribution showed a tendency towards hyperthyroidism, with 48.3% (n=42) of patients having low TSH and 27.6% (n=24) having high FT4. Statistical analysis showed no significant association between gender and TSH (χ² = 1.277, df = 2, p = 0.528) or FT4 (χ² = 3.240, df = 2, p = 0.198) levels. However, a very strong and significant physiological relationship was found between TSH and FT4 levels, both categorically (χ² = 24.576, df = 4, p < 0.001) and correlationally (r = -0.503, p < 0.001). ROC analysis proved that the ELFA method has very good diagnostic accuracy with an Area Under Curve (AUC) of 0.915 (95% CI: 0.835–0.995, p < 0.001). The profile of thyroid disorders in this region is dominated by a hyperthyroidism pattern, and historical data from the ELFA method has been proven to remain valid and clinically relevant for epidemiological studies. These findings affirm that data generated by ELFA technology in 2017 remains robust and clinically valid when interpreted through the lens of modern guidelines. The study underscores the value of simultaneous TSH-FT4 testing and supports the sustained utility of older, yet reliable, immunoassay technologies, particularly in resource-limited settings, contributing to longitudinal epidemiological understanding of thyroid disorders in the region.
Co-Authors Antoni Aldo Danendra Sawal Eleventi Oktariani Putri Eleventi Oktarina Putri Fitriana Fitriana Imelda pongsimpin Muhammad Ihza Lisan Shidqi Mus, Rosdiana Mutmainnah Abbas Taufiq, Nuramaniyah Thaslifa Thaslifa