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All Journal Journal of Islamic Pharmacy Jurnal Epidemiologi Kesehatan Komunitas
Norachuriya, Zedny
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Biochemistry, Genetics & Molecular Biology Chemistry Health Professions Immunology & microbiology Medicine & Pharmacology Public Health

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Kajian Perilaku Kepatuhan Medikasi Pasien Tuberculosis Paru di Kabupaten Ngawi: Sebuah Model Matematis Kartini, Puri Ratna; Norachuriya, Zedny; Novitasari, Karisma Surya; Shintawati, Shefina; Wisnubroto, Agung Praboow
Jurnal Epidemiologi Kesehatan Komunitas Vol 9, No 2 : Agustus 2024
Publisher : Master of Epidemiology, Faculty of Public Health, Diponegoro University, Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.14710/jekk.v9i2.20982

Abstract

Background: Tuberculosis (TB)  is currently still a health issue in Indonesia. Indonesia is the country that contributes the second largest number of tuberculosis cases after India. Ngawi is one of the cities in East Java Province with a large number of tuberculosis cases. In 2022, tuberculosis cases in Ngawi Regency will double from the previous year with the death rate also increasing from the previous year. This shows that tuberculosis control in Ngawi Regency has not been effective. Efforts are needed to increase medication compliance in tuberculosis sufferers so that therapeutic success can be achieved so that the death rate and tuberculosis transmission rate can be reduced.Methods: This research is an analytical observational study with a cross sectional research design which aims to create a mathematical model of medication adherence in pulmonary TB sufferers in Ngawi Regency. This research involved 102 pulmonary TB sufferers at Dr. Soeroto Hospital, Widodo Hospital and Ngawi Regency Health Center. Pulmonary TB sufferers were selected using a purposive sampling technique. Data were analyzed using multiple logistic regression tests.Result: Based on interviews conducted with 102 respondents, the results obtained were that the variables age, length of treatment, motivation to recover, self-perception, knowledge, access to health facilities, medication assistance, family support, drug side effects and health facility administration were candidates for bivariate testing.Conclusion : The variables of self-perception, knowledge, family support and health facility administration are the dominant factors influencing medication compliance in pulmonary TB sufferers in Ngawi Regency in 2023.
Pengaruh Kombinasi Kitosan dan Karbopol 940 Terhadap Karakteristik Fisik dan Stabilitas Sediaan Gel Ekstrak Daun Kelor (Moringa oleifera L) Zatalini, Dioni Fadia; Bhagawan, Weka Sidha; Norachuriya, Zedny
Journal of Islamic Pharmacy Vol 10, No 1 (2025): J. Islamic Pharm.
Publisher : Universitas Islam Negeri Maulana Malik Ibrahim Malang

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.18860/jip.v10i1.32255

Abstract

Gel merupakan salah satu sediaan topikal yang memiliki keuntungan seperti bewarna jernih, memberikan sensasi dingin, tidak berminyak, mudah menyebar di kulit sehingga dapat maksimal memberikan efek teraupetik. Gelling agent merupakan komponen penting dalam pembentukan gel. Kitosan merupakan polimer alam yang dapat membentuk gel pada larutan asam. Sedangkan karbopol 940 dapat menghasilkan gel bewarna jernih dan stabilitasnya baik selama penyimpanan. Tujuan dari penelitian ini adalah untuk mengetahui pengaruh kombinasi karbopol 940 dan kitosan pada sediaan gel ekstrak daun kelor terhadap karakteristik fisik dan uji stabilitas selama 4 minggu. Pembuatan gel ekstrak daun kelor menggunakan ekstrak etanol daun kelor sebesar 5%. Kombinasi gelling agent yaitu karbopol 940 1% dan kitosan 0,5%, 1%, 1,5%. Uji karakteritik dan stabilitas meliputi organoleptis, homogenitas, pH, viskositas, daya sebar dan stabilitas selama 4 minggu. Hasil menunjukkan gel ekstrak daun kelor bewarna coklat tua, kental, bau khas daun kelor serta homogen dan tidak mengalami perubahan signifikan selama disimpan 28 hari. Nilai Uji pH sediaan gel ekstrak daun kelor tidak mengalami perubahan setelah disimpan selama 4 minggu (4,94-5,20) menjadi 5,09-5,65). Stabilitas viskositas sediaan gel ekstrak daun kelor mengalami penurunan dari minggu ke-1 2,964 cps-4420 cps menjadi 2,438 cps-3556 cps setelah minggu. Pada uji daya sebar terjadi peningkatan setelah disimpan selama 4 minggu (4,2 cm- 5,9 cm menjadi (5,1 cm – 6,9 cm). Berdasarkan hasil tersebut semua formula gel kitosan-karbopol 940-ekstrak daun kelor telah memenuhi persyaratan.
Co-Authors Kartini, Puri Ratna Novitasari, Karisma Surya Shintawati, Shefina Weka Sidha Bhagawan Wisnubroto, Agung Praboow Zatalini, Dioni Fadia